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Exercise Implications
Applied Patho Final
53
Other
Graduate
12/05/2008

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Term
ACUTE systemic inflammation signs and symptoms
Definition
fever, tachycardia, hypermetabolic state, elevated WBC/C-reactive protein/amyloid A
Term
CHRONIC systemic inflammation signs and symptoms
Definition
low-grade fever, malaise, weight loss, anemia, elevated WBC and ESR
Term
systemic factors influencing healing
Definition
nutritional status (protein and vit C), psychological wellness, co-morbidities (CVD, DM, cancer)
Term
what does water do in the body?
Definition
provides for nutrition delivery to cells, provides for excretion of waste products, promotes energy production, promote cellular function
Term
Fluid Volume Deficit
Definition
loss of either fluid or electrolyte w/ loss of volume; excessive loss or inadequate intake, (sodium is a major ion b/c water follow sodium), can cause hypervolemia or dehydration, severe deficit can cause vascular collapse and shock
Term
PT issues w/ fluid deficit
Definition
1% dec. leads to drop in exs performance and capacity; 2% dec. will drop VO2 max significantly; HR inc. 6 bpm for each 1% drop; be aware of risk factors and clinical S&S
Term
PT issues w/ dehydration
Definition
dec. CO; absent perspiration, tearing, salivation; confusion, disorientation, cognitive issues; dizziness when standing, orthostatic intolerance; loss of coordination, irritability, lethargy; headache; rapid pulse and respirations
Term
PT issues w/ fluid imbalance
Definition
know pt food/drink status; provide small vol. of fluid freq.; water maybe conraindicated in HF or RF pts; caffeine and alcohol are diuretics
Term
Elderly risk factors for fluid imbalance...
Definition
acute illness, bowel cleansing, mental status, excessive (calcium) intake, laxatives, diuretics, sodium restricted diets, voluntary fluid restriction, incontinence, obesity (low water %)
Term
PT skin care implications for fluid excess
Definition
edematous tissue is very fragile, skin stretch beyond normal limits, limited blood supply, heals poorly, eliminate friction, treat edema
Term
PT implications for electrolyte imbalances
Definition
muscle weakness and wasting, tetany, bone pain, COGNITIVE changes, skin changes, neuromuscular irritability (m. fatigue/twitching/cramping), edema, vital signs (tachycardia, orthostasis, inc. respiration)
Term
Effects of sodium on the body
Definition
affects osmolality, influences blood vol/MAP/interstitial fluid vol, changes ECF, linkedto forms of genetic HTN, balance linked to potassium balance, dec. in salt intake will dec. water intake, inc. in salt output will inc. urine vol
Term
Hyponatremia S&S
Definition
muscle cramps, weakness, headache, depression, personality changes, lethargy, edema
Term
Hypernatremia S&S
Definition
dry skin, headache, agitation, dec. reflexes, seizures, tachycardia
Term
Potassium effects on the body
Definition
required for normal Na/K pump, eseential for normal muscle contraction/relaxation, imbalance leads to altered muscular activity
Term
Hypokalemia (low K+) S&S
Definition
fatigue, muscle cramping, cardiac arrythmias (dizziness, palpitations), orthostatic hypotension
Term
Calcium effects on the body
Definition
influences cell membrane permeability, regulates neuromuscular activity, key role in cardiac cell conduction and in myocardial and vascular cell contractions, affects bone/kidney/GI tract
Term
Hypocalcemia
Definition
convulsions, memory impairment, delusions, hallucinations, paresthesia, muscle cramps, tetany
Term
Hypercalcemia
Definition
drowsiness, weakness, confusion, irritability, lethargy
Term
Magnesium effects on the body
Definition
neuromuscular integration, stimulates PTH secretion and affects Ca++, influences skeletal muscle contraction, role in ATP production, affects musculoskeletal and cardiac systems
Term
PT care for pt w/ electrolyte imbalance
Definition
support adherence to dietary restrictions, encourage activity, frequent position changes, monitor vital (and ECG if possible), safety issues
Term
which 3 systems act indep. to maintain normal plasma pH?
