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First Aid Pharmacology
Antidotes, Drug Reactions, P450 interactions, Sulfa Drugs
110
Medical
Graduate
03/06/2013

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Cards

Term
Coronary vasospasm
Definition
Cocaine, sumatriptan, ergot alkaloids
Term
Cutaneous flushing
Definition
Vancomycin, adenosine, niacin, Ca2+ channel blockers

Mnemonic: VANC
Term
Dilated Cardiomyopathy
Definition
Doxorubicin, daunorubicin
Term
Tornadoes de pointes
Definition
Class III (sotalol) and class IA (quinidine) antiarrhythmics
Term
Agranulocytosis
Definition
Clozapine, carbamazepine, Colchicine, propylthiouracil, methimazole, dapsone

Mnemonic: Agranulocytosis could certainly cause pretty major damage.
Term
Aplastic anemia
Definition
Chloramphenicol, benzene, NSAIDS, Propylthiouracil,methimazole
Term
Direct Coombs positive hemolytic anemia
Definition
Methyldopa, penicillin
Term
Gray Baby Syndrome
Definition
Chloramhenicol
Term
Hemolysis in GP6D deficient patients
Definition
Isoniazid, sulfonamides, primaquine, aspirin, ibuprofen, nitrofurantoin

Hemolysis IS PAIN
Term
Megaloblastic anemia
Definition
Phenytoin, methotrexate, Sulfa Drugs

Have a blast with PMS
Term
Thrombotic complications
Definition
OCPs
Term
Cough
Definition
ACE inhibitors
Term
Pulmonary Fibrosis
Definition
Bleomycin, amiodarone, bulsulfan
Term
Acute cholestatic hepatitis, jaundice
Definition
Erythromycin
Term
Focal to massive hepatic necrosis
Definition
Halothane, Amanita phalloides, valproic acid, Acetaminophen

Mnemonic: liver "HAVAc"
Term
Hepatitis
Definition
INH
Term
Pseudomembranous colitis
Definition
Clindamycin, ampicillin
Term
Adrenocortical insufficiency
Definition
Glucocorticoid withdrawal
Term
Gynecomastia
Definition
Spironolactone, Digitalis, Cimetidine, Alcohol, Ketoconazole

Some Drugs Create Awkward Knockers
Term
Hot flashes
Definition
Tamoxifen, clomiphene
Term
Hyperglycemia
Definition
Niacin, tacrolimus, protease inhibitors, HCTZ, corticosteroids
Term
Fat redistribution
Definition
Glucocorticoids, protease inhibitors
Term
Gingival hyperplasia
Definition
Phenytoin, verapamil
Term
Myopathies
Definition
Fibrates, Niacin, Colchicine, Hydroxychloroquine, Interferon-alpha, Penacillamine, Statins, Glucocorticoids

Fish N CHIPS Give you Myopathies
Term
Gout
Definition
Furosemide, thiazides, niacin, cyclosporine
Term
Osteoporosis
Definition
Corticosteroids, heparin
Term
Photosensitivity
Definition
Sulfonamides, Amiodarone, Tetracycline

SAT for a Photo
Term
Rash (SJS)
Definition
Penicillin, Ethosuxamide, Carbamazepine, Sulfa drugs, Lamotrigine, Allopurinol, Phenytoin, Phenobarbital

Bad rash after a PEC SLAPP
Term
SLE-like syndrome
Definition
Hydralazine, INH, Procainamide, Phenytoin

It's not HIPP to have lupus
Term
Teeth (kids)
Definition
Tetracyclines
Term
Tendinitis, tendon rupture, and cartilage rupture
Definition
Fluoroquinolones
Term
Diabetes insipidus
Definition
Lithium, demeclocycline
Term
Fanconi's syndrome
Definition
Expired tetracycline
Term
Hemorrhagic cystitis
Definition
Cyclophosphamide, isofosphamide
Term
SIADH
Definition
Carbamazepine, cyclophosphamide
Term
Cinchonism
Definition
Quinidine, quinine
Term
Parkinson- like symptoms
Definition
Antipsychotics, reserpine, metoclopramide
Term
Seizures
Definition
Isoniazid, Bupropion, Imipenem/cilastatin, Tramadol, Enflurane, Metoclooramide

