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Gastrointestinal Tract
N/A
95
Biology
Undergraduate 1
10/14/2012

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Term
What are the three layers of the Gastrointestinal Tract?
Definition
  1. Adventitia (Serosa)
  2. Muscularis externa
  3. Submucosa
  4. Mucosa
Term
What are Outgrowths on the GI tract called?
Definition
Accessory Organs
Term
What are Five examples of the Accessory Organs found off the GI tract?
Definition
  • Gall Bladder
  • Appendix
  • Pancreas
  • Liver
  • Salivary Glands
Term
What is Peristalsis?
Definition
Propulsion of a food bolus through the GI tract
Term
Where does Peristalsis occur?
Definition
Oesophagus, Stomach, Small and Large Intestine
Term
What are the Four divisions of the stomach?
Definition
Cardia, Fundus, Body, Pylorus
Term
What are Rugae?
Definition
Folds of the Mucosa and Submucosa which allow for the expansion of the stomach
Term
What are the three properties of Chief Cells?
Definition
Secrete enzymes, Lots of RER, Zymogen granules
Term
What are three properties of Parietal Cells?
Definition
Secrete HCl, Lots of Mitochondria, Microvilli (inserted or outside cells)
Term
How many layers of muscle does the Stomach have?
Definition
Three
Term
What layer of the mascularis is unique to the stomach?
Definition
The Oblique layer
Term
What is the name of the Sphincter at the base of the stomach, and what layer of muscularis creates it?
Definition
Pyloric Sphincter, Circular muscle layer
Term
Where does the head of the pancreas lie?
Definition
In the 'C' of the duodenum
Term
Where does the tail of the Pancreas reach?
Definition
The Spleen
Term
What is the Hepatopancreatic Ampulla?
Definition
The point where both the pancreatic and common bile ducts meet
Term
What is the Greater Duodenal Papilla?
Definition
Where the heptopancreatic duct enters into the duodenum
Term
What does the Sphincter of Oddi control?
Definition
The release of substances out of the greater duodenal papilla
Term
What is Chyme?
Definition
A mixture of acid and digested food found in the stomach which moves into the duodenum
Term
How is the pH of the chyme controlled?
Definition
The secretion of pancreatic bicarbonate
Term
What are the leaf-like surface projections on the wall of the small intestine called?
Definition
Plicae Cirulares
Term
What intestinal wall layer is the Plicae Circulares made from?
Definition
Submucosa
Term
What are the Villi extensions of?
Definition
Lamina Propria
Term
What is the Crypt of Lieberkuhn?
Definition
A gland between Villi which secretes various enzymes
Term
Villi have blood vessels and lymphatic vessels running through them, true or false?
Definition
True
Term
What is the the name of the lymphatic duct that runs through a vili?
Definition
Lacteal
Term
What are Paneth cells in regards to the small intestinal epithelium?
Definition
Cells which perform secretions
Term
Do microvilli have a glycoprotein coat?
Definition
Oui oui garson
Term
What is the "Brush border"?
Definition
A epithelial surface covered with microvilli, enzymes may attach here
Term
What is the order of structures of the Large Intestine?
Definition
Ascending colon --> Hepatic flexure --> Transverse colon --> Splenic flexure --> Descending colon --> Sigmoid colon --> Rectum --> Anal canal
Term
What are Haustra?
Definition
Small pouches on the small intestine?
Term
What is a Epipoic appendage?
Definition
A fatty outgrowth on the large intestine
Term
What is the Ileocecal Valve?
Definition
A sphincter that separates the Ilium from the Cecum
Term
How many anal sphincter are there?
Definition
Two
Term
The internal sphincter is smooth/skeletal muscle and has voluntary/involuntray control of bowel movements. It is innervated by parasympathetic/sympathetic nerves.
Definition
Smooth, Involuntary, Parasympathetic
Term
What needs to occur to the internal and external sphincters in order for defication to occur?
Definition
They must relax
Term
What is the haemorrhoidal plexus?
Definition
Veins in the rectum that are very close to the epithelial membrane
Term
How do Haemroids occur?
Definition
The enlargement of the haemorrhoidal plexus due to too much force being used
Term
What does the function of the fasting motility pattern achieve?
Definition
"House keeping"
Term
How long after a meal does the fasting motility pattern occur?
Definition
4-5 hours
Term
What are the three 2 hour cycles that occur in the fasting motility pattern?
Definition
  1. Inactivity
  2. Intermittent activity
  3. Intense activity
Term
What dictate the Basic Electrical Rhythm (BER) strength?
Definition
Frequency of the rhythm, Nerves and Hormones (strength)
Term
What are the three stages of feeding motility?
Definition
  1. Storage
  2. Peristalsis
  3. Segmentation
Term
How is storage achieved in the stomach and if the volume of the stomach increases, what happens to the pressure?
Definition

Rugae, Relaxation of smooth muscle

 

Pressure stays the same

Term
What does Segmentation occur?
Definition
Mixing substances and increasing exposure to absorptive surfaces
Term
What has reflex control when chewing?
Definition
Strength, Frequency, Side of chewing
Term
What are Three functions of Chewing?
Definition
Reduction of food particle size, Tasting, Mixing of food with saliva
Term
What is the difference in the two patterns of peristalsis that occur in the stomach?
Definition
The first hour is gentle while hours 1-5 are intense
Term
What are two functions of the Large Intestine? 
Definition
Storage of faeces and the regulation of water and salt in faeces
Term
Does Segmentation occur in the Large Intestine?
Definition
Yes
Term
What is a regular amount of mass movements in the large intestine per day?
Definition
3-4
Term

