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Geriatrics Module
quiz 2 medications
15
Other
Graduate
03/14/2012

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Term
Heparin
Definition
incr ATIII, indicated for DVT. Contraindicated in pts. with low weight, bleeding risks and heparin induced thrombocytopenia (HIT).
Term
Enoxaparin
Definition
INC ATIII, indicated for DVT. Low molecular weight heparin. Contraindicated in pts. with low weight or bleeding risks.
Term
Warfarin
Definition
blocks vit k dependent process (2, 7, 9, 10 and c & S). Anticoagulant contraindicated in bleeding conditions (factor V leiden, etc.)
Term
Digoxin
Definition
cardiac glycoside indicated in a fib with CHF. Contraindicated in v-fib, v-tach, and in hypokalemic patients.
Term
Aspirin
Definition
inhibits prostaglandin synthesis and platelets. Indicated in stroke and MI prevention. Contraindicated in patients at risk for a GI bleed.
Term
Clopidogrel
Definition
inhibit adp receptor on platelets preventing their coagulation. useful in anti-platelet therapy. Contraindicated in bleeding conditions assoc. with platelet dysfunction.
Term
Atorvastatin
Definition
Inhibit HMG-CoA Reductase. Indciated in dyslipidemia but contraindicated with hepatic pathology, myopathy, severe metabolic conditions, and/or severe endocrine conditions.
Term
Simvastatin
Definition
Inhibit HMG-CoA Reductase. Indciated in dyslipidemia but contraindicated with hepatic pathology, myopathy, severe metabolic conditions, and/or severe endocrine conditions.
Term
Pravastatin
Definition
Inhibit HMG-CoA Reductase. Indciated in dyslipidemia but contraindicated with hepatic pathology, myopathy, severe metabolic conditions, and/or severe endocrine conditions.
Term
Isosoribide Mononitrate
Definition
inc cGMP to relax smooth muscle of vasculature. Contraindicated in hypotensive patients.
Term
Amiodarone**
Definition
Class III (prolongs phase 3) antiarrhythmic. Does so mainly by blocking potassium channels in cardiac smooth muscle.
Term
Midodrine**
Definition
Alpha-1 agonist used to reduce orthostatic hypotension. Contraindicated in cardiac or renal disease, thyrotoxicosis, pheochromocytoma, hypertension, and diabetes melitus
Term
Fludrocortisone
Definition
Synthetic corticosteroid that has higher mineralocorticoid potency than glucocorticoid potency. Useful in condicions such as Addison's disease or in 21-hydroxylase deficiency (defective cortisol synthesis). Contraindicated with systemic fungal infections or with live/attenuated vaccines.
Term
Predinsone
Definition
Glucocorticoid prodrug that is converted to the active form (prednisolone) by the p450 system of the liver, therefore it is usually taken orally. Indicated in asthma, COPD, rheumatic disorders, adrenal insufficiency (usually due to 21-hydroxylase autoantibodies), hypercalcemia (due to cancer), thyroiditis, etc. Contraindicated with systemic fungal infections or with live/attenuated vaccines.
Term
Epoetin alfa
Definition
Erythropoietin (EPO) analog. Useful in treating anemia commonly associated with chronic renal failure and cancer chemotherapy. Contraindicated in uncontrolled hypertension, pure red cell aplasia, neonates, infants, pregnant women, and nursing women
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