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Final Exam: Section 5
Cerebral Cortex
51
Other
Undergraduate 3
12/15/2015

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Term
Spiny pyramidal neurons contain ______ & are excitatory
Definition
glutamate
Term
Spiny pyramidal neurons are _____ neurons & their major axons enter the white matter
Definition
projection neurons
Term
Cells in _____ layers tend to project to subcortical targets
Definition
deep
Term
Layer ____ cells tend to project to the thalamus, mainly to specific relay nuclei
Definition
6
Term
Layer _____ cells tend to project to non-thalamic structures
Definition
5
Term
Cells in ______ layers tend to project to other cortical areas
Definition
superficial
Term
Both layers 2 & 3 have ______ projections
Definition
associational
Term
Layer _____ is the primary source of callosal axons that travel to the opposite hemisphere
Definition
3
Term
Commissural projections are _____ if they innervate the same cytoarchitectonic division on the opposite side & ______ if they innervate a different cortical division
Definition
homotopic; heterotopic
Term
The _____ cell is the only known type of excitatory interneuron in the cortex
Definition
stellate
Term
Most local circuit neurons are inhibitory _____ cells with smooth, aspiny dendrites
Definition
GABA
Term
The ______ cell makes local connections & synapses onto the axon initial segment of pyramidal neurons
Definition
chandelier
Term
The _____ cell gives rise to vertically directed axons that target the distal dendrites of pyramidal cells & non-pyramidal cells across multiple layers
Definition
double bouquet
Term
Large _____ cells have axons that spread horizontally & synapse onto the soma & proximal dendrites of pyramidal neurons within the same layer
Definition
basket
Term
______ cells inhibit other pyramidal neurons, providing the necessary connections for feedback, feedforward, & lateral inhibition as well as more complex processing
Definition
basket
Term
_____ cells synapse onto the distal dendrites of both pyramidal neurons & other interneurons (the latter for potential disinhibition)
Definition
double bouquet
Term
Most ______ input to pyramidal cells terminate distally, while most _____ inputs terminate proximally
Definition
excitatory; inhibitory
Term
In sensory cortices, the major excitatory input is from _____
Definition
specific thalamic nuclei
Term
Specific thalamic nuclei terminate in layer _____ on stellate cells or pyramidal neurons, with additional sparse inputs to basket cells
Definition
4
Term
_______ afferents constitute the major excitatory input to association regions & synapse mainly onto pyramidal or stellate neurons
Definition
cortico-cortical
Term
_______ cortico-cortical afferents originate from layers 2/3 & terminate in layer 4
Definition
low to high/feedforward
Term
______ cortico-cortical afferents originate from layers 5/6 & terminate in layers 1 & 6
Definition
high to low/feedback
Term
______ afferents synapse primarily within layer 1 & innervate the distal dendrites of pyramidal cells
Definition
intralaminar thalamic
Term
Intralaminar thalamic inputs increase the overall _____ of cortical neurons to promote a conscious state that is able to process information
Definition
excitability
Term
The entire cortex receives modulatory inputs from _______ & ______ containing cells located in the reticular formation, basal forebrain, & hypothalamus
Definition
monoamine & peptide
Term
Cortical regulation of complex behaviors involves ______ of separate stimulus features through divergent pathways
Definition
parallel processing
Term
Cortical regulation of behavior involves ______ of increasingly complex stimulus features
Definition
serial processing
Term
The ______ is involved in decision making, executive functions, & future planning
Definition
prefrontal cortex
Term
The prefrontal cortex, limbic cortex, & parietal-temporal-occipital cortex make up the three major ______
Definition
multimodal association cortices
Term
The _______ occurs at the interface of higher order somatic, visual, & auditory regions
Definition
parietal-temporal-occipital association cortex
Term
_______ requires the convergence of visual & proprioceptive information
Definition
hand & eye coordination
Term
Damage to parietal-occipital association cortex gives rise to ______, difficulty in using visual guidance to perform motor tasks or to reach for & grasp objects
Definition
optic ataxia
Term
Damage to association cortex within the temporal lobe leads to ______
Definition
agnosias
Term
_______ is the inability to recognize objects by touch based on their texture, size, & weight
Definition
astereognosis
Term
______ is the inability to distinguish visual shapes
Definition
apperceptive agnosia
Term
Right parietal association damage leads to ______, a tendency to ignore sensory information from the opposite side of the body
Definition
neglect/hemi-neglect
Term
Neglect occurs in both the ______ & ______ domains
Definition
somatosensory & visual
Term
Neglect affects information that is called to mind from ______
Definition
memory
Term
Patients with hemi-neglect exhibit _______ (difficulty in copying or constructing figures)
Definition
constructional apraxia
Term
Cortical functions that are not conducted equally in both hemispheres exhibit _______
Definition
cerebral lateralization/hemispheric dominance
Term
______ is the tendency to develop fine motor control in only one hand
Definition
handedness
Term
Language is lateralized, being more developed in the _____ hemisphere
Definition
left
Term
Broca's area is important for the ______ of speech
Definition
generation
Term
Wernicke's area is important for the ______ of speech
Definition
comprehension
Term
In reading, written words are processed through visual cortices, then in ______ for comprehension
Definition
Wernicke's area
Term
In listening to spoken words, the auditory signals are processed through auditory cortices & then in ______ for comprehension
Definition
Wernicke's area
Term
Patients with damage to ______ have motor (expressive) aphasia
Definition
Broca's
Term
Patients with motor aphasia suffer impaired speech ability & experience ______, the inability to write
Definition
agraphia
Term
Patients with damage to ______ exhibit sensory (receptive) aphasia
Definition
Wernicke's area
Term
Patients with sensory aphasia exhibit ______, the inability to read
Definition
alexia
Term
Patients with damage to both Broca's & Wernicke's/medial temporal areas have _____
Definition
global aphasia
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