Definition
blood buffer system, lungs, kidneys
Term
PT implications for acid/base imbalances
Definition
be aware of S&S, watch for pulmonary/CV/renal changes, burns, fever, sepsis, DM, vomiting/diarrhea-chronic, elderly & mechanically ventilated pts, help facilitate breathing (freq. turning, deep breathing tech., coughing), help pts w/ relaxation and control
Term
Respiratory acidosis
Definition
DEC. neural excitability, restlessness, sleepiness, headache, weakness, cyanosis, dec. pH, inc. HCO3
Term
Respiratory alkalosis
Definition
INC. neural excitability, dizziness, tetany, N/T, seizures, inc. pH, dec. HCO3
Term
Metabolic acidosis (kidney problem)
Definition
muscle twitching, weakness, malaise, vomiting, headache, low pH, low bicarbonate
Term
Metabolic alkalosis (kidney problem)
Definition
nausea, confusion, irritability, agitation, twitching, cramping, convulsions, high pH, high bicarbonate
Term
general causes of acute renal failure
Definition
problem w/ filtering mech, tubule, or blood flow: acute shut down in renal fxn, dec. blood flow to the kidney, disruptions in the kidney structure, postrenal disruption in urine elimination
Term
Acute glomerular nephritis causes (acute inflamm subsides in 2 wks)
Definition
intrinsic, damage to glomerulus, ischemic or toxic origin, streptococci, antibodies reacting against kidneys, immune complexes are trapped, glomeruli blocked, inflamm. response, normal glomeruli become permeable to protein and RBC
Term
Acute tubular necrosis causes
Definition
destruction of tubular epithelial cells, ischemia (circ. shock, tubular cells die and slough off, nephrons plugged, no urine output), nephrotoxic drugs (Hg, lead, tetracyclines; blakc casts occur in urine), toxins from an infection, pts w/ surgery/hypovolemia/sepsis/trauma/burns
Term
Acute emboli causes
Definition
emboli or atherosclerosis in renal arteries or afferent arterioles, reduced blood flow to glomerulus, red. GFR and urine output, below 20% normal blood flow to renal tubule cells cause hypoxia, may cause cell death
Term
chronic renal failure disorders
Definition
glomerulonephritis, pyelonephritis, benign nephrosclerosis
Term
glomerulonephritis
Definition
progressive, follows SLE or acute failure, progressive thickening of basement membrane, invasion of fibrous tissue, capillary coefficient becomes reduced, reduced filtration
Term
pyelonephritis
Definition
bacterial infection, E.Coli, obstruction of urine outflow, effects renal medulla interstitium, fxnal units lost
Term
benign nephrosclerosis
Definition
very common, causes assoc. w/ HTN and DM, Afr. Am at inc. risk, fibrinoid deposits, occluded vessels, fibrous tissue, glomerulosclerosis, progressive dec. in blood flow and GFR, vicious cycle
Term
End stage renal disease
Definition
loss of 90% kidney fxn, GFR <5% of normal, uremia, scarring of glomeruli, atrophy and fibrosis of kidney tubules, dep. on dialysis or transplantation, caused by HTN/DM/chronic glomerulonephritis/obstruction
Term
PT implications on dialysis
Definition
prolonged NSAID use, weakness and fatigue, cognitive changes, anemia/weakness and red. fxnal capacity after dialysis, exercise effects on BMD, evaluate muscle strength (catabolism/anorexia), uremia (mixed sensory and motor neuropathy), measure bp in arm opposite the AV shunt for dialysis
Term
Progression to ESRD (end stage renal disease)
Definition
1. dec. renal reserve-hypertrophy of normal nephrons; GFR 50% of normal
2. chronic renal insufficiency-azotemia (N waste in blood), anemia, HTN, GFR 20-35% of normal
3. chronic renal failure-poor vol and electrolyte regulation leading to edema, metabolic acidosis, hypercalcemia, neuro/CV/GI symptoms, GFR 20-25% of normal
4. ESRD-virtually all body systems involved
Term
Kidney disease pts
Definition
