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Gen Physio- Urinary System
N/A
32
Other
Graduate
01/22/2012

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Cards

Term
What are the four purposes of the kidney?
Definition
produce urine, regulate fluid balance, regulate acid/base balance, endocrine
Term
Where is renin released?
Definition
wall of afferent arteriole
Term
where is blood pressure sensed
Definition
afferent arteriole
Term
does aldosterone directly affect urine accumulation
Definition
no
Term
where is aldosterone released from
Definition
adrenal cortex
Term
where is ACE found
Definition
the lungs
Term
what is in urine?
Definition
water, electrolytes, metabolic waste products, drugs and drug metabolites
Term
how many liters of blood do kidneys filter per day
Definition
1700
Term
what is considered the normal GFR
Definition
125 mL/min
Term
how can we measure GFR
Definition
creatinine clearance
Term
what is considered normal urine production
Definition
1 L/day
Term
what is in the renal plexus
Definition
sympathetic fibers and parasympathetic from vagus
Term
where is the urinary system located
Definition
abdomino-pelvic cavity
- retroperitoneal
Term
Where does blood from the kidney drain to
Definition
inferior vena cava
Term
how much of the blood do kidneys receive
Definition
20-25%
Term
is the blood supply of the kidney considered a portal system
Definition
no
Term
would i rather be a positive, negative or neutral molecule to filter through in the kidney
Definition
positive
Term
what are the main factors determining the pressure gradient
Definition
systolic BP, resistance of the glomerular capillary
Term
what causes relaxation of mesangial cells
Definition
ANP, dopamine, PGE2, cAMp
Term
what molecules make up the glomerular filter
Definition
podocalyxin and nephrin
Term
If I have too little Na, what happens
Definition
macula densa cells indirectly cause renin release and increased GFR
Term
What differs the PCT from DCT histologically
Definition
brush border of microvilli
Term
what ion is the greatest contributor to osmolality of ECF
Definition
sodium
Term
what is the threshold for glucose reabsorption
Definition
200 mg/dL
Term
what is only absorbed in the PCT
Definition
uric acid, glucose
Term
what is Bartter's syndrome
Definition
sodium chronically lost in urine, hypovolemia even if renin and aldosterone are released
Term
what increases sodium reabsorption
Definition
renin, angiotensin, aldosterone, norepinepherine, AVP
Term
is the thick or thin ascending loop more permeable to NaCL
Definition
thin
Term
what is the minimum and maximum excretion of urine per day?
Definition
0.5 L, 30 L
Term
What is the tightest type of epithelium in the body
Definition
transitional epithelium
Term
what hormone is responsible for determining the final concentration of urine
Definition
ADH
Term
How does ADH work
Definition
places aquaporins into tubule cells
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