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Anagen effluvium: chemotherapy Telogen effluvium: post partum, surgery, crash diet |
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Birbeck granules: (EM) characteristic intracytoplasmic organelles of langerhans cells (chief APC of epiderm) |
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Bullous pemphigoid: blisters auto-immune: IgG at DEJ |
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Dermal epidermal junction Hemidesmosomes: basal layer--base membr Lamina Lucida: anchoring filaments Lam Densa: hemides attach: lam5, IVcolag sublam Densa: epiderm--dermis, VII colag |
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Dermatitis herpetiformis Splitting of Lamina Lucida; IgA DEJ |
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Dermis elastica cutis laxa |
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Epidermolysis bullosa: blister formation following trauma; collagen VII Keratinocytes and DEJ |
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Epidermolysis bullosa: blister formation following trauma; Collagen VII Keratinocytes and DEJ |
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Hair follicle-Anagen: growing phase(90%) Growth 2-6 yrs (determines length) |
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Hair follicle- Catagen: Matrix cells stop dividing (<3%) Growth 2-3 wks |
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Hair follicle- Telogen: rest phase (10%) Growth 4 months ready to shed |
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Harlequin fetus: most severe ichthyosis Keratinocytes: Hyperkeratosis |
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Lamellar ichthyosis: X-linked Ichthyosis vulgaris: Auto-dominant Keratinocytes: hyperkeratosis |
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Langerhans histiocytosis Histiocytosis X: overgrowth |
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Oculocutaneous albinism tyrosinase defect:doesnt prod melanin Melanocytes |
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Piebaldism Failure of migration Melanocytes |
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Pilosebac folliculitis decalvans |
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Pilosebac hidradenitis suppurativa |
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Porphyria cutanea tarda disorder of heme synth: photoxicity DEJ |
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Vitiligo Melanocytes are destroyed |
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Allergic contact dermatitis |
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