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Cytogenetic Abnormalities in Hematologic Malignancies
Cytogenetic Abnormalities in Hematologic Malignancies
7
Medical
Professional
11/30/2012
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Term
t(9;22)
 Definition
BCR-ABL aka Philadelphia Chromosome. Seen in CML, ALL, and, less frequently, AML.
Term
BCR-ABL, p210 isoform
 Definition
Associated with CML
Term
BCR-ABL, p190 isoform
 Definition
Associated with ALL
Term
t(8;21)
 Definition
AML-ETO1. Seen in AML.
Term
t(15;17)
 Definition
PML-RARA. Seen in APML.
Term
CBFβ-MYH11
 Definition
inv(16) or t(16;16). Seen in AML.
Term
t(8;9)
 Definition
JAK2. Seen in MDS/MPS, atypical CML, CMML, AML (M7), JMML.
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