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Endocrinology
Melatonin... The Pineal Gland
13
Veterinary Medicine
Professional
11/14/2010

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Cards

Term
Where is melatonin produced?
Definition
The pineal gland
Term
Explain the synthesis of melatonin.
Definition
1. Photo info from retina
2. suprachiasmatic nucleus
3. hypothalamus
4. SNS via the superior cervial ganglion
5. pineal gland
Term
What is the affect of dark on melatonin?
Definition
Stimulator.
1.NE released
2. increases alpha1 and beta1 receptors in pineal gland
3. increases cAMP and Ca
4. convert Serotonin --> Melatonin
Term
How does light inhibit melatonin secretion?
Definition
retinal cells cannot release NE
Term
What controls the circadian rhythm?
Definition
suprachismatic nucleus
Term
True or False
Melatonin can have positive effects on symptoms of jet lag.
Definition
True
Term
What melatonin receptor regulates retinal function, circadian rhythm and reproduction
Definition
High Affinity (ML1)
Term
What are actions of melatonin that are not receptor mediated?
Definition
1. Free radical scavenger
2. at pharmalogical doses
3. immune system agumentation
Term
How is sleep affected by melatonin?
Definition
speed of falling asleep
duration and quality of sleep
hypnotic effects
Term
How are melatonin and mood asscoiated?
Definition
Depression and SAD may be casued by low or delayed levels of melatonin secretion.
Term
True or False
Melatonin can stimulate progesterone synthesis.
Definition
True
Term
True or False.
Melatonin secretion decreases with aging.
Definition
true
Term
True or False.
Melatonin inhibits tumorigenesis caused by
Definition
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