Term
What evidence is used to understand evolution? |
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Definition
Fossils
Embryology
Molecular - DNA and protein sequences
Compartive anatomy - homologous structures
(example of compartive anatomy) Vertebrae forearms |
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Term
Name the evidence of evolution:
bones used to look at previously living species |
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Definition
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Term
Name the evidence of evolution:
Looking at embryos to compare similar features |
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Definition
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Term
Name the evidence of evolution:
Looking at how DNA and proteins evolve over time and between species |
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Definition
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Term
Name the evidence of evolution:
comparing anatomy of living animals. Comparing features that evolved from a common ancestor and may have similar or different function in different species |
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Definition
Comparative anatomy - homologous structures |
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Term
Name the evidence of evolution:
Comparing anatomy of living animals. Structures that evolved seperately but perform similar function |
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Definition
Comparative anatomy - analogous structures |
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Term
Name the primate:
Larger than monkeys, bigger brains, lack tails
Ex humans and apes |
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Definition
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Term
Based on DNA evidence what is the closest living relative of humans? 98.8% genetically identical to us |
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Definition
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Term
What do we look at that tells us we 98.8% genetically similar to chimpanzee's? |
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Definition
Chromosome banding pattern |
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Term
Name the Ancient Hominid:
4.4 million years ago
Walked upright but not well
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Definition
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Term
Name the Ancient Hominid:
3.2 million years ago
True upright walking |
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Definition
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Term
Name the Ancient Hominid:
2.3 million years ago
First known tool user |
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Definition
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Term
Name the Ancient Hominid:
1.9 million years ago
Migrated out of Africa |
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Definition
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Term
Name the Ancient Hominid:
0.25 million years ago
From Europe and Asia. 99.7% identical to us |
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Definition
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Term
Name the Pre-Embryonic structure:
fertilized egg |
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Definition
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Term
Name the Pre-Embryonic structure:
Hollow ball with inner cell mass and trophoblast |
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Definition
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Term
Name the Pre-Embryonic structure:
Inside a blastocyst - embryonic stem cells will develop into embryo |
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Definition
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Term
Name the Pre-Embryonic structure:
Inside a blastocyst - outer sphere. will form embryonic part of placenta |
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Definition
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Term
Implantation: Blastocyst burrows into endometrium
Is this the 1st, 2nd, or 3rd step?
Trophoblasts secretes enzymes to create path |
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Definition
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Term
Implantation: Blastocyst burrows into endometrium
Is this the 1st, 2nd, or 3rd step?
Inner cell mass begins to develop into embryo |
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Definition
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Term
Implantation: Blastocyst burrows into endometrium
Is this the 1st, 2nd, or 3rd step?
Trophoblast begins to develop into placenta |
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Definition
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Term
Embryonic: Name the germ layer formed
Will form skin, nervous system |
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Definition
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Term
Embryonic: Name the germ layer formed
will for connective tissue, bone, muscle |
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Definition
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Term
Embryonic: Name the germ layer formed
will form lining of digestive tract, alveoli |
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Definition
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Term
Name the structure:
Interface between mother's and embryo's blood. Allow exchange of gases, nutrients, and waste |
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Definition
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Term
Name the embryonic structure:
Ectodermal fold on back of embryo will eventually form CNS |
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Definition
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Term
Name the embryonic structure:
mesodermal will form muscle and bone |
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Definition
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Term
Name the embryonic structure:
all 3 germ layers will form several face and neck parts |
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Definition
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Term
Name the embryonic stage:
all vertebraes look similar |
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Definition
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Term
Name the embryonic stage:
looks more human |
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Definition
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Term
Enzymes that cut DNA at specific sequences. Leaves overhangs of one strand. 2 different DNA molecules cut with the same enzyme can be combined |
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Definition
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Term
DNA cloning is done through the use of what structure? |
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Definition
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Term
Name the structure:
circular DNA molecule that is copied when inside growing bacteria |
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Definition
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Term
Name the step of DNA cloning:
1st, 2nd, or 3rd?
Cut gene out of DNA |
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Definition
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Term
Name the step of DNA cloning:
1st, 2nd, or 3rd?
