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Final Exam
Immune System
21
Biology
Undergraduate 1
05/17/2010

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Term
nonspecific defenses
Definition
first line of defense, skin, mucus, hair
Term
phagocytic cells: monocytes, natural killer cells
Definition
engulf bacteria and viruses
monocyes-give rise to macrophages
natural killer cells-attack cancer cells and virus-infected cells by releasing chemicals
Term
interferons
Definition
proteins produced by virus infected cells that signal other cells to produce proteins that interfere with virus prouction
Term
complement protein
Definition
cut lethal holes in invaders and amplify inflammatory response
Term
inflammatory response
Definition
nonspecific, damaged cells release histamine, causes blood vessels to dilate, plasma leaks, phagocytes move out, platelets leak out and seal off infected region and area becomes warm, red, swollen
Term
lymphatic
Definition
battleground during infection, lymph nodes have white blood cells and kill invaders
Term
specific defenses
Definition
recognize antigens (antibody generator)
relies on signal from a foreign antigen
antibodies attach to antigen and make it easier for phagocytes to eat
Term
active immunity vs passive
Definition
active-body produces antibodies following exposure to an antigen
passive
receieve antibodies from mother (temporary)
Term
lymphocytes orginate
Definition
bone marrow
Term
B cells vs T cells
Definition
B=bone and antibodies=humoral immunity
T=thymus=cell mediated immunity
Term
antigenic determinants (unique)
Definition
antiven receptors bind to specific antigens at specific locations
Term
exposure to antigen for first time
Definition
B cells produce specific antibodies (survive few days)
produce clones of cells iwth memory (may last a lifetime)
Term
humeral defense
Definition
antibodies mark antigens for elimination, specific recognition phase, nonspecific destruction phase
Term
B and T cell
Definition
B attack invaders in blood, lymph
T attack invaders of cells
Term
helper T cells vs cytotoxic t cells
Definition
helper t-release interleukins-makes tcell grow and divide-memory, stimulates B cell humeral response and activity of cytotoxic t cells
Term
cyotoxic t cells
Definition
kill infected body cells by producing perforin tht punches hole in cell membrane
Term
autoimmune diseases
Definition
immune system fails to recognize self proteins and mounts immune against tissue
ex: lupus, insulin dependent diabetes,multiple sclerosis
Term
immunodeficiency diseases
Definition
lack components of immune system
Term
AIDS
Definition
hiv infects helper t ells that results in immune system attacking itself
Term
thermoregulation
Definition
endotherms derive heat from metabolism
exoterms derive heat from environment
Term
excretory system
Definition
helps maintain balance of water and salt in blood and body fluids
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