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Farm Animal Repro Part 2
n/a
100
Agriculture
Undergraduate 4
11/13/2011

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Cards

Term
When ovulated, the egg comes out of which side of the follicle?
Definition
opposite side it was attached to
Term
Proestrus is characterized by an increase in which hormone?
Definition
estradiol/ estrogen
Term
When is P4 high and E2 low in the estrous cycle?
Definition
diestrus
Term

Ovulation occurs at the beginning of metestus(in general).

true or false?

Definition
true
Term
In Louisiana, what is the range for estrus in cows?
Definition
6-14 hours
Term
What is the length of a cycle in humans?
Definition
28 days
Term
What is the cycle length in the mouse and rat?
Definition
4-5 days
Term
Why do mice and rats have short cycle lengths?
Definition
They don't form a CL unless they mate, this increases the rate of pregnancy because they have excluded the luteal tissue.
Term
What are the uterine phases in humans?
Definition

Menstrual flow- lining of uterus is shed

Proliferative phase- follicular growth and growth of lining is stimulated by E2

Secretory phase- P4 and E2 thicken the lining of the uterus so embryo can implant

Term

In humans, the CL secretes estrogen.

true or false?

Definition
true
Term
Estrogen causes the LH peak, but what causes the production of estrogen?
Definition
the follicle as it gets bigger
Term
What are the sex steroids in females?
Definition

progesterone

estrogen

Term
How can you extend the length of the cycle?
Definition
Injecting P4 day 12-14
Term
What is the male sex  steroid?
Definition
testosterone
Term
What are the 2 protein hormones involved in repro?
Definition

LH

FSH

Term
What does FSH do?
Definition
stimulates the growth of the follicle
Term
When does ovulation occur in humans (ave.)?
Definition
day 14.5 of the cycle
Term
What is menarch? And what is the average age when this happens?
Definition

Age when young females start to cycle.

12.7 years

Term
What is the mean age of menopause?
Definition
51.4 years
Term

In the cow, the embryo develops on the opposite side of the CL.

true or false?

Definition
false, the embryo develops on the same side as the CL
Term
What must the embryo produce so that the mother doesn't abort it?
Definition
antiluteolytic factor
Term
What does luteolytic factor do and where does it come from?
Definition
It causes the regression of the CL and comes from the uterus
Term
If a cow isn't pregnant, what hormone will she produce to cause regression of the CL?
Definition
PGF2 alpha
Term
What happens during the Counter-Current Mechanism?
Definition
PGF2alpha is released from the uterine horn →goes into vascular system → uterine vein → ovarian artery → ovary → cause luteal regression
Term
In 1972, prostaglandins were made from __
Definition
sponges
Term
If pregnant, counter-current mechanism will happen unless the baby produces the antiluteolytic factor to stop the regression of the CL. In essence, what is this called?
Definition
Maternal recognition
Term
Which farm animal has the most developed counter-current mechanism and which has the least developed?
Definition

Most developed- cow and sheep

Least developed- horse

Term
What hormone could you inject a cow with to cause luteal regression?
Definition
PGF2alpha
Term
What must you do before injecting a cow with PGF2alpha?
Definition
Make sure she isn't pregnant! She'll abort if she is.
Term
On which days will injecting with PGF2alpha not work? Why?
Definition

Won't work on days 1-5 , because CL isn't functioning on these days

Won't work on days 16-20, because CL is already regressing on its own

Term
If this is given to a pregnant pig on day 110 of gestation it will cause parturition.
Definition
PGF2alpha
Term
PGF2alpha is derived from this fatty acid
Definition
arachidonic acid
Term
How many carbons does PGF2alpha have?
Definition
20
Term
Where is the oxytocin produced that causes luteal regression?
Definition
Produced in the large lutean cells of the CL
Term
If given an oxytocin blocking agent, what will happen?
Definition
The cycle will last longer
Term
How does the CL cause its own demise?
Definition
It produces oxytocin which binds to the receptor on the endometrium. Arachidonic acid is converted to PGF2alpha by PG Synthetase. PGF2alpha leaves the endometrium and causes the CL to regress
Term
What is EPSI?
Definition

Endometrial Prostaglandin Synthetase Inhibitor

Antiluteolytic Factor

Term
What is another name for bTP(bovine trophoblastic protein-1)?
Definition
Interferon Tau
Term
Where does EPSI come from?
Definition
It's produced by the placenta
Term
How does Interferon Tau block the regression of the CL?
Definition
bTP-1 is released from the embryo which binds to the receptor on the endometrial wall. This causes the release of EPSI which then inhibits the conversion of arachidonic acid to PGF2alpha
Term
In the mare, the embryo enters the uterus through the UTJ and then rolls around the uterus and produces a substance like bTP-1 but is called P-19. What is this movement called?
Definition
embryo mobility response
Term

Even though oxytocin enhances the birth process, you don't want to inject a pig with it until the first piglet is born. If you do, this will cause the cervix to close and blow out a uterine horn.

true or false?

