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Extracellular Messengers
Dr. Spencer
11
Biochemistry
Graduate
12/16/2010

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Cards

Term
4 types of first messengers
Definition
-Neurotransmitters
-Hormones
-Growth Factors
-Cytokines
Term
Neurotransmitter Characteristics
Definition
Small, hydrophillic,short range, and have excitatory or inhibitory action depending on receptor
Term
hormone characterisitics
Definition
Diverse group of molecules(amino acid derivatives, small peptides, proteins, lipid derivatives)
-long range, and are released only to provoke a specific response from target cells
Term
Why are hydrophobic hormones relatively small?
Definition
Because they are mostly diffusing through membranes, and in order to do this they need to be small
Term
in General what size are hydrophillic hormones?
Definition
range from small to extremely large
Term
What hydrophobic hormone is classified as a local hormone which is associated with paracrine function?
Definition
prostaglandins.
Term
Examples of hydrophillic hormones
Definition
Substituted amines,peptides
Term
Hydrophobic hormones
Definition
prostaglandins, steroids, retinoids
Term
Growth Factor characterisitics
Definition
More than 50 proteins used in the paracrine and autocrine system, functioning in cell growth and differentiation
Term
cytokine characteristics
Definition
more than 80 large proteins in the paracrine and autocrine system taht work in the coordination of the immune response
Term
examples of cytokines
Definition
interleukins, interferons, TNFalpha and beta
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