Insert gene into plasmid |
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Definition
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Term
Name the step of DNA cloning:
1st, 2nd, or 3rd?
Put plasmid into bacteria and let bacteria make many copies |
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Definition
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Term
This process makes many copies of DNA, use DNA polymerase enzyme to copy DNA of interest |
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Definition
PCR (Polymerase chain reaction) |
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Term
PCR:
Short pieces of DNA bind to ends of target sequence. Show polymerase where to start |
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Definition
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Term
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Definition
Changing temperature several for 25-35 cycles |
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Term
Name the step of PCR:
1st, 2nd, or 3rd?
high temp causes DNA to unwind |
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Definition
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Term
Name the step of PCR:
1st, 2nd, or 3rd?
lower temp allows primers to bind to ends of target DNA sequence |
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Definition
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Term
Name the step of PCR:
1st, 2nd, or 3rd?
best temp for polymerase allows it to copy DNA |
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Definition
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Term
Method to seperate piece of DNA and visualize |
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Definition
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Term
Name the method of seperating DNA:
put DNA into gel and apply electric field
DNA moves towards + electrode
Smaller pieces move faster (seperate based on size)
Stain with dye that binds DNA and glows whne hit with UV light to see bands |
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Definition
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Term
The following are uses of what?
Make recombinant proteins - usually put gene into bacteria
Modify crops - agricultural uses
Modify animal - agricultural or research uses
Human gene therapy - correct a bad gene in pt. |
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Definition
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Term
Different forms of the same gene |
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Definition
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Term
Having 2 different alleles for a given gene, the gene is what? |
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Definition
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Term
Having 2 of the same alleles for a given gene, the gene is what? |
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Definition
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Term
What alleles you actually have
ex. Yy or yy |
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Definition
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Term
Observable result of allele
ex. yellow or green peas |
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Definition
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Term
Name the Mendel Law:
alleles for one gene seperate equally into gametes |
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Definition
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Term
Name the Mendel Law:
alleles for 2 different genes seperate independently (don't affect each other) |
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Definition
Law of independent assortment |
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Term
What is the exception to the law of independent assortment? (Mendel) |
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Definition
Genes that are close together on the SAME chromosome |
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Term
Failure of chromosomes to seperate correctly during meiosis |
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Definition
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Term
Name the cause of nondisjunction:
3 copies of a chromosome |
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Definition
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Term
Name the cause of nondisjunction:
1 copy of a chromosome |
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Definition
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Term
Most cases of this cause the embryo to die?
(failure of chromosomes to seperate correctly during meiosis) |
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Definition
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Term
The following are examples of what?
Down syndrome, monosomy X |
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Definition
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Term
How does cancer relate to the cell cycle? |
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Definition
Proteins controlling cell cycle are mutated |
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Term
Name the gene:
mutation makes them constantly push cell through cycle |
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Definition
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Term
Name the gene:
mutation causes loss of normal function to stop cell cycle |
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Definition
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Term
With the gradual accumulation of mutations, what happens? |
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Definition
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Term
Name the term related to cancer progression:
increased cell division |
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Definition
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Term
Name the term related to cancer progression:
change of cell morphology (shape) |
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Definition
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Term
Name the term related to cancer progression:
malignant, fast growing cells but staying in place |
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Definition
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Term
Name the term related to cancer progression:
cells spreading through tissue |
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Definition
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Term
Name the term related to cancer progression:
cells spreading to other organs |
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Definition
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Term
These can be chemicals, radiation, microorganisms |
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Definition
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Term
Name the term related to carcinogens:
cause the first mutation |
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Definition
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Term
Name the term related to carcinogens:
increases cell division and therefore, likelihood of further mutations |
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Definition
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Term
Complete carcinogens do what? |
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Definition
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Term
What are the defenses against cancer? |
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Definition
DNA repair, immune system, and cell death |
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Term
Name the defense against cancer:
needs to be done before the next round of DNA replication
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Definition
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Term
Name the defense against cancer:
cytotoxic T cells recognize different proteins and kill cancer cells |
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Definition
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Term
Name the defense against cancer:
cells have a suicide program-kill themselves if DNA too badly damaged |
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Definition
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Term
The following steps are involved with what?