Definition
true
Term
How many embryos must a pig have to keep a pregnancy?
Definition
at least 4
Term
Which piglets will be the biggest?
Definition
The first and last piglet
Term
A follicle that is mature is called a ___
Definition
Graafian folllicle
Term
From which layers of the follicle are the steroid hormones produced?
Definition

Theca interna

Granulosa layer

Term
What is the name of the fluid inside the follicle? (English and Latin name)
Definition

Antrum

liquor folliculi

Term
How are majority of the hormones regulated?
Definition
Negative feedback
Term
How do LH and FSH produce the steroid hormones?
Definition
LH hooks to LH receptors, causes enzymatic pathways to change progesterone to testosterone. FSH then causes testosterone to change to estradiol which goes out into circulation.
Term
If gave an agent to block FSH receptors, what will increase in the bloodstream?
Definition
testosterone
Term
Where does FSH convert testosterone to estradiol?
Definition
granulosa cells
Term
Where does LH convert progesterone to testosterone?
Definition
Theca interna cells
Term
What is the progression from cholesterol to estradiol?
Definition
Cholesterol→ Pregnenolone→ Progesterone→ Testosterone→ Estradiol
Term
What is DES?
Definition
Diethylstilbestrol
Term
What plant hormone has a similar structure to estradiol?
Definition
genistein
Term
What is the adenohypophysis?
Definition
anterior lobe or pars distalis
Term
What are the other two names for the posterior pituitary?
Definition
Neurohypophysis or pars nervosa
Term

The posterior pituitary develops from Rathke's Pouch.

true or false?

Definition
false, the anterior pituitary develops from Rathke's Pouch
Term
What is the name of the depression in the sphenoid bone that protects the posterior and anterior lobes?
Definition
sella turcica
Term
What are the two peptide hormones released from the posterior pituitary?
Definition
ADH and oxytocin
Term
ADH?
Definition
antidiuretic hormone
Term
This hormone is involved in the synthesis of milk
Definition
prolactin
Term
What is the mechanism for milk let-down?
Definition
Oxytocin released from posterior pituitary causes the epithelial cells of the alveoli to contract in the mammary gland
Term

Peptide hormones are larger than protein hormones.

true or false?

Definition
false, peptide hormones are smaller than protein hormones
Term
What is the name of the system of veins that are involved in the Neuroendocrine Arc?
Definition
Hypophyseal Portal Veins
Term
Bypassing blood is taken away by the __
Definition
Tubecular Artery
Term
Which hormone(peptide) causes an increase in thyroid function?
Definition
TRH
Term
Which peptide hormone can increase peak LH and cause cow to ovulate?
Definition
GnRH
Term
What does ADH do?
Definition
Regulates water volume of the blood
Term
What is another name for Growth Hormone?
Definition
somatotropin
Term
What hormone could you inject a cow with to increase milk production?
Definition
GH/ somatotropin
Term
What causes the release of FSH and LH?
Definition
GnRH
Term

Oxytocin and ADH aren't made in the posterior pituitary, they are stored here.

true or false?

Definition
true
Term
GnRH, TRH, CRH, STH-RH, PIH, PRH, and Somatostatin are all peptide hormones produced by what?
Definition
hypothalamus
Term
The anterior pituitary mainly produces which type of hormones?
Definition
protein hormones
Term
What do human pregnancy tests measure?
Definition
hCG
Term

eCG?

What's the old name?

Definition

equine chorionic gonadotropin

PMSG- Pregnant Mare Serum Gonadotropin

Term
This potent substance, as a mare goes into later trimester, will disappear from the bloodstream.
Definition
eCG
Term
This small protein inhibits the output of FSH
Definition
Inhibin
Term
This hormone causes a female to prepare for parturition
Definition
Relaxin
Term
Where does the brain stimulus go in the Neuroendocrine Arc?
Definition
the supraoptic nuclei cell and the paraventricular nuclei cell
Term
This center has rapid high intense impulses and is related to the LH peak
Definition
surge center
Term
This center sends out little impulses over longer periods of time
Definition
tonic center
Term
What can stress do to a cow right before she ovulates?
Definition
Will cause a decrese in GnRH therefore will cause a lower LH peak
Term
An increase in the concentration of hormones can do what?
Definition
Increase response
Term

Steroid hormones are lipid soluble, therefore they can go in and out of cells.

true or false?

Definition
true
Term
Does hormone concentration have a proportional effect on negative feedback?
Definition
Yes, increase the hormone concetration, increase feedback
Term
This surge causes the female to come into estrus and also causes the LH peak.
Definition
Estrogen surge
Term
Where does the E2 surge come from?
Definition
follicle
Term
(cow) Estrogen surge to estrus= ___ hours
Definition
18
Term
(cow) E2 surge to LH peak= ___ hours
Definition
20-25
Term
(cow) Onset of estrus to LH peak= ___ hours
Definition
2-5
Term
(cow) LH peak to ovulation= ___ hours
Definition
25-30
Term
E2 has small peaks during ___.
Definition
metaphase
Term
(humans) LH peak to ovulation= ___ hours
Definition
36-40
Term
Cats are what type of ovulators?
Definition
induced
Term
When do cats ovulate?
Definition
30 hours after mating
Term
A male cat has a penis that protrudes to the rear with these on it that can lock it into place near the cervix.
Definition
barbules
Term
Other than cats, what other animals are induced ovulators?
Definition
llamas, rabbits
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