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Dermatology
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40
Medical
Graduate
12/03/2011

Additional Medical Flashcards

 


 

Cards

Term

 erythromatous plaques, "silvery" scales in elbows, knees & scalp

Definition

PSORIASIS

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Plaque; Guttate; Inverse; Pustular; Erythrodermic; Psoriatic Arthritis

Term

 flushing, persistent erythema, telangiectasias & papules or pustules; Adult Caucasians

Definition

 

 

 

 

 

ROSACEA:

Erythromatotelangiectatic, Papulopustular, Phymatous, Ocular[image]

Term
  inflammatory exanthem, salmon-colored macules, patches or papules; "Christmas Tree" pattern. Women (15-40yrs) Spring & Autumn
Definition
PITYRIASIS ROSEA:[image]
Term

 scaling, red plaques of dermatitis in areas rich in pilosebasceous structures (Scalp, bearded region of face, genital regions, ear canal, paranasal, nasolabial) "Cradel Cap" in infants. Common in pts w/ Parkinson's, Cushings, HIV & Virilizing syndromes of women

Definition
SEBORRHEIC DERMATITIS:[image]
Term
 Pruritic, Purple, Polygonal, Papuls & Plaques. (in flexor surfaces of UE, genitalia & muc. mem)
Definition
LICHEN PLANUS:[image]
Term
  intense itching, well circumscribed red/violaceous to hyperpigmented lichenified, dry, scaly patches. "Leathery" appearance
Definition
NEURODERMATITIS/LICHEN SIMPLEX CHRONICUS:[image]
Term
common in hands, neck, eyelids, face, genitalia & legs. Erythema, vesicles & bullae, exudation from breaking of blisters, swelling & scaling. Linear vesicles & erythema = poison ivy/plant; type IV delayed hypersensitivity response
Definition
ALLERGIC CONTACT DERMATITIS: [image]
Term
 pitting edema, scaling, & cayenne peppery/hyperpigmented macules/pathces on the shins (often pruritic)
Definition
STASIS DERMATITIS: [image]
Term
macules or pathces w/ delicte sacling in UE & trunk in young adults who prespires freely. Lighter skin: lesions pink, yellow or brownish.Dark skin: hypopigmented (abnormally small melanosomes). Malassezia furfur dimorphic fungus (yeast phase: Pityrosporum ovale). DX: ziti & meat balls (KOH preparation)
Definition
TINEA VESICOLOR: [image]
Term


Tinea Corporis: ringworm, small papuls or papulo-vesicles, spread peripherally. Tendency for central clearing w/ red scaly papular borders

Tinea Cruris: erythematous to brwon pathces. Itching & burning complaints

Tinea manuum: Trichophyton Rubrum; can present "two feet & one hand"

Onychomycosis: thickened, lusterless, yellowish, friable nails; Trichophyton Rubrum

Definition
TINEA INFECTIONS: [image]
Term
 highly contagious; very pruritic. Small burrows, vesicles or papuls on hands. Papular pruritic lesions on penis scabies until proven otherwise. Sarcoptes scabie parasite.
Definition
SCABIES:[image]
Term
Pruritic urticarial papuls anywhere on body. "breakfast, lunch & dinner" bites. Cimex Lectularias bug. Do NOT live on humans.
Definition
BED BUGS: [image]
Term
 Type 1 HSV perioral areal; Type 2 HSV genital lesions; well defined, plaques, vesicles & ulcerated skin on baginal mucosa, penis or inner thigh. Latent phase in the dorsal root ganglia. Reactivated w/ stress. Tzanch preparation for dx.
Definition
HERPES SIMPLEX:[image]
Term
grouped vesicles on erythematous base; dermatomal pattern; erruption clears in 2-1/2 wks. Viral particles distributed to sensory ganglia for latent phase. Tzanck preparation for dx
Definition
HERPES ZOSTER: [image]
Term

most in children and yound adults

Verruca vulgaris: common wart; in hands, small black puncta on surface (seed)

Flat Wart: grouped, small slightly raised lesion; spread by shaving or scratching