With seizures, I BITE My tongue
Term
Tardiness dyskinesia
Definition
Antipsychotics
Term
Antimuscarinic
Definition
Atropine, TCAs, H1-blockers, neuroleptics
Term
Disulfiram-like reaction
Definition
Metronidazole, certain cephalosporins, pricarbazine, 1st generation sulfonylureas
Term
Nephrotoxicity/ototoxicity
Definition
Aminoglycosides, vancomycin, loop diuretics, cisplatin
Term
Hypothyroidism
Definition
Lithium, Amiodarone, Sulfonamides
Term
Interstitial nephritis
Definition
Methicillin, NSAIDs, furosemide
Term
Acetaminophen
Definition
N-acetylcysteine (replenishes glutathione)
Term
Salicylates
Definition
NaHCO3 (alkanalize urine), dialysis
Term
Amphetamines (basic)
Definition
NH4Cl (acidify urine)
Term
Acethylcholinesterase inhibitors, organophosphates
Definition
Atropine, pralidoxime
Term
Antimuscarinic, anticholinergic agents
Definition
Physostigmine salicylate, control hyperthermia
Term
Beta blockers
Definition
Glucagon
Term
Digitalis
Definition
Normalize K, Lidocaine, Anti-dig Fab fragments, Mg2+ (KLAM)
Term
Iron
Definition
Deferoxamine, deferasirox
Term
Lead
Definition
CaEDTA, dimercaprol, succimer, penicillamine
Term
Mercury, arsenic, gold
Definition
Dimercaprol (BAL), succimer
Term
Copper, arsenic, gold
Definition
Penicillamine
Term
Cyanide
Definition
Nitrite+thiosulfate, hydroxocobalamin
Term
Methemoglobin
Definition
Methylene blue, vitamin C
Term
Carbon monoxide
Definition
100 oxygen, hyperbaric oxygen
Term
Methanol, ethylene glycol (antifreeze)
Definition
Fomepizole > ethanol, dialysis
Term
Opioids
Definition
Naloxone/Naltrexone
Term
Benzodiazepines
Definition
Flumazenil
Term
TCAs
Definition
NaHCO3 (plasma alkalinization)
Term
Heparin
Definition
Protamine
Term
Warfarin, rodenticides
Definition
Viamin K, fresh frozen plasma
Term
tPA, streptokinase, urokinase
Definition
Aminocaproic acid
Term
Theophylline
Definition
Beta-blocker
Term
Serotonin
Definition
Cyproheptadine (antihistamine with antiserotonergic properties)
Term
Methotrexate
Definition
Leucovorin (folinic acid)
Term
Cyclophosphamide, Isophosphamide
Definition
Mesna
Term
Chemo induced vomiting
Definition
Odansetron (5HT3 inhibitor)
Term
Chemo induced neutropenia
Definition
Filgrastin
Term
Doxorubicin
Definition
Dexrazoxone
Term
Platinum containing/ alkylating chemotherapeutic agents (cisplatin)
Definition
Amifostine (cytoprotective free radical scavenger)
Term
-azole
Definition
antifungal

eg Ketoconazole
Term
-cillin
Definition
Penicillin

eg Methicillin
Term
-cycline
Definition
Antibiotic, protein synthesis inhibitor

eg Tetracycline
Term
-navir
Definition
Protease Inhibitor

eg Saquinavir
Term
-triptan
Definition
5-HT (1b/1d) agonist (migraine)

eg Sumatriptan
Term
-ane
Definition
Inhalational general anesthetic

eg. Halothane
Term
-caine
Definition
Local anesthetic

eg. Lidocaine
Term
-operidol
Definition
Butyrophenon (neuroleptic)

eg. Haloperidol
Term
-azine
Definition
Phenothiazine (neuroleptic, antiemetic)

eg. Chlorpromazine
Term
-barbital
Definition
Barbiturate

eg. Phenobarbital
Term
-zolam
Definition
Benzodiazepine

eg. Alprazolam
Term
-azepam
Definition
Benzodiazepine

eg. Diazepam
Term
-etine
Definition
SSRI

eg. Fluoxetine
Term
-ipramine
Definition
TCA

eg. Imipramine
Term
-triptyline
Definition
TCA

eg. Amitriptyline
Term
-olol
Definition
beta-antagonist

eg. Propranolol
Term
-terol
Definition
beta2-antagonist

eg. Albuterol
Term
-zosin
Definition
alpha-1 antagonist

eg. Prazosin
Term
-oxin
Definition
Cardiac glycoside (inotropic agent)

eg. Digoxin
Term
-pril
Definition
ACE inhibitor

eg. Captopril
Term
-afil
Definition
Erectile dysfunction

eg. Sildenafil
Term
-tropin
Definition
Pituitary hormone

eg. Somatotropin
Term
-tidine
Definition
H2 antagonist

eg. Cimetidine
Term
-bendazole
Definition
Benzimidazole

eg. mebendazole
Term
-chol
Definition
Muscarinic agonist

eg. Bethanechol
Term
-curium
Definition
Non-depolarizing neuromuscular blocker

eg. Atracurium
Term
-curonium
Definition
Non-depolarizing neuromuscular blocker

eg. Vecuronium
Term
-dipine
Definition
Dihydropyridine calcium channel-blocker

eg. Nifedipine, Amlodipine
Term
-dronate
Definition
Bisphosphonate

eg. Aledronate, Olendronate
Term
-glitazone
Definition
Thiazolidinedione

eg. Pioglitazone, Rosiglitazone
Term
-mab
Definition
Monoclonal antibody

eg. Infliximab
Term
-mustine
Definition
Nitrosurea (nitrogen mustard)

eg. Lomustine
Term
-phylline
Definition
Methylxanthine

eg. Theophylline
Term
-prost
Definition
Prostaglandin analog

eg. Latanoprost
Term
-sartan
Definition
Angiotensin receptor blocker

eg. Losartan
Term
-statin
Definition
HMG-CoA reductase inhibitor

eg. Atorvastatin
Term
-stigmine
Definition
Anticholinesterase

eg. neostigmine
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