Term
| Brand name for omeprazole |
|
Definition
|
|
Term
| Brand name for Omeprazole - Na Bicarb |
|
Definition
|
|
Term
| Brand name for Pantoprazole |
|
Definition
|
|
Term
| Brand name for Lansoprazole |
|
Definition
| Prevacid, Prevacid SoluTab |
|
|
Term
| Brand name for Esomeprazole |
|
Definition
|
|
Term
| Brand name for Rabeprazole |
|
Definition
|
|
Term
|
Definition
PPIs are taken daily, before breakfast, to treat duodenal and gastric ulcers. If this fails, BID (2nd close before dinner) can be tried. Some are right before eating - others are 30 - 60 minutes before food.
|
|
|
Term
| Which PPIs are most effective? |
|
Definition
Alls imilarly effective - generic should be tried 1st |
|
|
Term
| Why is it good to limit PPI use? |
|
Definition
Increased risk of osteoporsos/fracture with long-term use-good reason to limit use |
|
|
Term
| What other precautions do PPI have? |
|
Definition
(A) Can increase INR if using warfarin (monitor)
(B) Can increase risk pneumonia in hospitalized patients
|
|
|
Term
|
Definition
| Statement. Not a question. |
|
|
Term
| PPIs should be used cauttiously with? |
|
Definition
Caution with concurrent use of itraconazole, ketoconazole, calcium carbonate and iron, due to reduced absorption from increased pH. |
|
|
Term
|
Definition
PPIs inhibit 2C19:...may prevent conversion of clopidogrel to the active form ---> pantoprazole may have lower DI risk. |
|
|
Term
|
Definition
Take before breakfast. If twice daily, take before breakfast and dinner.
|
|
|
Term
| If taking long-term ensure that calcium and vitamin D intake is optimal. Recommend ________. |
|
Definition
calckum citrate formulations (improved absorption in basic pH). |
|
|
Term
| How to stop PPI medication |
|
Definition
Should "taper" the dose to avoid "acid rebound." RpH should recommend decreased dose, then every other day, over at least a coouple of weeks.
|
|
|
Term
| Should PPIs be used for occasional mild stomach upset? |
|
Definition
Do not use for occasional mild stomach upset: this can be effectively treated with an antacid (such as calcium carbonate) or a stronger medication such as famotidine (generic of Pepcid) |
|
|
Term
| Effervescent and orally dissolving formulations contain...? |
|
Definition
| phenylalanine - do not use with PKU! |
|
|
Term
| While using PPI, how long to wait before contacting doctor? |
|
Definition
|
|
Term
| How to take Prevacid SoluTab? |
|
Definition
Do not swallow whole. Place on tongue and allow to dissolve (with or without water), then swallow. |
|
|
