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Drugs
Exam 1 Drugs
136
Agriculture
2nd Grade
02/03/2013

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Term
Diphenoxylate/atropine (Lomotil)
Definition
Opiate/Opiate derivative (Antimotility agent)
Term
Loperamide (Imodium)
Definition
Opiate/Opiate derivative (Antimotility agent)
Term
Polycarbophil (Fibercon)
Definition
Adsorbent
Term
Bismuth subsalicylate (Pepto Bismol, Kaopectate)
Definition
Anti-secretory Agent
Term
Lactobacillus
Definition
Bacterial replacement (used in diarrhea)
Term
Psyllium (Metamucil)
Definition
Bulk-forming Agent
Term
Methylcellulose (Citrucel)
Definition
Bulk-forming Agent
Term
Docusate sodium (Colace)
Definition
Stool Softener (Emollients)
Term
Polyethylene glycol (MiraLax)
Definition
Hyperosmotic
Term
Lactulose (Constulose)
Definition
Hyperosmotic
Term
Sorbitol
Definition
Osmotic Laxative
Term
Magnesium hydroxide (Milk of Magnesia)
Definition
Saline Laxative
Term
Magnesium citrate
Definition
Saline Laxative
Term
Sodium phosphate
Definition
Saline Laxative
Term
Prepopik
Definition
NEW stimulant + Osmotic Laxative
Term
Bisacodyl (Dulcolax)
Definition
Stimulant Laxative
Term
Senna
Definition
Stimulant Laxative
Term
Lubiprostone (Amitiza)
Definition
Chloride channel activator
Term
Linaclotide (Linzess)
Definition
guanylate cyclase-c agonist
Term
Methylnaltrexone (Relistor)
Definition
Peripherally acting mu-receptor antagonist
Term
Metoclopramide (Reglan)
Definition
Prokinetic
Term
Dolasetron (Anzemet)
Definition
5HT3 Inhibitor
Term
Granisetron (Kytril)
Definition
5HT3 Inhibitor
Term
Ondansetron (Zofran)
Definition
5HT3 Inhibitor
Term
Palonosetron (Aloxi)
Definition
5HT3 Inhibitor
Term
Aprepitant (Emend)
Definition
Highly selective substance-P/neurokinin-1 receptor antagonist
Term
Promethazine (Phenergan)
Definition
Phenothiazine derivative
Term
Prochlorperazine (Compazine)
Definition
Phenothiazine derivative
Term
Scopolamine (Transderm-Scop)
Definition
antagonizes acetylcholine at muscarinic receptors
Term
Dronabinol (Marinol)
Definition
Endogenous cannabinoid receptor agonist
Term
Meclizine (Antivert)
Definition
H1 antagonist; anticholinergic as well
Term
Dimenhydrinate (Dramamine)
Definition
55% diphenhydramine (H1 blocker); Anticholinergic effect
Term
Galanolactone
Definition
competitive antagonist at ileal 5-HT3 receptors
Term
Doxylamine (Unisom)
Definition
Pregnancy Category A, Antihistamine
Term
Metronidazole, amoxicillin, tetracycline, and clarithromycin; Bismuth subsalicylate (Pepto-Bismol) and PPIs
Definition
H. Pylori Eradications
Term
Omeprazole (Prilosec)
Definition
PPI
Term
Lansopraxole (prevacid)
Definition
PPI
Term
Dexlansoprazole (Dexilant)
Definition
PPI
Term
Rabeprazole (aciphex)
Definition
PPI
Term
Esomeprazole (nexium)
Definition
PPI
Term
Pantoprazole (protonix)
Definition
PPI
Term
Cimetidine (Tagamet)
Definition
Histamine-2 Receptor Antagonist
Term
Ranitidine (Zantac)
Definition
Histamine-2 Receptor Antagonist
Term
Famotidine (Pepcid)
Definition
Histamine-2 Receptor Antagonist
Term
Nizatidine (Axid)
Definition
Histamine-2 Receptor Antagonist
Term
Sucralfate (Carafate)
Definition
forms a paste-like barrier that adheres to the base of ulcer
Term
Misoprostol (Cytotec)
Definition
synthetic prostaglandin E2 analog that replaces protective prostaglandins
Term
Arthrotec
Definition
Dicofenac + Misoprostol
Term
Antacids
Definition
contain magnesium, aluminum, calcium carbonate, or sodium bicarbonate; buffering agents
Term
Sodium Alginate (Gaviscon)
Definition
reacts with sodium bicarbonate and saliva to form a viscous solution of sodium alginate
Term
Fidaxomicin
Definition
New drug to treat C. Difficile
Term
Ibuprofen, Naproxen, Ketoprofen, Diclofenac potassium, aspirin, acetaminophen/aspirin/caffeine
Definition
First line therapy; proven efficacy; Migraine Abortive Treatment
Term
Metoclopramide (Reglan) IV: Isometheptene and combinations
Definition
Antiemetic in Migraine Abortive Treatment
Term
Butorphanol nasal spray
