Term
| List the 7 classical endocrine glands. |
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Definition
-Pituitary
-Thyroid
-Parathyroid
-Adrenal
-Pancreatic islets
-Gonads
-Placenta |
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Term
| T/F. Degradation plays a large role in fluctuating hormone levels. |
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Definition
| False. Hormones are typically degraded at steady rates so fluctuations are not a result of degradation. |
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Term
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Definition
| Metabolic clearance rate is the volume of plasma cleared of a hormone per unit of time (mls/min) |
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Term
| What are the three patterns of hormone secretion? |
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Definition
-cycles that are repeated in regular intervals
-pulsatile
-episodic |
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Term
| What functions as the biological clock to impose circadian rhythms? |
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Definition
| The suprachiasmatic nucleus (SCN) of the hypothalamus. |
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Term
| Where does the SCN send projections to? What are these areas involved in? |
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Definition
| -SCN sends projections to the subparaventricular zone and dorsomedial nucleus of the hypothalamus. These areas are involved in control of circadian rhythms. |
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Term
| Where does the SCN send inhibitory fibers? What does it control? |
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Definition
| The SCN also sends inhibitory neurons to the paraventricular nucleus (PVN) which controls sympathetic output to the pineal gland. |
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Term
| What produces melatonin? What regulates the production of melatonin? |
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Definition
| The pineal gland produces melatonin but the SCN regulates the production. |
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Term
| What are the requirements for a competitive binding assay? |
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Definition
-labeled hormone
-purified sample of the hormone with which to create a standard curve
-an antibody with a high specificity for that hormone
-means to separate the bound and unbound hormone
-samples of body fluid. |
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