have inc. protein degradation but are not hypermetabolic; energy expenditure at rest and w/ phys act is same as normal in nondialyzed and maintenance hemodialysis people
Term
Clinical signs important for PTs in kidney disease pts
Definition
peripheral neuropathies (LE>UE, atrophy and demyelination possibly due to uremic toxins, central problems: red. alertness, memory, red. conc.); dialysis site has a peritoneal catheter and fistula so don't put BP cuff on that arm
Term
Exercise and dialysis
Definition
exs during dialysis improves efficiency of dialysis but is difficult w/ the equip, circuit training recommended to inc. strength and endurance, pts can inc. exercise capacity by 20-40% and improve lipid profile and glucose metabolism
Term
Exercise precautions for dialysis pts
Definition
be sure pt is medically stable (K levels), monitor BP, inc. fatigue occurs after dialysis but exs is not contraindicated at this time, pt may be less stable metabolically the day before dialysis so the best day to exs is the day after, use RPE scale, red. isometric or static exs effects on BP and inc. afterload on heart by having pt breathe on exertion and use a resistance that can be completed in one smooth motion
Term
Contraindications for exercise in dialysis pts
Definition
BP > 200/120, valsalva
Term
Exercise and ESRD
Definition
low exercise capacity (20% less VO2), autonomic dysfxn (HR response limited, use RPE for intensity); training improves VO2 max by about 40%, improves CV risk factors/QOL/autonomic dysfxn, controls BP and DM; caution: may exacerbate co-morbidity and K levels must always be stable before exercising
Term
Exercise modes and prescriptions for ESRD
Definition
modes: bike, no swimming, resistance exs
prescription: 4-6 days/wk, low duration (2 min of exs, then 1 min rest, up to 30 min continuous), use RPE to det. intensity
Term
S&S of GI Disease
Definition
N/V, anorexia, constipation, dysphagia, heartburn, GI bleeding; assoc. w/ exs (diarrhea, ab cramps, belching, nausea, heartburn)
Term
PT implications for GI pts
Definition
postural hypotension (excessive fluid loss, caution w/ upright posture, orthostatic testing, monitor vitals); upper quadrant screening (diff. swallowing, forward head posture, disc protrusion)
Term
Hiatal Hernia PT implications (lower esophogeal sphincter weakness so part of stomach rises above diaphragm)
Definition
avoid flat supine pos., avoid exs req. valsalva, avoid inc. in abd and thoracic pressures, promote wt. loss, progressive exs 6-8 wks post surgery, chest tube considerations
Term
Crohn's Dz and ulcerative colitis S&S
Definition
constant crampy ab pain (R lower quadr), R lower quadr ab mass, low grade fever, fistula formation, small freq. stools, rectal bleeding, anorexia and wt. loss, dehydration, tachycardia
Term
Medical tx for crohn's and ulcerative colitis
Definition
antiinflamm drugs, antibiotics, fluids and dietary restrictions, activity limitations in acute phase, surgical resection
Term
PT interventions for GI
Definition
optimize fxnal mobility, max activity tolerance and endurance, prevent p/o pulm complications via deep breathing and IS, malabsorption and anemia may be limiting factors, consult w/ nutritionist about caloric intake
Term
Liver disease (cirrhosis) S&S
Definition
GI symptoms, jaundice, portal hypertension, tremors, ab edema (ascites), RUQ pain, fever, GI bleeding, altered mental status, esophageal varices
Term
PT implications for liver cirrhosis
Definition
rest and reduce metabolic demand, resistance exs to prevent bone loss, prevent muscle loss, avoid supine and valsalva, bronchial hygiene and pulmonary PT, pain management via pos. changes, deep breathing, coughing, incision splinting, and early mob.
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