Term
Fresh colored papules with rough surface
Due to HPV infection of keratinocytes |
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Definition
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Term
Firm, pink, umbilicated papules due to poxvirus
Keratinocytes show cytoplasmic inclusions |
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Definition
Molluscum contagiosum
Occurs in children and sexually active adults |
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Term
Sloughing of skin with erythematous rash and fever due to exfoliative A and B toxins.
Separation of the epidermis at the granulosum cell layer |
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Definition
| Staphylococcus scalded skin syndrome |
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Term
Deep dermal infection usually due to S. aureus or S. pyogenes
Can progress to necrotizing asciitis with necrosis of subcutaneous tissue due to fresh eating anaerobic bacteria (CO2 causes crepitus in tissue) |
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Definition
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Term
| Erythematous macules that progress to pustules, and crust over with a honey colored serum |
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Definition
Impetigo
(S. aureus or S. pyogenes) |
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Term
| Malignant melanoma differentiated from nevus with ABCD. What is ABCD? |
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Definition
Asymmetry
Border (irregular)
Color (not uniform)
Diameter (>6 mm) |
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Term
Tan to brown macule
Due to increased number of melanosomes (not melanocytes) |
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Definition
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Term
Congenital lack of pigmentation due to defect in tyrosinase enzyme.
Increased risk for Basal cell ca, Squamous cell ca, and melanoma |
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Definition
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Term
| Mask-like hyperpigmentation of the cheeks associated with pregnancy and oral contraceptives |
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Definition
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Term
| Actinic keratosis is a precursor lesion for this. Risk factors are exposure to UVB light |
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Definition
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Term
Presents as a elevated nodule with central ulcerated crator surrounded by dilated (telangiectatic) vessels
Pearly borders
Peripheral palisading on histology |
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Definition
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Term
Epidermal hyperplasia with darkening of skin with velvetly feel
Associated with non insulin dependent resistance or gastric malignancy |
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Definition
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Term
Squamous proliferation that appears stuck on
Has keratin pseudocysts (pearls)
Leser Trelat sign of underlying carcinoma of GI tract |
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Definition
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Term
Hypersensitivity reaction with targetoid rash (central clearing a result of necrosis)
Commonly associated with
HSV
Penicillin
Mycoplasma
SLE |
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Definition
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Term
Autoimmune deposition of IgA on the tips of the dermal papillae
Common in celiacs disease |
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Definition
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Term
Firm tense bullae do not rupture easily
Seperation of the entire epidermis from the dermis
Oral mucosa spared |
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Definition
Bullous pemphigus
Autoimmune destruction - IgG against hemidesmosomes |
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Term
IgG antibody against desmoglien 3
Tombstoning appearance on histology (basal cells still present on the basement membrane)
Separation of epidermis from dermis sparing the basal cells. |
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Definition
Pemphigus vulgaris
Type II hypersensitivity
Blisters rupture easily (nikolsky sign) |
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Term
Pruritic, planar, polygonal, purple papules
Histology shows inflammation of the dermal-epidermal junction with a saw tooth appearance |
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Definition
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Term
Acanthosis (epidermal hyperplasia)
Parakeratosis (corneum retains its nucleus)
Thinning of epidermis above the elongated dermal papillae (picking off will cause pinpoint bleeding = auspitz sign) |
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Definition
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Term
| Well circumscribed slamon colored plaques with silvery scale on extensor surfaces and scalp |
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Definition
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Term
| Propionibacterium acnes infection that produces lipases that breakdown excess sebum production |
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Definition
Acne vulgaris
tx: benzoyl peroxide
Vitamin A derivatives |
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Term
Pruritic erythematous rash with edema, arising from exposure to allergens
Type IV hypersensitivity reaction |
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Definition
Contact dermatitis
tx:
remove offending agent |
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Term
Pruritic erythematous oozing rash with vesicles and edema, face and flexor surfaces
Type I hypersensitivity |
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Definition
Atopic dermatitis (eczema)
Often associated with other atopy (asthma and allergic rhinitis) |
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Term
| Name all the cell layers of the skin and its associated parts |
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Definition
Epidermis:
Corneum
Lucidum
Granulosum
Spinosum
Basal
Dermal layer:
Blood vessels
Nerves
Hair follicles
Sweat glands |
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Term
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Definition
Acne Vulgaris
Propionibacterium Acnes |
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Definition
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Definition
Lichen Planus
Purple, polygonal, pruritic, papule |
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Definition
Pemphigus Vulgaris
Tombstoning |
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