Shared Flashcard Set

Details

ehoovey
oncogenes, tumor suppressor genes, and tumor markers
25
Other
Not Applicable
06/04/2006

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Cards

Term
c-myc
Definition
Burkitt's lymphoma
Term
bcl-2
Definition
Follicular and undifferentiated lymphomas (inhibits apoptosis)
Term
erb-B2
Definition
breast, ovarian, and gastric carcinoma
Term
ras
Definition
colon carcinoma
Term
L-myc
Definition
Lung tumor
Term
N-myc
Definition
Neuroblastoma
Term
ret
Definition
MEN II and MEN III
Term
Rb
Definition
13q, retinoblastoma, osteosarcoma
Term
BRCA1 and 2
Definition
17q, 13q, breast and ovarian cancer
Term
p53
Definition
17p, most human cancers, Li-Fraumeni syndrome
Term
APC
Definition
5q, colorectal cancer
Term
WT1
Definition
11q, Wilm's tumor
Term
NF1
Definition
17q, Neurofibromatosis type 1
Term
NF2
Definition
22q, Neurofibromatosis type 2
Term
DPC
Definition
18q, pancreatic cancer
Term
DCC
Definition
18q, colon cancer
Term
PSA
Definition
prostate-specific antigen. prostatic carcinoma
Term
CEA
Definition
carcinoembyronic antigen. very nonspecific but producted by 70% of colorectal and pancreatic cancers; also produced by gastric and breast carcinomas
Term
alpha-fetoprotein
Definition
normally made by feus. hepatocellular carcinomas. nonseminomatous germ cell tumors of the testis.
Term
beta-hCG
Definition
Hyaditidiform moles, Choriocarcinomas, and Gestational trophoblastic tumors.
Term
CA-125
Definition
ovarian, malignant epithelial tumors
Term
S-100
Definition
melanoma, neural tumors, astrocytomas
Term
alkaline phosphatase
Definition
metastases to bone, obstructive biliary disease, Paget's disease of bone
Term
Bombesin
Definition
neuroblastoma, lung and gastric cancer
Term
TRAP
Definition
tartrate-resistant acid phosphatase. hairy cell leukemia - a B-cell neoplasm
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