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Embryology
Test 1
50
Biology
Graduate
10/04/2009

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Term
What animal was the person (from 50 years ago) associated with
Definition
toad
Term
Loosely connected cells that act independantely in the embryo are referred to as?
Definition
mesenchyme
Term
Name one historical dev. biologist from at lest 50 years ago.
Definition
Spallanzani
Term
Give an example of a substrate adhesion molecule
Definition
Fibronectin
Term
Cellular communication involving actual contact is called?
Definition
juxtacrine
Term
The phenomena of nuclear transcript being processed such that exons might be treated as introns desribes post-translational control mechanism referred to as?
Definition
differential RNA splicing
Term
As cells pass through the final stage of commitment in dev., their prospective potency will become equal to their?
Definition
prospective significance
Term
The ability of the grex slime mold to change the fate of cells dependant on their location within the slug is referred to as?
Definition
conditional specification
Term
When only some of the mRNA's transcribed in a nucleus are transported into the cytoplasm, this is an example of?
Definition
differential RNA selection
Term
If cell adhesions between cells AA are greater than BB or AB, then A celss will sort to?
Definition
The center
Term
The fundamental component of chromatin composed of histones and DNA is called the?
Definition
nucleosomes
Term
Proposed by Yves Delage in 1895, the ultimate test of genetic constancy was achieved in 1997 by?
Definition
somatic cell nucleur transplant. George Campbell and DOLLY
Term
A differentiated cell will still share two charecteristics with all other differentiated cells. One of these is?
Definition
Stable
Term
Tethering of a transmembrane cadherin molecule to actin microfilaments in the cell cytoplasm requires?
Definition
catenins
Term
An example of a molecule that confers ability to respond to an induction event is?
Definition
Pax-6
Term
In chromatin, the composite structure made up of 140 base pairs of DNA wrapped around a octamer core of histones is called a?
Definition
nucleosome
Term
A polypeptide produced in the sertoli cells that gives negative feedback to the anterior pituitary
Definition
inhibin
Term
Give an example of a signal transduction pathway that is based on the receptor tyrosine kinase (RTK) model
Definition
SMAD
Term
The phenomena of nuclear transcript being processed such that exons might be treated as introns describes a post-translational control mechanism referred to as?
Definition
differential RNA splicing
Term
This large molecule is frequently found between cells and functions as a spacer to create cell-free areas for migrations.
Definition
Proteoglycan aggregate
Term
Dark bands in polytene chromosomes represent regions of chromosomal DNA incapable of transcription and are called?
Definition
Heterochromatin
Term
Give an example of a non-flagellated sperm.
Definition
roundworm sperm
Term
The single most important distinguishing charecteristic of a differentiated cell is its?
Definition
Biochemistry
Term
Production site of GDNF in the male?
Definition
sertoli cells
Term
A type of molecule composed of linear repeating chains of dissaccharides of which one contains an amino group.
Definition
glycosamminoglycan (GAG)
Term
An example of a juxtacrine signal transduction pathway would be?
Definition
Notch pathway
Term
ATPase enzyme attached to the A tubule of a typical flagellar axoneme?
Definition
dynein arm
Term
Type of specification that is based on cytoplasmic interactions prior to cellurization?
Definition
syncytial specification
Term
Type of cell migration dependant on chemical gradients in solution
Definition
chemotaxis
Term
Name one molecule found in a signaling pathway that serves double duty in another cellular process or function that is not directly involved in signaling?
Definition
b-catenin?
Term
Metezoan animals that normally form the anal region 2nd during gastrulation?
Definition
protozome
Term
Sperm undergo differentiation during the phase of gametogenesis called?
Definition
spermiogenesis
Term
Cells that form sheets and tubes are referred to as?
Definition
epithelial cells
Term
Increased DNA compaction is achieved in sperm by the histon like protein?
Definition
protamines
Term
The first spermatogenic cells that are haploid are
Definition
2ndary spermatocytes
Term
Term for the orignal stem cell line from which gonial cells are derived in all sexes?
Definition
primordial germ cells
Term
Differential distribution of the bicoid and nanos mRNA in the Drosophila egg prior to fertilization is achieved by?

microfilaments
modifications of the 3' UTR
modification of the 5' poly A tail
tethering proteins in the oocyte membrane
modification of the 5' UTR
Definition
modifications of the 3' UTR
Term
In eukaryotic organisms, RNA transcript sequences that don't code for the AA sequence of a protein are called?

enhancers
promoters
exons
introns
mutations
Definition
introns
Term
Which pair is correctly matched?

SMAD4 - juxtacrine receptor
Notch - juxtacrine receptor
JakStat - dependent on integrin recept.
BMP4 - hedgehog family
TGF-B - initiates presenilin1
Definition
Notch - juxtacrine receptor
Term
Kinase mediated activation of specific signal transducers and activators of transcription induced by the production of dimerized receptors is a charecteristic of?
Definition
JakStat signal transduction pathway
Term
The premise that clones are destined to premature death because of shortened telomeres was disproved by?

Wilmut
Yanagimachi
Spemann
Definition
Yanagimachi
Term
Growth in which shape changes b/c components grow at the dfferent rates?
Definition
allometric
Term
Which of the following terms are related to an animal with regulative type development?
Definition
cell fate will change dependant on their location in the embryo
Term
Which of the following represents an incorrect hormone target cell interaction in a male mammal?

FSH on sertoli cells
GDNF on spermatogonia
LH on Leydig
LH on thecal cells
inhibin on AP
Definition
LH on thecal cells
Term
The teratogen-like plant alkaloids jervine and cyclopamine generate cyclopia in vertebrates by inhibiting synthesis of this compound
Definition
cholesterol
Term
We talked about Pax6 protein being necessary for imparting competence to certain tissues involved in induction of the lens of the eye. Which of the following techniques would be most helpful in determining the spatial and temporal production of the RNA responsible for PAx6 production?

in situ hybridiztion
polymerase chain reaction
zenoplastic transplants of the optic cup
Definition
In situ hybridization
Term
In a generalized model of receptor tyrosine kinase pathways one could expect

multiple endpoints
cascade of kinase mediated events
activation of dormant transcription factors
phospohrylation at a tyrosine residue on an inactive molecule
all of above
Definition
all of above
Term
CC the cat clone of Rainbow is strong correlative evidence for?

selective nuclear mRNA processing
post-translational control of gene expression
deactivation of an entire chromosome
Definition
deactivation of an entire chromosome
Term
Why will sponges dissociate in Ca reduced seawater but not in Mg reduced seawater?
Definition
Cadherin binding and Ca binding sites. Ca important for cell adhesion.
Term
Differential gene expression from enetically identical nuclei creates different cell types. What are three major levels at which gene expression might be controlled and give one example of each.
Definition
transcription - alterations of RTK pwy

nuclear RNA processing - introns are spliced for activation

mRNA translation - induction

post-translational modifications
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