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Definition
Atypical lymphocyte - large nucleus, finer chromatin, and abundant basophilic cytoplasm scalloping around adjacent cells |
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Band - mature nucleus with clumped chromatin but without segmentation |
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Basophil - large dark, red-purple basophilic granules that partially obscure the nucleus |
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Basophilic normoblast - chromatin condensation and deeply basophilic cytoplasm |
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Bone marrow mast cell - numerous uniform purple granules in the cytoplasm that partially obscure the nucleus |
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Dwarf megakaryocyte - bilobed nucleus, sometimes seen in the peripheral blood in MDS patients |
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Eosinophilic myelocyte - ovoid nucleus and eosinophilic secondary granules in the cytoplasm |
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Eosinophil - mature eosinophil with bilobed nucleus and large eosinophilic cytoplasmic granules (large chunky orange granules) |
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Definition
Large granular lymphocyte - has azurophilic cytoplasmic granules |
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Metamyelocyte - nuclear indentation and chromatin clumping (indentation is less than 1/2 the nucleus) |
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Monocyte - indented nucleus, linear "ropey" chromatin, basophilic "grey-blue" cytoplasm, and fine azurophilic crystals (red/purple/lilac) |
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Definition
Myeloblast - high N/C ration, fine chromatin, visible nucleoli, and basophilic cytoplasm (nucleus is less round than a pronormoblast) |
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Definition
Myelocytes - secondary cytoplasmic granules and condenstation of the nuclear chromatin. The myelocyte on the right is newer with persistent primary granules from the promyelocyte stage. |
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Definition
Orthochromatic normoblast - pyknotic nucleus and pink-gray cytoplasm |
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Plasma cells - abundant basophilic cytoplasm, eccentric nucleus, and perinuclear hoff (golgi apparatus). Denim blue jean colored. |
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Definition
Polychromatophilic normoblast - light blue cytoplasm due to the accumulation of hemoglobin |
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Promonocytes - linear "ropey" nuclear chromatin often with visible folds and basophilic cytoplasm that may contain vacuoles |
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Promyelocyte - azurophilic granules in the cytoplasm, the chromatin is still fine (cytoplasm still hasn't turned orange, just before the "dawn of neutrophilia") |
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Pronormoblast - large round nucleus, fine chromatin, and basophilic cytoplasm (like all erythroids the nucleus is just plain "round") |
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Definition
Reticulocyte - polychromatophilic erythrocyte with pink-gray cytoplasm due to residual RNA |
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Definition
Segmented neutrophil - multiple nuclear lobes joined by fine chromatin filaments (6 or more is abnormal = megaloblastic, or greater than 5% with 5 lobes) |
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Definition
Small lymphocyte - high N/C ration, condensed chromatin, and scant basophilic cytoplasm (nucleus can be cleaved) |
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