Shared Flashcard Set

Details

Dosage Forms
Topical Delivery
15
Other
Professional
12/11/2008

Additional Other Flashcards

 


 

Cards

Term
Protectives
Definition
shield exposed skin surface from harmful stimuli
Term
Absorbents
Definition
absorb moisture from skin and local wounds to discourage bacterial growth
Term
Demulcents
Definition
can alleviate irritation of mucous membranes
Term
Emollients
Definition
fat or oil substances used to increase moisture content of skin membranes
Term
astringents
Definition
coagulate blood, help wounds and cuts heal quickly
Term
rubefacients
Definition
increase skin temperature by increasing circulation at the surface
Term
caustics
Definition
destroy skin at the applied site (warts, keratoses, hyperplastic tissue)
Term
keratolytics
Definition
cause peeling of skin, useful in the treatment of eczema, acne, etc.
Term
biological factors that effect absorption
Definition
skin age, skin condition, regional skin sites, skin metabolism, circulatory effects
Term
Physiochemical factors that effect absorption
Definition
skin hydration, drug/skin binding, temperature penetration enhancers, drug/vehicle interaction, dosage form properties
Term
three components of topical dosage form
Definition
base or body of dosage form, medicinal agent, preservative
Term
Ointments
Definition
intended for topical use, local effects, deliver drug to skin for dermal disorders
Term
types of ointment bases
Definition
1. hydrocarbon bases
2. absorption bases
3. emulsion bases (w/o)
4. emulsion bases (o/w)
5. water-miscible bases
Term
Characteristics of Hydrocarbon Bases for Ointments
Definition
* insoluble in water
* not water washable
* will not absorb water
* emollient
* occlusive
* greasy
Term
Examples of Hydrocarbon Bases
Definition
Petrolatum (vasoline), white petrolatum, yellow ointment
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