Term
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Definition
| external cues that influence rhythmicity of hormone secretion |
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Term
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Definition
-pacemaker for circadian rhythms
-cluster of nerve cell bodies above optic chiasm in hypothalmus |
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Term
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Definition
| hormone response element that binds to a region of DNA in the nucleus. |
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Term
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Definition
| 1 hormone must be present in adequate amounts for the full effect of another hormone. (Testosterone increases # of EPI receptors so that EPI can have full effect) |
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Term
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Definition
| combined effect is greater than the sum of separate efforts (T and FSH together for optimal sperm production) |
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Term
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Definition
| when 1 hormone causes the down-regulation of another hormone's receptors (P causes loss of E receptors on uterine sm muscle to prevent contractions until labor) |
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Term
| Causes of Hormone Deficiency |
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Definition
-autoimmune dz
-surg
-mutations in hormone, receptors, tr. factors, enzyme channels |
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Term
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Definition
-ectopic tumor
-autoimmune dz
-excess hormone admin during tx |
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Term
| Causes of hormone resistance |
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Definition
-defect in receptor or signal transduction pathway
-defective hormone actions despite increased levels |
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Term
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Definition
| molecules that bind to the receptor and BLOCK binding of agonist; failure to trigger intracellular signaling events |
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