Term
| ACE inhibitors will cause what teratogenically? |
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Definition
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Term
| Alcohol will cause what teratogenically? |
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Definition
| fetal alcohol syndrome, malformations, developmental retardation, microencephaly, holoporsencephaly, face abnormal, limb dislocation, heart and lung fistulae |
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Term
| Alkylating agents will cause what teratogenically? |
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Definition
| Absence of digits and multiple other anomalies |
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Term
| Aminoglycosides will cause what teratogenically? |
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Definition
| CN VIII 8 toxicity, deafness |
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Term
| Cocaine will cause what teratogenically? |
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Definition
| Cocaine addiction at birth, placenta abruption, abnormal development. It is a potent vasoconstrictor which cuts off blood flow to developing organs causing agenisis/atresias (such as GI atresia) |
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Term
| Diethylstillbestrol (DES) will cause what teratogenically? |
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Definition
| Vaginal clear cell adenocarcinoma |
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Term
| Iodide either lack or excess will cause what teratogenically? |
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Definition
| Congenital goiter or hypothyroidism |
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Term
| Lithium will cause what teratogenically? |
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Definition
| Ebstein's anomaly of atrialized right ventricle (R vent is tiny, R atria is huge, valves are displaced toward the apex on R side) |
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Term
| Maternal diabetes will cause what teratogenically? |
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Definition
| Caudal regression syndrome (anal atresia / sirenomelia) (mermaid looking w/o feet/legs) |
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Term
| Tobacco smoking (nicotine or carbon monoxide) will cause what teratogenically? |
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Definition
| Preterm labor, placental issues, ADHD, IUGR (intra uterine growth restriction = small slow grow babies) |
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Term
| Tetracyclines will cause what teratogenically? |
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Definition
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Term
| Valproate will cause what teratogenically? |
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Definition
| Inhibition of intestinal folate adsorption = NTDs |
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Term
| Retinol Vit A excess will cause what teratogenically? |
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Definition
| High risk for spontaneous abortion, defects (cardiac and cleft palate) |
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Term
| Warfarin will cause what teratogenically? |
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Definition
| Bone deformities, fetal hemorrhage, abortion |
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Term
| X-rays (radiation), and anticonvulsants will cause what teratogenically? |
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Definition
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Term
| What process failed when there is one vagina and cervix, but there are essentially two uteruses? |
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Definition
| the Paramesonephric ducts failed to fuse. This is a bicorunate uterus (partially septate uteus w/ single cervix/vagina) Normally they fuse to form uterine tubes, uterus cervix, and 1/3 vagina. Failure along there can cause at worst two separate uterine horns, cervixes, and two separate vaginas. |
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