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first line of defense, skin, mucus, hair |
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phagocytic cells: monocytes, natural killer cells |
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engulf bacteria and viruses monocyes-give rise to macrophages natural killer cells-attack cancer cells and virus-infected cells by releasing chemicals |
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proteins produced by virus infected cells that signal other cells to produce proteins that interfere with virus prouction |
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cut lethal holes in invaders and amplify inflammatory response |
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nonspecific, damaged cells release histamine, causes blood vessels to dilate, plasma leaks, phagocytes move out, platelets leak out and seal off infected region and area becomes warm, red, swollen |
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battleground during infection, lymph nodes have white blood cells and kill invaders |
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recognize antigens (antibody generator) relies on signal from a foreign antigen antibodies attach to antigen and make it easier for phagocytes to eat |
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active immunity vs passive |
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active-body produces antibodies following exposure to an antigen passive receieve antibodies from mother (temporary) |
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B=bone and antibodies=humoral immunity T=thymus=cell mediated immunity |
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antigenic determinants (unique) |
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Definition
antiven receptors bind to specific antigens at specific locations |
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exposure to antigen for first time |
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Definition
B cells produce specific antibodies (survive few days) produce clones of cells iwth memory (may last a lifetime) |
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Definition
antibodies mark antigens for elimination, specific recognition phase, nonspecific destruction phase |
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B attack invaders in blood, lymph T attack invaders of cells |
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helper T cells vs cytotoxic t cells |
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helper t-release interleukins-makes tcell grow and divide-memory, stimulates B cell humeral response and activity of cytotoxic t cells |
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Definition
kill infected body cells by producing perforin tht punches hole in cell membrane |
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Term
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Definition
immune system fails to recognize self proteins and mounts immune against tissue ex: lupus, insulin dependent diabetes,multiple sclerosis |
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immunodeficiency diseases |
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Definition
lack components of immune system |
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hiv infects helper t ells that results in immune system attacking itself |
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endotherms derive heat from metabolism exoterms derive heat from environment |
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helps maintain balance of water and salt in blood and body fluids |
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