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GI: Pancreatitis
GI: Pancreatitis
20
Anatomy
Graduate
01/24/2012

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Cards

Term
causes of acute pancreatitis:
Definition
BEHAVEID:
- Biliary obstruction
- ETOH
- Hypercalcemia
- Abdominal trauma/surgery
- Vascular
- ERCP
- Infection- viral
- Drugs- Thiazides, Furosemide, Corticosteroids, Sulfonamides, Estrogens, ACE-I, Opiates, Acetaminophen, Cisplatin, Erythromycin, Metformin
Term
Drugs that may cause acute pancreatitis:
Definition
- Thiazides
- Furosemide
- Corticosteroids
- Sulfonamides
- Estrogens
- ACE-I
- Opiates
- Acetaminophen
- Cisplatin
- Erythromycin
- Metformin
Term
Causes of chronic pancreatitis:
Definition
- Chronic alcoholism
- Biliary obstruction-ampula stenosis, tumor
- Hereditary
- Severe malnutrition
- Idiopathic
- Untreated hyperparathyroidism
- Autoimmune 5%
Term
Pneumonic for causes of Pancreatitis:
Definition
I GET SMASHED
- Idiopathic
- Gallstones
- Ethanol
- Traumas
- Steroids
- Mumps/Malignancy
- Autoimmune
- Scorpion bite
- Hypercalcemia, Hyperlipidemia
- ERCP
- Drugs
Term
Symptoms of acute pancreatitis:
Definition
TEACHFJGC
- abrupt, steady, severe epigastric abdominal pain, radiates to back, wose with walking and supine, better with sitting and leaning forward
- Hypoactive bowel sounds/ileus
- Tachycardia/shock
- Confusion
- Fever
- Jaundice
- Ascites
- Cullen's sign (around umbillicus)
- Grey Turner's sign- bluish flank
Term
symptoms of chronic pancreatitis:
Definition
- persistent or recurrent epigastric and left upper quadrant pain +/- radiation to the back
- Guarding
- Weight loss
- Bulky, foul smelling, greasy stools
- Epigastric mass 10%
- Jaundice 5-10%
Term
Lab findings of acute pancreatitis:
Definition
A Little Light Provides Great Guidance Helping Bob Cross Avenues.
- Amylase increased
- Lipase increase
- Leukocytosis (10-30K)
- Proteinuria
- Granular casts
- Glycosuria
- Hyperglycemia
- BUN increased
- Cr increased
- ALT increased, > 150 units/L= biliary
Term
Lab findings of Chronic Pancreatitis:
Definition
An Animal Glided Torwards I.
- Amylase may be normal
- Alk phosph and bilirubin may be increased
- Glycosuria +/-
- Triglycerides increased
- IgG4 increased
Term
best test for pancreatitis:
Definition
CT
Term
Ranson's Criteria for Pancreatitis:
Definition
At Admission: GA LAW
- Glucose > 200
- Age > 55 y/o
- LDH > 350
- AST > 250
- WBC > 16,000

At 48 hours: CHOBBS
- Calcium < 2.0 mmol/L or 8.0 mg/dL
- Hematocrit fall of > 10%
- Oxygen (hypoxemia) PO2 < 60
- BUN increased by 1.8 mmol/L or 5 mg/dL after IV fluid hydration
- Base deficit of > 4mEq/L
- Sequestration of fluids > 6L
Term
Pancreatic Cancer Symptoms:
Definition
- Jaundice
- Dull/vague abdominal pain
- Weight loss
- Anorexia/change in taste
- Nausea
Term
PE fndings of Pancreatic Cancer:
Definition
- Icterus
- Cachexia
- Temporal Wasting
- Ascites
- Peripheral lymphadenopathy
- Hepatomegaly
- Excoriations from scratching pruritic skin due to jaundice
Term
Pancreatic Cancer is associated with:
Definition
- Smoking
- Alcoholism
- Genetics 5-10%
- Gallstones
- Diabetes Mellitus
- Chronic Pancreatitis
- High fat diet
- Obesity early in life
- Occupational exposure: oil refining, paper manufacturing, chemical industry
Term
Labs to run for pancreatic cancer:
Definition
A Bubble Had Total Armor:
- Alkaline phosphate
- Bilirubin
- Hematocrit
- Total Protein
- Amylase
Term
Whipple Procedure:
Definition
- Only indicated in 10-20% of those with lesions less than 5 cm
- surgical resection of the distal antrum of the stomach, first two segments of the duodenum, head of the pancreas, common bile duct, and the gallbladder
Term
Chemo used for pancreatic cancer:
Definition
- Gemcitabine
- Flurouracil
- Leucovorin
Term
Stage IV pancreatic cancer has a __ __ average survival rate.
Definition
6 month
Term
Localized pancreatic cancer has a ___ 5 year survival rate.
Definition
21.5%
Term
Regional pancreatic cancer has a __% survival rate.
Definition
8.7%
Term
Metastatic Pancreat Cancer has a __% survival rate.
Definition
1.8%
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