Term
|
Definition
|
|
Term
| Complications of Renal disease |
|
Definition
PAD
Neuropathy
Derm disorders
Psychosocial issues |
|
|
Term
| Derm manifestations of ESRD |
|
Definition
Acquired perforating dermatosis
Porphyria cutanea tarda
Calcinosis cutis
Calciphylaxis
Nephrogenic systemic fibrosis
Uremic pruritis
Foot ulcer |
|
|
Term
| Acquired perforating dermatosis |
|
Definition
characterized by transdermal elimination of material from dermis
Scattered cone shaped and plugged keratotic papules, plaques and nodules
Located in high friction areas - lower extremities most common
Lesions pink in fair skin, brown in darker skin |
|
|
Term
| Acquired perforating dermatosis - Treatment |
|
Definition
Potent corticosteroids
Topical or oral retinoids
Vitamin A
Keratolytics
UVB light therapy |
|
|
Term
|
Definition
Disorder of heme biosynthesis
Vesicles erupt in sun exposed areas
Not as common now bc iron overload in dialysis not as prevalent |
|
|
Term
| Porphyria Cutanea Tarda - treatment |
|
Definition
Manage iron overload
Minimize sun exposure
Minimize any photosynthesizing medication |
|
|
Term
|
Definition
Firm papules, plaques or nodules
Occasionally can exude white chalky substance
Found near joints or on fingertips
Treatment is management of calcium and phosphorus levels |
|
|
Term
|
Definition
Exact etiology unknown
Rare but can be fatal
High incidence in dialysis pts, hyperparathyroid pts and combined pts
Calcification and obstruction of small and medium cutaneous vessels
Hyperplasia of tunica media and tunica intima
Septal and/or lobular subcutaneous necrosis
All this leads to distal ischemia, painful ulcers and possible amputation |
|
|
Term
| Calciphylaxis - treatment |
|
Definition
Debridement and local wound care
Fibrinolytics
Hypophosphatemic diet
Calcitriol supplementation
Pain management - don't want to use NSAIDs due to kidney function and corticosteroids may make it worse |
|
|
Term
| Nephrogenic Systemic Fibrosis |
|
Definition
Seen in pts with ESRD with exposure to gadolinium (found in contrast)
usually see symptoms 2-4 weeks after exposure
Starts in LE first but moves to UE and trunk - spares the head
Bilateral fibrotic or brawny induration of the skin
Thickened indurated erythematous raised skin lesions
can lead to permanent contractions
Peau de orange appearance |
|
|
Term
|
Definition
Severe itching of the skin
Pathophysiology unclear
Excessive scratching leads to breaks in skin which may lead to infection
Nalfurafine and Naltrexone can be helpful to reduce itching |
|
|
Term
| Internation Working Group on the Diabetic Foot (IWGDF) Classification |
|
Definition
Used to assign risk for foot problems
Risk 0 - no recognizable risk factor
Risk 1 - neuropathy with no other risk factor
Risk 2 - PAD with or without neuropathy
Risk 3 - Current foot ulcer, Hx of foot ulcer or prior amputation |
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