Definition
Only agent with consistent migraine relief
Term
Sumatriptan
Definition
5HT Agonist
Term
Ergotamine
Definition
5HT(IB/ID) receptor: headache relief; 5HT (2A) receptor: generalized vasoconstriction
(not considered 1st line)
Term
DHE (Dihydroergotamine)
Definition
IV or Intranasal; good evidence for safety and efficacy; Contraindicated in Pregnancy
Term
Ergotamine Pearl
Definition
Ergotamine compounds with caffeine; improved absorption and potentiates pain relief properties
Term
Propranolol
Definition
DOC preventative migraine therapy
Term
Amitriptyline
Definition
1st line therapy; good choice for mixed tension/migraine headache
Term
Depakote
Definition
especially useful for pts w/ prolonged or atypical aura
Term
Methysergide
Definition
Limited use due to propensity for severe ADRs (migraine prevention)
Term
Verapamil
Definition
Delay of 1-2 months for effect (migraine prevention)
Term
Naproxen
Definition
Modest efficacy; good choice for menstrual migraines
Term
Topiramate
Definition
expensive; dimilar efficacy to propranolol
Term
Aspirin 500-100 mg
Definition
Best evidence abortive treatment of tension headache
Term
Acetaminophen
Definition
Less effective than NSAIDs; mixed results (abortive treatment of tension headache)
Term
Amitriptyline 75-150 mcg/day
Definition
DOC preventative for tension headaches (causes weight gain!)
Term
Tizanidine
Definition
alpha agonist; preventative for tension headaches; used in chronic type
Term
Mirtazapine and Botulinum toxin type A
Definition
preventative tension headache
Term
ergot compounds (inhalation only)
Definition
abortive treatment cluster headaches
Term
Verapamil
Definition
DOC preventative treatment cluster headaches
Term
Ergotamine
Definition
Good for short, mild cluster HA periods; DON'T COMBINE with triptans!
Term
Corticosteroids (HA)
Definition
quickly reduces number of attacks for episodic type cluster headaches
Term
Lithium
Definition
used for both chronic and episodic cluster headaches
Term
Long acting NSAIDs; Amitriptyline, Nausea medications
Definition
Prophylactic therapy for Medication Overuse Headache
Term
Albuterol (Cystic Fibrosis)
Definition
first med used in resp. treatment CF
Term
Hypertonic saline, then Pulmozyme (vest simultaneously)
Definition
second med used in resp. treatment CF
Term
Inhaled antibiotic
Definition
third med used in resp. treatment CF
Term
Steroid neb or inhaler
Definition
fourth med used in resp. treatment CF
Term
Pulmozyme (dornase alfa)
Definition
mucolytic; breaks up long DNA strands, decreases mucus viscosity
Term
Azithromycin (in CF)
Definition
studies show benefit for nutritional status and fewer pulmonary infections; monitor for atypical mycobacterium
Term
Ciprofloxacin (in CF)
Definition
Oral antipseudomonal antibiotic
Term
Tobramycin, Cayston, Colistimethate (in CF)
Definition
inhaled antipseudomonal antibiotic
Term
Penicillins, Cephalosporins, Carbapenems, Tobramycin, Ciprofloxacin, Aztreonam (in CF)
Definition
IV Antipseudomonal Antibiotics
Term
Bactrim (DOC)
Definition
Stenotrophomonas maltophilia and Burkholderia cepacia
Term
Ursodiol
Definition
Treats and prevents CF liver disease
Term
Periactin (cyproheptadine)
Definition
appetite stimulant
Term
Kalydeco (Ivacaftor)
Definition
indicated for CF patients > 6 years old with G441D mutation
Term
VX809
Definition
CFTR Corrector; facilitates movement of the CFTR protein to the cell surface
Term
Azmacort Aerosol, Intal MDI, Aerobid MDI, Primatene mist, Combivent MDI, Maxair Autohaler
Definition
Chlorofluorocarbons (CFCs) MDI sunset
Term
dry powder inhaler (DPI)
Definition
not for children < 4 years; limited expiration date once opened
Term
Albuterol
Definition
short acting beta 2 agonist inhalation; racemic mixture
Term
Levalbuterol
Definition
short acting beta 2 agonist inhalation
Term
Salmeterol; Formoterol
Definition
Long acting beta 2 agonist
Term
Formoterol (Foradil)
Definition
Long acting beta 2 agonist
Term
Ipratropium Bromide
Definition
