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derm - carcinomas
PA CLin Med
60
Health Care
Graduate
12/09/2009

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Cards

Term
most common cutaneous malignancy:
Definition
basal cell carcinoma
Term
does BCC usually metastisize?
Definition
nope
Term
5 variants of BCC:
Definition
1. nodular
2. pigmented
3. superficial
4. micronodular
5. morpheaform
Term
most common form of BCC:
Definition
nodular
Term
BCC: pearly pink, telangiectasia, frequently ulcerate, bleed & become crusted in the center
Definition
Nodular BCC
Term
BCC: may resemble a malignant melanoma
Definition
pigmented BCC
Term
BCC: least agressive, more common on trunk and extremities, flat lesion that spreads peripherally:
Definition
superficial BCC
Term
BCC: recurs more frequently after tx due to extends beyond clinical borders
Definition
micronodular
Term
which of the variants of BCC is hardest to tx:
Definition
morpheaform and sclerosing BCC
Term
BCC: most subtle & least common
Definition
morpheaform & sclerosing BCC
Term
morpheaform & sclerosing BCC resemble:
Definition
scar tissue
Term
BCC tx:
Definition
1. ED & C
2. excision (ck surgical margins)
3. Mohs micrographic surgery
4. Radiation
Term
ED & C is not good for which BCC?
Definition
recurrent; 60% cure rate
Term
best tx option for recurrent BCC:
Definition
Mohs micrographic surgery
Term
tx of choice for morpheaform BCC:
Definition
Mohs micrographic surgery
Term
what is the cure rate for mohs surgery & primary tumors? recurrent tumors?
Definition
primary tumors: 99%
recurrent tumors: 96%
Term
indications for radiation tx of BCC
Definition
1. tumors difficult to tx surgically
2. pt unwilling/unable to undergo sgy
3. don't use in children due to exposure concerns
Term
most common on sun exposed areas, keratotic lesions with malignant porential:
Definition
Actinic Keratosis
Term
actinic keratosis can (and will in 10-20%) progress to:
Definition
SCC
Term
actinic keratosis lesion:
Definition
poorly defined area of redness with thin scale, over time scale thickens and becomes yellowish
Term
how is actinic keratosis from SCC?
Definition
bx is needed
Term
actinic keratosis tx:
Definition
1. Avoid sun
2. cryotherapy
3. topical 5-FU
Term
2nd most common skin cancer:
Definition
SCC
Term
does SCC metastisize?
Definition
may have local or distant metastasis
Term
common places for SCC:
Definition
1. head
2. neck
3. hands
Term
6 risk factors for SCC:
Definition
1. fait complexion
2. UV light exposure
3. radiation
4. chemicals
5. HPV
6. immunosupression
Term
red lesions with poorly defined base and yellow white scale:
Definition
SCC or AK, bx to determine
Term
Bowens SCC:
Definition
SCC in situ
Term
intraepidermal SCC
Definition
SCC in situ
Term
SCC in situ: metastisize?
Definition
nope, but may become invasive
Term
SCC tx:
Definition
1. wide local excision
2. Mohs
3. check assoc lymph nodes for mets
Term
rapidly growing crateriform nodule, considered low grade SCC:
Definition
Keratocanthoma
Term
describe keratocanthoma lesion:
Definition
solitary volcano shaped, tender lesion with keratotic plug
Term
prognosis for keratocanthoma:
Definition
may resolve spontaneously or progress into invasive SCC
Term
"Mole Cancer"
Definition
Melanoma
Term
5 risk factors for melanoma:
Definition
1. fair skin/light colored hair/eyes
2. Hx of blistering sunburn
3. Hx of abn nevi
4. FHx or personal Hx of melanoma
5. congenital nevi (born w mole)
Term
most common early sx of melanoma:
Definition
itching but most are asx
Term
later sx of melanoma include:
Definition
tenderness, ulceration, bleeding
Term
where does melanoma come up?
Definition
can come up anywhere even areas protected from the sun
Term
which color is indicative of melanoma?
Definition
gray black blue pinkn red white are all possible indicators
Term
ABCDE of melanoma
Definition
A - asymmetry
B - borders (irregular)
C - color (variable not consistant)
D - Diameter (large)
E - Evolution (changes)
Term
Lentigo Maligna: AKA
Definition
In situ melanoma
Term
describe lentigo maligna:
Definition
slowly progressing melanoma, may start as age spot, flat irregular outline, variation in color density
Term
Melanoma Tx:
Definition
1. check assoc lymphs for mets & bx if indicated
2. excise for bx & may b curative
Term
what is indicative of better prognosis of melanoma?
Definition
thinner breslow depth
Term
malignancy of lymphatic endothelial cells, assoc w gamma herpes virus (HSV8)
Definition
Kaposi's sarcoma
Term
clasic kaposi's presentation:
Definition
purple patches on distal lower legs that progress proximally
Term
Kaposi's sarcoma tx:
Definition
1. single lesion - excision
2. multiple lesions - XRT
Term
freckles: AKA
Definition
lentigo or lentigines
Term
Nevi: flat or slightly raised, skin markings preserved on surface, common in children:
Definition
Junctional nevi
Term
common locations for junctional nevi:
Definition
1. palms
2. soles
3. genitalia
4. mucosa
Term
Nevi: slightly or markedly raised, may have irregular borders but are symmetric, center usually moe pigmented than periphery, increase in thickness and pigmentation:
Definition
Compound nevi
Term
Nevi: elevated, slightly or moderately pigmented, course dark terminal hairs may come from it:
Definition
intradermal nevi
Term
Nevi: sharply defined tan to brown patch containing several small monomorphic slightly raised dark brown nevi:
Definition
Nevus spilus
Term
nevi: solitary bluish macules usually on head & neck or buttock, present in early childhood or at birth
Definition
blue nevi
Term
nevi: reddish pink dome shaped smooth papule on face scalp or legs
Definition
spitz nevus
Term
Tx for spitz nevus:
Definition
excision
Term
preexisting nevus that develops a rim of hypopigmentation
Definition
halo nevi
Term
acquired brown hyperpigmentation of the face and neck durring 2nd or 3rd trimester of pregnancy and some women taking oral contraceptives:
Definition
Melasma
Term
Melasma Tx:
Definition
1. avoid sun
2. bleach creams
3. peels
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