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DIT Quizzes Day 11
Male repro, toxicology
59
Other
Professional
05/23/2013

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Cards

Term
How is hnRNA processed before it leaves the nucleus?
Definition
5' cap
Poly-A tail
Splicing out of introns
Left with mRNA that leaves the nucleus
Term
What structures run through the cavernous sinus?
Definition
Ophthalmic and maxillary divisions of trigeminal, CNIII, CNIV, CNVI
Term
How do CO, BP, GFR, and Thyroid hormone change during pregnancy?
Definition
CO: increases by 30-50%
BP: decreases initially, lowest at 16wks,return to pre-pregnancy pressure at term
GFR: increases, BUN and Cr decrease
TH: no change
Term
What neoplasm is most commonly responsible for the following hormone paraneoplastic syndrome:
ACTH-->Cushing's syndrome
Definition
Small cell tumor of the lung
Term
What neoplasm is most commonly responsible for the following hormone paraneoplastic syndrome:
PTH-related peptide-->Hypercalcemia
Definition
Squamous cell cancers
Renal cell carcinoma
Breast cancer
Term
What neoplasm is most commonly responsible for the following hormone paraneoplastic syndrome:
Erythropoetin-->polycythemia
Definition
renal cell carcinoma
hemangioblastoma
hepatocellular carcinoma
pheochromocytoma
Term
What neoplasm is most commonly responsible for the following hormone paraneoplastic syndrome:
ADH-->SIADH
Definition
small cell lung cancer
any CNS disorder
Term
What are the stages of behavioral change
Definition
Precontemplation
Contemplation
Preparation/determination
Action
Maintenance
Term
Which skin disorder matches the following:
Pruritic, purple, polygonal papules
Definition
Lichen planus
Term
Which skin disorder matches the following:
Pruritic vesicles a/w celiac disease
Definition
Dermatitis Herpatiformis
Term
Which skin disorder matches the following:
Thick scar esp around the face/chest
Definition
Keloid
Term
Which skin disorder matches the following:
Parakeratotic scaling
Definition
Psoriasis
Term
Which skin disorder matches the following:
Keratin-filled cysts
Definition
Seborrheic keratosis
Term
Which skin disorder matches the following:
Skin rash and proximal muscle weakness
Definition
Dermatomyositis
Term
Which skin disorder matches the following:
Honey crusted lesions common about the nose and lips
Definition
Impetigo
Term
Which skin disorder matches the following:
Hyperkeratosis and koilocytes
Definition
HPV (Verrucae)
Term
What portion of the spinal cord is affected by tabes dorsalis?
Definition
Dorsal columns
Term
What portion of the spinal cord is affected by polio?
Definition
Anterior horn
Term
What is the treatment of choice for the following protozoa:
Trichomonas vaginalis
Definition
Metronidazole
Term
What is the treatment of choice for the following protozoa:
Trypanosoma cruzi
Definition
Nifurtimox
Term
What is the treatment of choice for the following protozoa:
Plasmodium vivax
Definition
Chloroquine + primaquine
Term
What is the treatment of choice for the following protozoa:
Leishmania donovani
Definition
Sodium Stibogluconate
Term
What is the treatment of choice for the following protozoa:
Entamoeba histolytica
Definition
Metronidazole and Iodoquinol
Term
What is the treatment of choice for the following protozoa:
Toxoplasma gondii
Definition
Sulfadiazine and pyrimethamine
Term
What enzyme is responsible for tRNA charging?
Definition
Aminoacyl tRNA synthetase
Term
What enzyme catalyzes peptide bond formation?
Definition
Peptidyl Transferase
Term
What are the characteristic sxx of HELLP syndrome?
Definition
Hemolysis
Elevated Liver enzymes
Low Platelets
Term
What testicular tumor is described in the following statement:
Composed of cytotrophoblasts and syncytiotrophoblasts
Definition
Choriocarcinoma
Term
What testicular tumor is described in the following statement:
Elevated AFP
Definition
Yolk sac tumor, embryonal carcinoma
Teratoma (50%)
Term
What testicular tumor is described in the following statement:
Elevated beta-hCG
Definition
Choriocarcinoma, embryonal carcinoma, teratoma (50%)
Term
What testicular tumor is described in the following statement:
Most common testicular tumor
Definition
Seminoma
Term
What testicular tumor is described in the following statement:
Most common testicular tumor in infants and up to 3 years old
Definition
Yolk sac tumor
Term
What testicular tumor is described in the following statement:
Most common testicular tumor in men over 60
Definition
Testicular lymphoma
Term
What testicular tumor is described in the following statement:
Histologic appearance similar to koilocytes (cytoplasmic clearing)
Definition
Seminoma
Term
What testicular tumor is described in the following statement:
Histology may have alveolar or tubular appearance sometimes with papillary convolutions
Definition
Embryonal carcinoma
Term
What testicular tumor is described in the following statement:
25% have cytoplasmic rod shaped crystaloids of Reinke
Definition
Leydig cell tumor
Term
What testicular tumor is described in the following statement:
Androgen producing and a/w precocious puberty
Definition
Leydig cell tumor
Term
A 55 year old male undergoing treatment for BPH has increased testosterone and decreased DHT as well as gynecomastia and edema. What is his medication?
Definition
Finasteride
Term
How does flutamide differ from finasteride?
Definition
Finasteride: 5a-reductase inhibitor used for BPH and male pattern baldness

