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Extra Pulmonary Flashcards
Clinical Medicine Module 4
34
Medical
Graduate
07/14/2009

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Cards

Term
What potentially deadly tx is indicated for LTBI? What is the danger of this tx?
Definition
***rifampin + pza. substitute refabutin w/hiv pts. USE W/CAUTION. don't use w/underlying liver dz, hepatoxic meds. stop tx or sx alt/ast elevation, asx elevation over 5uln or any bilirubin elevation
Term
What is the preferred regimen for ltbi?
Definition
inh + b6 for 9 mos
Term
When are steroids used for tb?
Definition
meningitis, pericardial tb
Term
tb tx
Definition
inh/rif/pza + etm or sm
Term
what tb tx causes hepatitis, hyperuricemia, arthropathy?
Definition
pyrazinamide
Term
what tb tx causes optic neuritis?
Definition
ethambutol
Term
what tb tx causes renal and 8th n toxicity?
Definition
streptomycin
Term
what tb tx causes uveitis, red-orange discoloration of bodily fluids, flu syndrome, thrombocytopenia, hepatitis, p450 induction- pi's?
Definition
rifamycin. rifampin worse than rifabutin
Term
what tb tx causes uveitis, red-orange discoloration of bodily fluids, flu syndrome, thrombocytopenia, hepatitis, p450 induction- pi's?
Definition
rifamycin. rifampin worse than rifabutin
Term
what tb tx has se: hepatic toxicity, acidosis, seizures?
Definition
isoniazid
Term
what are 2 rapid direct tests for tb?
Definition
mtd- transcription mediated or dna amplification tests
Term
what tb tx has excellent absorption and penetration into body fluids and cavities, most rapidly bactericidal?
Definition
isoniazid
Term
how do you tx isoniazid od?
Definition
pyridoxine
Term
what tb tx is bactericidal, well absorbed, penetrate inflamed meninges? to what does it bind?
Definition
rifamycins, bind dna dependent rna polymerase
Term
what tb tx is absolutely necessary for a 6 mo short course regimen?
Definition
rifamycins
Term
what extrapulmonary tb sx has local manifestations including f infertility?
Definition
genitourinary
Term
what type of tx is encouraged for tb maintenance phase?
Definition
intermittent tx (2/3x/week)
Term
what tb test is an in vitro t cell based assay? what are 2 methods?
Definition
whole blood interferon-gamma assay. elisa, elispot
Term
right sided heart disease
Definition
carcinoid
Term
neuroendocrine tumor
Definition
carcinoid, sclc
Term
most common lung ca sx
Definition
cough. (dyspnea also present)
Term
pe most common sx
Definition
tachypnea
Term
st abnormalities
Definition
pe, cor pulmonale
Term
peak p deep s wave, rv hypertrophy, supraventricular arrhythmia
Definition
cor pulmonale
Term
baclofen
Definition
mm relaxant, singultus
Term
more potent long-term copd bronchodilaters
Definition
anticholinergics more than beta-adrenergics. ipratropium bromide (atrovent), tiotropium bromide (spiriva)
Term
cromolyn (intal) and nedocromil (tilade)
Definition
long acting bronchodilators
Term
salmeterol (serevent) and formoterol (foradil)
Definition
long acting beta agonists
Term
less than 2days/week and less than 2 nights/mo
Definition
mild intermittent step 1
Term
2-7 days/week, more than 2nights/mo
Definition
mild persistent step 2
Term
daily, more than 1 night/week
Definition
moderate persistent step 3
Term
continual daily, frequent night
Definition
severe persistent step 4
Term
tx pulmonary vasculitis
Definition
prednisone/methylpredinisone
Term
tx sarcoidosis
Definition
prednisone
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