Term
| where is angiotnesinogen produced? |
|
Definition
|
|
Term
| what is the rate limitng step of the RAS system |
|
Definition
| Angiontensinogen -> ANg I by renin |
|
|
Term
| where is angiotenin I formed? |
|
Definition
|
|
Term
| what is the active peptide of RAS? |
|
Definition
|
|
Term
|
Definition
endothelial cells
circulating in blood |
|
|
Term
| where is angiotensin II formed? |
|
Definition
|
|
Term
| what causes macula densa to increase renin? |
|
Definition
| increased NaCL in filtrate |
|
|
Term
| what causes intrarenal baroreceptor to increase renin? |
|
Definition
| decrease in affervent arteriole pressure |
|
|
Term
| what causes B-adrenergic receptor pathway to increase renin? |
|
Definition
| activation of B1 recpt on juxtoglomerulus cells |
|
|
Term
| if macula densa senses high Na what does it do? |
|
Definition
constrict afervent
decrease filtration |
|
|
Term
| short loop feedback for renin? |
|
Definition
| angiotensin II recpt on juxtoglomerulus |
|
|
Term
| long term negativ eloop for renin? |
|
Definition
macula densa- increase Na secretion by increasing filtration
barorectptor- increase BP in affervent arteriole
B adrenerginic- decrease Ne, decrease activaiton |
|
|
Term
| which angiotenin II recpt is a vasporessur |
|
Definition
|
|
Term
| what type of recpt are angiontenisn II? |
|
Definition
|
|
Term
effect of ANG II on:
vasculature |
|
Definition
constriciotn
smooth muscle hypertrophy |
|
|
Term
effect of ANG II on:
adrenal cortex |
|
Definition
|
|
Term
effect of ANG II on:
adrenal medula |
|
Definition
|
|
Term
effect of ANG II on:
kidney -3 |
|
Definition
effervent constriction
inhibit renin
increase Na reabsorption |
|
|
Term
effect of ANG II on:
heart-2 |
|
Definition
miocardial hypertrophy
collegen synth |
|
|
Term
effect of ANG II on:
brain: |
|
Definition
release of vasopression ADH
thirst and salt appetite
increase central sympathetic |
|
|
