Term
|
Definition
|
|
Term
1st line glaucoma treatment |
|
Definition
beta blockers, prostaglandin analogs, brimonidine, topical carbonic anhydrase inhibitors |
|
|
Term
2nd line glaucoma treatment |
|
Definition
pilocarpine, apraclonidine |
|
|
Term
3rd line glaucoma treatment |
|
Definition
carbachol, oral carbonic anhydrase inhibitors, echothiophate |
|
|
Term
|
Definition
betaxolol, carteolol, levobunolol, metipranolol, timolol |
|
|
Term
|
Definition
decrease production of aqueous humor |
|
|
Term
|
Definition
systemic absorption, pulmonary (asthma, COPD), CV (bradycardia, congestive heart failure), diabetes |
|
|
Term
Beta blockers systemic side effects |
|
Definition
bronchospasm, CHF, bradycardia, hypotension, depression, lethargy, sexual dysfunction, increased cholesterol and triglycerides, mask hypoglycemia symptoms and reduced glucose tolerance in pts with diabetes |
|
|
Term
Beta Blockers Ocular Side effects |
|
Definition
stinging, dry eyes, blepharitis |
|
|
Term
Beta Blockers (ocular) interactions |
|
Definition
oral beta blockers, calcium channel blockers, quinidine |
|
|
Term
Synthetic prostaglandin F2alpha analogue |
|
Definition
Latanoprost, Tafluprost, Travoprost |
|
|
Term
Synthetic prostamide analogue |
|
Definition
|
|
Term
|
Definition
|
|
Term
increased uveoscleral outflow; increased trabecular outflow |
|
Definition
|
|
Term
|
Definition
1st line; reduce IOP 25-35% |
|
|
Term
Prostaglandin Analogues Cautions |
|
Definition
hypersensitivity, macular edema, ocular inflammation, preganancy |
|
|
Term
ocular side effects (prostaglandin analogues) |
|
Definition
hyperemia, darkening pigment, eyelash lengthening/thickening |
|
|
Term
Bimatoprost (latisse, Allergan) Common ADRs |
|
Definition
Eye pruritus, conjunctival hyperemia, skin hyperpigmentation |
|
|
Term
Adrenergic Agonists- Selective |
|
Definition
|
|
Term
|
Definition
first line- reduces IOP 18-27% at peak and 10% at 8-12 hours |
|
|
Term
|
Definition
|
|
Term
Brimonidine Systemic side effects |
|
Definition
lethargy, dry mouth/nose, reduced blood pressure |
|
|
Term
Brimonidine Ocular side effects |
|
Definition
|
|
Term
Apraclonidine cautions/SE |
|
Definition
tachyphylaxis and ocular allergy |
|
|
Term
Carbonic anhydrase inhibitors |
|
Definition
Brinzolamide, Dorzolamide and Timiolol |
|
|
Term
Carbonic anhydrase inhibitors |
|
Definition
First line; reduce IOP 15-26% |
|
|
Term
carbonic anhydrase inhibitors cautions |
|
Definition
systemic effects, sulfonamide allergy |
|
|
Term
carbonic anhydrase inhibitors systemic side effects |
|
Definition
bitter taste, headache, nausea, fatigue |
|
|
Term
carbonic anhydrase inhibitors ocular side effects |
|
Definition
blurred vision, stinging, ocular allergic reactions |
|
|
Term
Cholinergic Agonists Direct Acting |
|
Definition
Carbachol and pilocarpine |
|
|
Term
increased trabecular outflow |
|
Definition
cholinergic agonists direct acting |
|
|
Term
|
Definition
second line- reduces IOP 20-30% |
|
|
Term
Cholinergic Agonists Direct Acting Cautions and systemic side effects |
|
Definition
Miosis; headache, salivation, diarrhea, sweating, flushing |
|
|
Term
Cholinergic Agonists Direct Acting Ocular side effects |
|
Definition
myopia, brow pain, accommodative spasm |
|
|
Term
Cholinesterase Inhibitors |
|
Definition
|
|
Term
increased trabecular outflow |
|
Definition
|
|
Term
|
Definition
systemic effects, uveal inflammation, cataracts |
|
|
Term
echothiophate systemic side effects |
|
Definition
n/v/d, cramps, sweating, salivation, urinary incontinence |
|
|
Term
echothiophate ocular side effects |
|
Definition
burning, tearing, myopia, cataracts, iris cysts, brow pain, lid muscle twitching, conjunctival and ciliary redness |
|
|
Term
|
Definition
5-fluorouracil, Mitomycin (mitosol) |
|
|
Term
primary open-angle glaucoma symptoms |
|
Definition
usually none, occasionally headache and tired eyes |
|
|
Term
|
Definition
ophthalmic corticosteroids, systemic corticosteroids, inhaled/intranasal corticosteroids, fenoldopam, ophthalmic anticholinergics |
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