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COPD
Munzenberger
11
Pharmacology
Pre-School
01/08/2010

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Cards

Term
Initial COPD presentation
Definition
chronic sputum producing cough; dyspnea; FEV1:FVC < 70; bronchodilator response to <80; <12% increase in FEV1 w/bronchodilator
Term
severe presentation of COPD
Definition
cyanosis; barrel chest; + resp rate; pursed lips at respiration; retractions; peripheral edema
Term
Ipratropium
Definition
onset 15-20 mins (slower than albuterol); used for rescue but not best; d 4-6h
Term
tiotropium
Definition
onset 30 mins; no tolerance; d 24h w peak @ 6h
Term
formoterol
Definition
5 min onset; d 4-6h
Term
salmeterol
Definition
onset 15-20 min; d 4-6h
Term
theophylline
Definition
used in pt unable to use inhalers; reduce dyspnea; improves exercise capacity; therapeutic range 8-15 mcg/ml severe side effects above that
Term
Mild COPD tx
Definition
FEV1/FVC <70, FEV1 >80. Albuterol prn
Term
Moderate COPD presentation, tx
Definition
Fev/FVC <70; 50
Term
Stage III COPD presentation, tx
Definition
30
Term
Stage IV COPD presentation
Definition
FEV/FVC<70; FEV<30 or FEV<50 w/resp failure; add oxygen, consider surgical options
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