What are the amounts of secretione that occur in:

Salivary Glands

Gastric Glands

Pancreatic Secretions

Small intestine

Definition

1.5 L

2-4 L

0.5 L

1.5 L

Term
What type of cells does serous secretion come from in the saliva?
Definition
Acinar cells
Term
What does the Sublingual gland secrete?
Definition
Mucous and Lipase
Term
What two ways is salivary secretion regulated?
Definition

Conscious nervous input

Unconscious nervous input

Term
What four components make up gastric secretion?
Definition
HCl, Mucus, Pepsinogen, Intrinsic factor
Term
What does Instrinsic Factor do?
Definition
Aids with the absorption of Vitamin B12 in the small intestine
Term
How is Pepsinogen activated?
Definition
Autolytic cleavage and Acid in the gastric secretions
Term
How is acid secreted from Parietal cells?
Definition
By the use of the H+ - K+ pump
Term
Explain how the H+ - K+ pump in parietal cells works.
Definition
K+ on the outside of a cell is pumped into a cell while H+ is pumped out of a cell. An ATP is used in this process 
Term
What are the three phases of Gastric Secretion?
Definition
  1. Cephalic
  2. Gastric
  3. Intestinal
Term
What is the Entric Nervous System?
Definition
A localised nervous system to the GI tract
Term
During the Cephalic phase, what does the Enteric nervous system stimulate?
Definition
Parietal cell secretion and gastrin production
Term
What do GIP, CCK and Secretin do?
Definition
Inhibit Gastric secretions
Term
What are the two main components of pancreatic secretions?
Definition
Enzymes, Alkaline fluids
Term
Where is Bicarbonate produced in the pancreas?
Definition
In ducts
Term
What is the Vagovagal Gasastropancreatic reflex?
Definition
Stimulates pancreatic secretion
Term
Where is bile stored?
Definition
The Gall Bladder
Term
What does CCK do?
Definition
Stimulates the release of bile from the gall bladder
Term
What cells are enzymes attached to that help with contact digestion?
Definition
Enterocytes
Term
What carbohydrate cannot be digested by humans?
Definition
Cellulose
Term
How many amino acids are essential from the diet?
Definition
10 amino acids
Term
What are the enzymes involved in the breakdown of proteins?
Definition
Typsin and Chymotripsin --> Polypeptides and Proteases
Term
What are the Four stages of Lipid digestion?
Definition
Emulsification, Stabilisation, Digestion, Formation of micelles
Term
Describe the Emulsification stage of lipid digestion
Definition
Motility breaks the droplets into smaller droplets, increasing surface area
Term
Explain the digestion stage of lipid digestion
Definition
Involves lipase and a cofactor secreted by the pancreas. This converts triglycerides to monoglycerides and free fatty acids
Term
What substances are absorbed in the Mouth?
Definition
Lipid soluble substances
Term
What are four factors that would affect absorption?
Definition
Motility, Surface area, Passage across available surface and removal of substance from the interstitial space
Term
What are the two pathways that substances may be absorbed across an epithelium?
Definition
Paracellular and Cellular
Term
How do molecules pass through the Paracellular pathway?
Definition
Molecules pass through tight junctions between cells with a concentration gradient
Term

Is water absorption active or passive?

Explain how it occurs

Definition
Passive, an osmotic gradient is set up by the conentrations of salts and other nutrients
Term
Describe the four ways Na+ are transported
Definition
  1. Paracellular
  2. Na+ alone
  3. Na+ coupled to glucose
  4. Na+ couple to amino acids
Term
What does the SGLT-1 coupled transporter and is it Symport or Antiport?
Definition
It transports glucose from the intestinal lumen into the epithelium. It is an example of Symport transport
Term
How are lipids transported into the cell?
Definition
These are delivered to the brush border in micelles where they diffuse across the membrane into the cell
Term
How are transported out of the cells and where are they initially transported to?
Definition
As TAGs in chylomicrons, they are initially transported to the lacteals
Term
What mineral up-regulates the absorption of Calcium?
Definition
Vitamin D
Term
What is the mineral that enhances iron absorption?
Definition
Vitamin C
Term
What is the Mesentery?
Definition
A double layer of peritoneal membrane which attaches the body wall to organs
Term
What is the Omentum?
Definition
A double layer of peritoneal membrane which attaches organs to other organs
Term
The Celiac trunk supplies which region of the GI tract, Foregut, Midguy or Hindgut?
Definition
Foregut
Term
The Superior Mesenteric artery supplies which region of the GI tract, Foregut, Midgut or Hindgut?
Definition
Midgut
Term
The Celiac trunk supplies which region of the GI tract, Foregut, Midgut or Hindgut?
Definition
Hindgut
Term
What constitutes Foregut?
Definition
Stomach, duodenum, liver, gall bladder, spleen
Term
What constitutes the Midgut?
Definition
Small and large intestines
Term
What constitutes the Hindgut?
Definition
Large intestine and rectum
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