Term
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Definition
Binds membrane ergosterol and punctures membrane
used topically or iv for serious systemic micosis
RENAL TOXIC |
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Term
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Definition
Binds membrane ergosterol
used topical only
RENAL toxic, diaper rash, oral candidiasis |
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Term
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Definition
inhibits ergosterol synthesis
topical...system replaced by fluconzole |
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Term
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Definition
inhibits ergosterol synthesis
DRUG CHOICE CANDIDOSIS...inhibits cyps therefore interact many drugs
CRYPTOCOCCAL MENINGITIS AIDS and candidal infections all types |
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Term
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Definition
inhibits squalene epoxidase in ergosterol synthesis
ACCUMULATES IN NAILS |
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Term
|
Definition
inhibits thymidylate synthase
CNS
usually used with AMPHOB |
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Term
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Definition
disrupts mitotic spindle
specific for MICROSPORUM,EPIDERMOPHYON,TRICHOPHYTON
and DERMATOPHYTE |
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Term
|
Definition
disrupts cell wall
inject iv. used for azole resistant bacteria and INVASIVE ASPERGILLIS |
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