Term
What potentially deadly tx is indicated for LTBI? What is the danger of this tx? |
|
Definition
***rifampin + pza. substitute refabutin w/hiv pts. USE W/CAUTION. don't use w/underlying liver dz, hepatoxic meds. stop tx or sx alt/ast elevation, asx elevation over 5uln or any bilirubin elevation |
|
|
Term
What is the preferred regimen for ltbi? |
|
Definition
|
|
Term
When are steroids used for tb? |
|
Definition
meningitis, pericardial tb |
|
|
Term
|
Definition
|
|
Term
what tb tx causes hepatitis, hyperuricemia, arthropathy? |
|
Definition
|
|
Term
what tb tx causes optic neuritis? |
|
Definition
|
|
Term
what tb tx causes renal and 8th n toxicity? |
|
Definition
|
|
Term
what tb tx causes uveitis, red-orange discoloration of bodily fluids, flu syndrome, thrombocytopenia, hepatitis, p450 induction- pi's? |
|
Definition
rifamycin. rifampin worse than rifabutin |
|
|
Term
what tb tx causes uveitis, red-orange discoloration of bodily fluids, flu syndrome, thrombocytopenia, hepatitis, p450 induction- pi's? |
|
Definition
rifamycin. rifampin worse than rifabutin |
|
|
Term
what tb tx has se: hepatic toxicity, acidosis, seizures? |
|
Definition
|
|
Term
what are 2 rapid direct tests for tb? |
|
Definition
mtd- transcription mediated or dna amplification tests |
|
|
Term
what tb tx has excellent absorption and penetration into body fluids and cavities, most rapidly bactericidal? |
|
Definition
|
|
Term
how do you tx isoniazid od? |
|
Definition
|
|
Term
what tb tx is bactericidal, well absorbed, penetrate inflamed meninges? to what does it bind? |
|
Definition
rifamycins, bind dna dependent rna polymerase |
|
|
Term
what tb tx is absolutely necessary for a 6 mo short course regimen? |
|
Definition
|
|
Term
what extrapulmonary tb sx has local manifestations including f infertility? |
|
Definition
|
|
Term
what type of tx is encouraged for tb maintenance phase? |
|
Definition
intermittent tx (2/3x/week) |
|
|
Term
what tb test is an in vitro t cell based assay? what are 2 methods? |
|
Definition
whole blood interferon-gamma assay. elisa, elispot |
|
|
Term
right sided heart disease |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
cough. (dyspnea also present) |
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
peak p deep s wave, rv hypertrophy, supraventricular arrhythmia |
|
Definition
|
|
Term
|
Definition
|
|
Term
more potent long-term copd bronchodilaters |
|
Definition
anticholinergics more than beta-adrenergics. ipratropium bromide (atrovent), tiotropium bromide (spiriva) |
|
|
Term
cromolyn (intal) and nedocromil (tilade) |
|
Definition
long acting bronchodilators |
|
|
Term
salmeterol (serevent) and formoterol (foradil) |
|
Definition
long acting beta agonists |
|
|
Term
less than 2days/week and less than 2 nights/mo |
|
Definition
|
|
Term
2-7 days/week, more than 2nights/mo |
|
Definition
|
|
Term
daily, more than 1 night/week |
|
Definition
moderate persistent step 3 |
|
|
Term
continual daily, frequent night |
|
Definition
|
|
Term
|
Definition
prednisone/methylpredinisone |
|
|
Term
|
Definition
|
|