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Genetics 3200 Lecture Exam 3
.
92
Biology
Undergraduate 4
10/19/2011

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Term
Adaptation hypothesis
Definition
a bacteria that has developed certain characteristics that allow them to surive in harsh environments
Term
Spontaneous Mutation
Definition
gain of new genetic abilities
Term
Lac+
Definition
can use lactose
Term
Lac-
Definition
cannot use Lactose
Term
minimal medium
Definition
starving bacteria & give them only bare necessities to see if they can survive
Term
Prototroph
Definition
can live in minimum medium
Term
Auxotroph
Definition
cannot live in minimum medium
Term
genetic recombination
Definition
replacement of one or more bacterail genes from a genetically distinct strand
Term
Rec A Protein
Definition
promote a genetic exchange between a DNA fragment & a donor
Term
Single Strand Displacement
Definition
takes in dsDNA and degrades one strang to use the other as a template
Term
Rec BCD proteins
Definition
untangle/ straighten
Term
Parasexual Process
Definition
ways that genetic recombination can take place
Term
conjugation
Definition
formation of sex pilus allowing to share genetic information
Term
transformation
Definition
picking up left behind DNA
Term
Transduction
Definition
gaining of genetic information
Term
bacterail conjugation
Definition
sharing of genetic info unidirectionally
Term
unidirectional transfer
Definition
single direction transfer
Term
episome
Definition
a plasmid that can replicate on its own
Term
episome
Definition
a plasmid that can replicate on its own
Term
autonomous state
Definition
can exist by itself
Term
integrated state
Definition
apart of the bacterial genome
Term
Hfr Cell
Definition
part of the genome
high frequency recombination cell
Term
donor bacteria
Definition
F+cell
Term
f-factor
Definition
fertility factor
owned by donor bacteria
Term
F-cell
Definition
recipient bacteria
Term
F pilus (sex pilus) is made from
Definition
f-factor cells
Term
conjugated channel
Definition
place where genetic exchange takes place
Term
internal sex filter
Definition
prevents cytoplasm from interfearing with the donor
Term
OriT
Definition
origin of transfer-- where DNA replication of the episome is initiated
Term
DNA relaxase
Definition
cleaves to the OriT site
Term
NICK
Definition
cuts the parallel and antiparallel strand
Term
OriV
Definition
initiation site of replication of the episome in bianary fision
Term
Oris
Definition
IF OriV is not working---initiation site of replication of the episome in bianary fision
Term
R Plasmid
Definition
a transferrable plasmid but cannot form a sex pilus or conjugational channel
Term
R-Determinants
Definition
R-Plasmid part that encodes genetic info about antibiotic resistance
Term
e transfer factor
Definition
helps the donor bacteria
Term
col plasmid
Definition
can be possessed by R Plasmid
encodes toxin protein
Term
competent bacteria
Definition
capable of being transferred
Term
DNA Translocase
Definition
brings DNA into cell
Term
Rec A Protein
Definition
incorporated DNA into bacterial genome
Term
Electroporation
Definition
expose bacteria to voltage to make membrane more permeable
Term
Lytic Phase
Definition
turns host cell into virus making factory
Term
steps to viral infection (5)
Definition
attachment- penetration-insertion-maturation-release
Term
ways a virus can penetrate (3)
Definition
fusion- channel formation- endocytosis
Term
Specialized Transduction
Definition
a genetic mistake when a small piece of bacterial DNA is packed into a virus
Term
generalized transduction
Definition
virus packs as muct host DNA into capsid as possible
Term
EHEC
Definition
complete transduction causing electrohemorrhighc disease
Term
hemmorhagic colitis
Definition
bleeding intestine
Term
hemolytic-uremic syndrome
Definition
type of EHEC
Term
Two purposes "b toxin" serves
Definition
cellular recognition biinding protein- activate "a toxins"
Term
globtriaosylceramide (Gb3)
Definition
glycolipid cell membrane receptor targeted by "b toxin"
Term
once in the nuclear envelope "a toxin" acts as
Definition
N-glycosidase
Term
chemokine interleukin 8
Definition
ligand that triggers chemotaxis
Term
chemotaxis
Definition
causes WBC to move to infection location
Term
microangiopathic hemolytic anemia
Definition
RBC in pieces
Term
thrombocytopenia
Definition
decrease in blood platelets
Term
Oliguria
Definition
low output of urine
Term
hematuria
Definition
RBC in urine
Term
staphloxathin
Definition
protective pigment of staphylococcus aureus
Term
reactive-oxygen intermediate (RIO)
Definition
oxygen free radical
Term
reactive-oxygen intermediate (RIO)
Definition
oxygen free radical
Term
reactive-oxygen intermediate (RIO)
Definition
oxygen free radical
Term
reactive-oxygen intermediate (RIO)
Definition
oxygen free radical
Term
phagosome
Definition
macrophage inside vesicle
Term
respiratory bursts initiates
Definition
membrane bounded oxidase
Term
membrane bounded oxidate causes oxygen reduction into (3)
Definition
02-
0H-
H2O2
Term
MRSA breaks
Definition
beta lactam
Term
function of beta lactam
Definition
prevent bacteria from forming a cell wall
Term
lacY gene
Definition
codes for beta glactoside permease
Term
lacZ gene
Definition
codes for enzyme beta galactosidase
Term
repression
Definition
gene off
Term
derepression
Definition
gene on
Term
biosynthetic pathway
Definition
amino acid synthesis
Term
regulator protein binding site (RPBS)
Definition
can turn off or on transcription of a gene. next to the promotor region of the gene that you are controlling
Term
effector molecules (2 groups)
Definition
inducer
co-repressor
Term
inducer
Definition
turns on gene expression
Term
co repressor
Definition
turns off gene transition
Term
allosteric transition
Definition
change in shape/function
Term
human growth hormone
Hgh
Definition
stimulates the rate of cell division/ cell growth
Term
stomatotrophin (aka)
Definition
Hgh
Term
stomatotrophic cells
Definition
produced in pituitary gland
Term
somatomedins
Definition
triggers skeletal muscles
insulin growth factor I & II
Term
Bacillus thurinigensis
Definition
produces naturally in insectiside called crystal toxin
Term
glycophosphate
Definition
round-up
herbicide
Term
Gros Michel
Definition
bananas
Term
black sigatoka
fusarium oxyporum
Definition
kill gros michel
Term
cavendish
Definition
bananas eaten today
Term
Ice structuring protein
Definition
reduces freezing point
Term
RNA triphosphotase
Definition
comes in and removes 1 phosphate
Term
RNA gyanyltransferase
Definition
transfers GMP to diphosphate end
Term
RNA methyltransferase
Definition
adds a methyl group to the cap called 7-methylguanosine
Term
nucleopores
Definition
channel protein on nuclear membrane
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