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endo test 2 meds
nova PA orlando
61
Medical
Graduate
01/24/2010

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Cards

Term
Onset of Lispro/Aspart
Definition
5-15 min
Term
Peak Action of Lispro/Aspart
Definition
1-1.5 hrs
Term
Effective Duration of Lispro/Aspart
Definition
3-4 hrs
Term
Onset of Regular Insulin
Definition
30-60 min
Term
Peak action of Regular insulin
Definition
2 hrs
Term
Effective duration of Regular insulin
Definition
6-8 hrs
Term
Onset of NPH/Lente
Definition
2-4 hrs
Term
Peak action of NPH/Lente
Definition
6-7 hrs
Term
Effective duration of NPH/Lente
Definition
10-20 hrs
Term
Onset of Lantus/Ultralente
Definition
1.5 hrs
Term
Peak action of Lantus/Ultralente
Definition
flat
Term
Effective duration of Lantus/Ultralente
Definition
24 hrs
Term
very rapid acting insulin
Definition
lispro/aspart
Term
short acting insulin
Definition
human regular
Term
intermediate acting insulin
Definition
Human NPH or Lente
Term
Long acting insulin
Definition
Lantus/Ultralente
Term
blood sugar of 60-110
Definition
no insulin
Term
blood sugar of 111-150
Definition
2 units of insulin
Term
blood sugar of 151-200
Definition
4 units of insulin
Term
blood sugar of 201-250
Definition
6 units of insulin
Term
blood sugar of 251-300
Definition
8 units of insulin
Term
blood sugar of 301-350
Definition
10 units of insulin
Term
blood sugar >350
Definition
12 units of insulin, call MD
Term
order of meds given to hypoglycemic pt
Definition
1. glucose granules
2. glucose tablet
3. OJ
4. candy
5. glycagon injection
Term
MOA of sulfonylureas
Definition
stimulate insulin release from pancreatic B cells
Term
sulfonylureas
Definition
Chlorpropamide (Diabinese), Glyburide (Glynase/Micronase), Glipizide (Glucotrol)
Term
dosage of Chlorpropamide/diabinese
Definition
250 mg/day, max dose 500 mg/day
Term
SE of Chlorpropamide/diabinese
Definition
jaundice, hypoglycemia
Term
DOA of Chlorpropamide/diabinese
Definition
60 hrs
Term
Contraindications of Chlorpropamide/diabinese
Definition
sulfa allergy, DKA
Term
dosage of glyburide/glynase/micronase
Definition
starting dose 2.5 mg/day, average maintenance dose 5-10 mg/day, max dose 10 mg/day
Term
DOA of glyburide/glynase/micronase
Definition
24 hrs
Term
Contraindications of glyburide/glynase/micronase
Definition
cirrhosis (b/c it is metabolized in the liver), sulfa allergy, DKA
Term
dosage of glimepiride (amaryl)
Definition
starting dose: 1 mg/ day, max dose 8 mg/day
Term
DOA of glimepiride (amaryl)
Definition
24 hrs
Term
SE of glimepiride (amaryl)
Definition
hyponatremia
Term
contraindications of glimepiride (amaryl)
Definition
alcoholism, sulfa allergy
Term
pt. education for glimepiride (amaryl)
Definition
electrolytes need to be done with every visit
Term
glipizide/ glucotrol dosage
Definition
5-15 mg in the morning, max dose 15/mg/dose
Term
SE of glipizide/ glucotrol
Definition
SIADH
Term
contraindications of glipizide/ glucotrol
Definition
pregnancy, sulfa allergy
Term
pt. education for glipizide/ glucotrol
Definition
do not chew, crush, or cut this med
do CBC, LFTs, renal fxn, LDH, alkaline phosphate tests on a regular basis
Term
Biguanides
Definition
metformin/glucophage
Term
metformin
Definition
most useful in DM pts. who are obese and have increased insulin levels
Term
dosage of metformin
Definition
500 mg TID with meals, max dose 2000 mg
Term
half life of metformin
Definition
1.5-3 hours
Term
SE of metformin
Definition
lactic acidosis, GI symptoms
Term
contraindications of metformin
Definition
serum creatinine greater than or equal to 1.5 mg/dl, alcoholism, hepatic insufficiency
Term
MOA of metformin
Definition
primary action is on the liver reducing hepatic gluconeogenesis
Term
TZDs
Definition
pioglitazone/ actos
Term
dosage of pioglitazone/actos
Definition
15-45 mg/day, do NOT take with food
Term
DOA of pioglitazone/actos
Definition
24 hrs
Term
SE of pioglitazone/actos
Definition
dec. bone density, ovulation in post menopausal women, peripheral edema
Term
contraindications of pioglitazone/actos
Definition
NY AHA class III or IV cardiac status, active liver ds, ALT levels greater than 2.5x upper limits of normal
Term
pt. education for pioglitazone/actos
Definition
husband should get vasectomy
Term
MOA of pioglitazone/actos
Definition
sensitizes peripheral tissue to insulin
Term
dosage of acarbose/precose
Definition
starting dose 50 mg BID, then increase to 100 mg TID, take with 1st mouthful of food
Term
SE of acarbose/precose
Definition
GI discomfort, flatulence, diarrhea
Term
contraindications of acarbose/precose
Definition
colonic ulcers, malabsorption syndrome, intestinal ds, cirrhosis
Term
MOA of acarbose/precose
Definition
competitively inhibits alpha-glucosidase enzymes in the GI tract that digest starch and sucrose
Term
alpha-glucosidase inhibitors
Definition
acarbose/precose
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