Plantar Wart: on soles, lesions raised Y scaling

Condylomata acuminata: anogenital wart, soft, mooist cauliflower-like lesins

Definition
WARTS: [image]
Term
  single or multiple, discrete pustules or papules associated w/ hair follicles. An infxn from w/in follicle Y pilosebaceous unit by S. aureus.
Definition
FOLLICULITIS:[image]
Term
  pustules or small abscesses around the hair follicles & progress to dep inflammation ; red, tender, hard nodules; S. aureus pathogenic org. Commonly in post. neck, axillae, & buttocks
Definition
FURUNCLE/ CARBUNCLE (BOIL):[image]
Term
 most common type of drug rxn. Small pink to red macules & papules. Begins 7-14 days after drug exposure (second eruption 1-3 days)
Definition

 

MACULOPAPULAR/"MORBILIFORM" (EXANTHEM-LIKE):

[image]

Term

 Wheal, hive or welt is pink, levated, severly pruritic plaque; often annular. Caused by local edema w/in dermis. Antigen-IgE complexes stimulate mast cells. Type I hypersensitivity.

DERMOGRAPHISM: writing on skin, associated w/ urticaria


Definition

 

URTICARIA:

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Term
1+ annular or oval erythematous patches or edematous plaques (lips or genitalia). Du to systemic drug exposure; likely propagated by CD8+ T cells
Definition

 

FIXED DRUG ERUPTION:

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Term

  presents w/ prodorme of URI, fever & painful skin. Vesicles, bullae, erosion & hemorrhagic crusts of conjuctive, oral mucosa & genitalia.

SJS: <10% BSA

TEN: >30% BSA

Occurs 7-21 days after drug exposure (FATAL)

Definition

 

STEVENS-JOHNSON SYN (SJS)/TOXIC EPIDERMAL NECROLYSIS (TEN):

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Term


Acute: systemic; dsDNA antibodies; "butterfly" rash

Subacute cutaneous: anti-Ro antibodies; not systemic, very photosensitive, annular scaly erythematous pathces/papulosquamous rings

Discoid: inflammation > scarring; <10% systemic; on ears, face & neck scaly, brightly erythematous plaques > hypopigmentation

Definition

 

LUPUS ERYTHMATOUS:

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Term
 classic cutaneous lesions> heliotrope rash, shawls sign & Gottron's papules (erythematous scaly/lichenified papules/plaques over joints of hands). Autoimmune CT disease; +ANA; related to internal malignancy
Definition

 

DERMATOMYOSITIS:

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Term
Great imitator; "Lupus Pernio" facial lesion (red/brown non-scaly papules & nodules around the eyes, nose or mouth). Chest X-ray on anyone w/ skin lesions of sarcoid. Systemic dieases of noncaseating granulomas. Serum ACE will be elevated.
Definition

 

SARCOIDOSIS:

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Term
hematologic malignancy primarily in the skin; Mycosis Fungoides. Lesions: Patch(pink, slighlty scaly w/ epidermal atrophy), Plaque(raised, red, schaly lesion also on trunk), Tumors(formed when malignant T cells inaved dermis & subcutis) & Erythroderma/Sezary(malignant T-cell circulating in the blood).
Definition

 

CUTANEOUS T-CELL LYMPHOMA (CTCL):

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Term
 lesions start small red papulopustules & spontaneoulsy enlarge into painful ulcers (bullous). Pathergy: mild trauma to intact skin or active lesions causes extension of the ulcers. Associated w/ Crohn's, Ulcrative Colitis, RA, & Monoclonal IgA gammopathy. Do NOT Debride
Definition

 

PYODERMA GANGRENOSUM:

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Term
 depigmented maules or pathcs (hands, feet or face); unilater or symmetry. Patterns: Focal, Unilateral Segmental, Vulgaris, & Universal. Thought to be autoimmune; skin biopsy = absence of melanocytes. Folliculocentric if repigmentation.
Definition

 

VITILIGO:

[image]