Detach from tumor mass, move through tissue, cross capillary basement membrane, survive in blood, cross capillary basement membrane again, establish new tumor in different organ |
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Definition
metastasis - getting to another organ |
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Term
Cancer cells stimulate the growth of new blood vessels towards the tumor. Release chemical messengers that stimulate the vessels to grow |
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Definition
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Term
Name the type of cancer treatment:
A: This removes the tumor
D: does not remove metastatic tumor cells and may miss invasive cells in same organ |
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Definition
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Term
Name the type of cancer treatment:
A: drugs that target dividing cells; interfere with DNA synthesis
D: other dividing cells besides cancer - loss of hair, nausea/vomiting, anemia, infection |
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Definition
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Term
Name the type of cancer treatment:
A: stronger effect on dividing cells than non-dividing cells
D: only targets one area - wont affect metastatic tumor in different oragn damages DNA of some normal cells - causes mutations |
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Definition
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Term
Name the new cancer treatment:
stimulate pt. immune system to attack tumor
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Definition
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Term
Name the new cancer treatment:
drugs that block new blood vessel growth; starve tumor and decrease metastasis |
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Definition
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Term
Name the new cancer treatment:
drug that blocks metastasis |
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Definition
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Term
Name the new cancer treatment:
drugs that block activity of oncogene |
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Definition
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Term
Name the new cancer treatment:
give pt. an engineered virus that will infect and kill tumor cells only |
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Definition
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Term
Name phase of the cell cycle:
mitosis (nuclear division) and cytokinesis (cell division) occur |
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Definition
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Term
Name phase of the cell cycle:
cell growth, preparation of DNA synthesis |
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Definition
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Term
Name phase of the cell cycle:
DNA synthesis |
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Definition
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Term
Name phase of the cell cycle:
preparation for mitosis |
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Definition
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Term
Name phase of the cell cycle:
exit from cell cycle |
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Definition
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Term
What is the order of the cell cycle? |
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Definition
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Term
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Definition
Double helix unwinds, DNA polymerase adds new nulceotides one at a time. Nucleotides are complementary to parent strand |
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Term
DNA complementary nucleotides:
what pairs with A? |
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Definition
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Term
DNA complementary nucleotides:
What pairs with C? |
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Definition
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Term
Chromosomes are said to be _______ when cells have 2 copies of each chromosome (1 from mom and 1 from dad) |
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Definition
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Term
Both homologous chromosomes are copied in the S phase. These copies are called _____ ______ |
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Definition
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Term
Name the phase of mitosis:
chromosomes condense, spindle forms |
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Definition
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Term
Name the phase of mitosis:
chromosomes attach to spindle and line up at center of cell |
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Definition
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Term
Name the phase of mitosis:
sister chromatids seperate and move toward opposite sides of cell |
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Definition
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Term
Name the phase of mitosis:
chromosomes reach the end of spindle, chromosomes decondense, new nuclear envelopes form |
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Definition
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Term
Cleavage furrow forms and pinches off new daughter cells |
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Definition
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Term
Meiosis has how many divisions? |
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Definition
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Term
Name the division of meiosis:
1 or 2?
Homologous chromosomes line up side by side at metaphase crossing over exchanges DNA (mix up mom and dad's genes0 entire chromosome (with both sister chromatids) goes to daughter cells |
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Definition
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Term
Name the division of meiosis:
1 or 2?
works just like mitosis (sister chromatids seperate) result is 4 haploid cells (only one copy of each chromosome) each chromosome is mom's or dad's or a mixture |
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Definition
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Term
What is the result of meiosis? |
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Definition
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Term
What is the following process?
DNA unwinds at the gene to be expressed. RNA polymerase copies by adding nucleotides (AU, GC), splicing (introns removed) mRNA moves out of nucleus to cytoplasm |
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Definition
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Term
What is the following process?
ribosomes and tRNA read the genetic code. tRNA anticodon binds to mRNA codon. tRNA brings amino acid with it. ribosome holds everything in place and forms new peptide bond. starts at AUG codon and ends at stop codon |
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Definition
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Term
Name the type of mutation:
mutation that is passed to offspring |
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Definition
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Term
Name the type of mutation:
mutation not passed to offspring but can affect individual |
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Definition
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