Flutamide:nonsteroidal competitive inhibitor of androgens at the testosterone receptor used in prostate carcinoma
Term
What is the clinical use of clomiphene? How does it work?
Definition
Used to treat infertility and PCOS

Partial agonist at estrogen receptors in the hypothalamus. Prevents normal feeback inhibition and increases release of LH and FSH from pituitary, which stimulates ovulation
Term
What breast pathology fits the following description:
Most common breast mass in postmenopausal women
Definition
invasive ductal carcinoma
Term
What breast pathology fits the following description:
Most common form of breast cancer
Definition
invasive ductal carcinoma
Term
What breast pathology fits the following description:
Small, mobile, firm mass with sharp edges in a 24 year old woman
Definition
Fibroadenoma
Term
What breast pathology fits the following description:
Multiple bilateral fluid filled lesions with diffuse breast pain
Definition
Fibrocystic disease
Term
What breast pathology fits the following description:
Firm, fibrous mass in a 55 year old woman
Definition
invasive ductal carcinoma
Term
What are the side effects of sildenafil
Definition
Headache, flushing, dyspepsia, impaired blue-green color vision
Term
What is the role of Sertoli cells and Leydig cells in spermatogenesis
Definition
Sertoli cells support and nourish the developing spermatozoa (secrete adrogen binding protein)

Leydig cells secrete testosterone
Term
What is the difference between androgen insensitivity and 5a-reductase deficiency
Definition
Androgen insensitivity: testicular feminization; defect in DHT receptor-does not respond to stimulation; phenotypically normal females

5a-reductase deficiency:
can't convert testosterone to DHT
Ambiguous genitalia; at puberty, normal genitalia
Term
What is the most common cause of DIC
Definition
Sepsis, trauma, obstetric complications, pancreatitis
Malignancy
Nephrotic syndrome
Transfusion
Term
What is the most common heart murmur
Definition
Mitral valve prolaps
Term
What is the most common coronary artery involved in thrombosis
Definition
LAD
Term
What is the most common cause of death in lupus patients
Definition
Lupus nephropathy
Term
What is the most common congenital heart anomaly
Definition
VSD
Term
How many carbon molecules are found in testosterone and on androstendione?
Definition
19
Term
What structures develop from the mesonephric ducts?
Definition
Seminal vesicle, Epididymus, Ejaculatory duct, Ductus deferens
Term
What is the male homolog to the following female structure:
Vestibular bulb
Definition
Corpus cavernosum and corpus spongiosum
Term
What is the male homolog to the following female structure:
Labia minora
Definition
Ventral shaft of penis
Term
What is the male homolog to the following female structure:
Bartholin gland
Definition
Bulbourethral glands
Term
What is the male homolog to the following female structure:
Urethral and paraurethral glands
Definition
Prostate gland
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