Term
 autosomal dominants; cafe-au-lait macules (CALM), neurofibromas, frecking in the axillae & groin (Crowe's sign).
Definition

 

NEUROFIBROMATOSIS- TYPE 1 (NF1 gene on chromosome 17q11):

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Term
  autosomal dominant disorder w/ hypopigmented macules (ash leaf), facial angiofibromas (fibrous forehead plaque) collagenomas (shagreen patch), periungual fibromas (Koenen tumors), gingibal fibromas & dental enamel pits. Gene mutations: TSC1 (9q34; hamartic protein) and TSC2 (16p13; tuberin protein)
Definition

 

TUBEROUS SCLEROSIS:

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Term
acute self-limited inflammatory disorder of the skin & mucous membranes. Target Lesion: central papule w/ 2+ concntric erythematous rings. Reaction pattern secondary to HS infx (most commonly). DX: biopsy & culture.
Definition

 

ERYTHEMA MULTIFORME:

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Term

benign lesions in 4th decade; macular, papular or verrucous lesions; stuck on appearance.

Variants:

Dermatosis Papulosa Nigra: hyperpigmented on face of African Americans

Stucco Keratoses: gray/white on LE

Sign of Leser-Trelat: associated w/ internal malignancy

Definition

 

SEBORRHEIC KERATOSIS:

[image]

 

Term
Benign red to purple dome shaped paules (<1mm-1cm). In adulthood on trunk & extremities. Consist of dilated capillaries & postcapillary venules.
Definition
CHERRY ANGIOMA (ACQUIRED HEMANGIOMA):[image]
Term
Vascular lesion, bright red to reddish-brown, soft/firm, raised, pedunculated friable nodule. "Band-aid" sign. Children & Young Adults.
Definition

 

PYOGENIC GRANULOMA:

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Term

Well circumscribed, tan, brown or flesh colored macules, papules or plaques anywhere on body.

Junctional: flat discoloration

Intradermal: flesh colored, pink/tan papule

Compound: tan/brown, red/brown papule w/ histologic components of both junctional & intradermal

Definition

 

MELANOCYTIC NEVUS:

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Term
Brown papules/plaques, often HAIRY present at birth or by age 2. Small <1.5cm; Medium 1.5-20; Large/Giant >20cm "Bathing Suit Nevus"
Definition

 

CONGENITAL MELANOCYTIC NEVUS:

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Term
Have morphologic changes i.e. asymmetry, irregular border, color variation  (ABCDEs of melanoma). Usually on trunk. Can have increased risk for melanoma.
Definition

 

ATYPICAL NEVI (DYSPLASTIC NEVI) "Nevus w/ Architecture Disorder":

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Term
On sun damaged skin (head, neck, trunk & extremities). Rough, erythematous papule w/ white to yellow scare (patches/plaques). Pts. report tenderness; can evolve to SCC
Definition

 

ACTINIC KERATOSIS:

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Term

Pearly, shiny, yellowish (wax-like) nodule w/ a rolled edge & fine vascular pattern at edge. Center may be ulcerated. Commonly on forehead, nose, cheeks, upper lip, scalp & trunk.

Types: Nodular (most common), Superficial (rash-like), Morpheaform (scar-like), Micronodular & Pigmented

Definition

 

BASAL CELL CARCINOMA:

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Term

Lesions crusted & nodular. Commonly on face, cheek, ear, nose, forehead, dorsum of hand, lower lip or genitalia.

Variants:

Bowen's disease (in-situ)

Erythroplasia of Queyrat (in situ on penis)

Verrucous Carcinoma( associated w/ HPV)

Keratoacanthoma (fast growing; crater-like)

Definition

 

SQUAMOUS CELL CARCINOMA:

[image]

Term

Pigmented lesion.

ABCDE's: Asymmetry, Border irregularity, Color variation, Diameter ≥6mm & Evolving

Types: Superficial spreading (most common), Nodular, Lentigo maligna (elderly) & Acral lentiginous (dark skin).

Relationship w/ sun exposure!

Definition

 

MELANOMA:

[image]

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