competitive inhibition of muscarinic cholinergic receptors; Relief of acute exacerbations; used in addition to short actin beta 2 agonists
Term
Mexthylxanthines
Definition
Theophyline, aminophyline
Term
Theophyline, aminophyline
Definition
Altnerative additive long-term therapy (asthma) -- rarely used
Term
Fluticasone/salmeterol (Advair)
Definition
inhaled corticosteroid + long acting beta agonist
Term
Budesonide/formoterol (Symbicort)
Definition
inhaled corticosteroid + long acting beta agonist
Term
Mometasone/formoterol (Dulera)
Definition
inhaled corticosteroid + long acting beta agonist
Term
Cromolyn and Nedocromil (asthma)
Definition
alternative: long-term therapy; Prophylactic treatment; mast cell stabilizer
Term
Zafirlukast, Montelukast (Zileuton)
Definition
Alternative long term therapy; Leukotriene inhibitors
Term
Omalizumab (Xolar)
Definition
long term management for severe asthmatics (additive); persistent allergic asthma; poorly controlled asthma
Term
Brompheniramine, Chlorpheniramine, Clemastine, Diphenhydramine
Definition
Sedating Systemic Antihistamines
Term
Cetirizine, Fexofenadine, Levocetirizine, Loratadine, Desloratadine
Definition
Nonsedating Systemic Antihistamines
Term
Budesonide (Rhinocort)
Definition
Nasal Corticosteroid
Term
Beclomethasone dipropionate (Beconase AQ)
Definition
Nasal Corticosteroid
Term
Ciclesonide (omnaris)
Definition
Nasal Corticosteroid
Term
Pseudoephedrine and phenylephrine
Definition
systemic decongestants
Term
Oxymetazoline, Tetrahydrozoline, Xylometazoline
Definition
Topical decongestants (more rapid and effective than systemic)
Term
Cromolyn(Nasalcrom) OTC
Definition
Nasal Mast cell Stabilizer
Term
Azelastine and olopatadine
Definition
Intranasal Antihistamines
Term
ipratropium
Definition
intranasal anticholinergics
Term
Bepotastine, cromolyn, lodoxamide, nedocromil
Definition
mast cell stabilizers (ophthalmic)
Term
emedastine
Definition
ophthalmic antihistamine
Term
Alcaftadine, azelastine, epinastine, ketotifen, olopatadine
Definition
Mastcell stabilizer/antihistamines (ophthalmic)
Term
Naphazoline, oxymetazoline, phenylephrine, tetrahydrorzoline
Definition
Ophthalmic decongestants
Term
naphazoline/pheniramine maleate
Definition
ophthalmic decongestant/antihistamines
Term
ketorolac (Acular)
Definition
ophthalmic NSAID
Term
beta blockers, prostaglandin analogs, brimonidine, topical carbonic anhydrase inhibitors
Definition
1st line Treatment open-angle glaucoma
Term
pilocarpine, apraclonidine
Definition
2nd line treatment - open-angle glaucoma
Term
carbachol, oral carbonic anhydrase inhibitors, echothiophate
Definition
3rrd line treatment- open-angle glaucoma
Term
Betaxolol, Carteolol, Levobunolol, Metipranolol, Timolol
Definition
Beta blockers used in open-angle glaucoma
Term
Latanoprost, Tafluprost, Travoprost solutions
Definition
Synthetic prostaglandine F2alpha analogues (open angle glaucoma)
Term
Bimatoprost 0.03% (latisse, allergan)
Definition
open-angle glaucoma
Term
Apraclonide, Brimonidine, Brimonidine and Timolol
Definition
Adrenergic Agonists-selective for open-angle glaucoma
Term
Brinzolamide, dorzolamide, dorzolamide and timiolol
Definition
Carbonic anhydrase inhibitors (1st line; open angle glaucoma)
Term
carbachol and pilocarpine
Definition
cholinergic agonists direct acting (open angle glaucoma)
Term
Echothiophate
Definition
cholinesterase inhibitors (open angle glaucoma)
Term
ilocarpine, hyperosmotic, secretory inhibitor
Definition
used for Treatment (acute attack of closed-angle glaucoma)
Term
Antioxidant vitamins and minerals
Definition
treatment dry form macular degeneration
Term
Verteporfin
Definition
cytotoxic photosensitizing agent; treatment in wet form macular degeneration
Term
Vascular endothelial growth factor inhibtors
Definition
Aflibercept, pegaptanib, ranibizumab, bevacizumab--- injections for wet form macular degeneration
Term
Angiogenesis inhibitors
Definition
treatment in wet form macular degeneration
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