Term
| What are some of the common features (3) of all plasma membrane receptors? |
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Definition
1) an extracellular domain that binds the chemical messenger
2) one or more membrane-spanning domains that are alpha-helices
3) an intracellular domain that initiates signal transduction |
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Term
| The pathways of signal transduction for plasma membrane receptors have two major types of effects on the cell |
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Definition
(a) rapid and immediate effects on cellular ion levels or activation/inhibition of enzymes and/or
(b) slower changes in the rate of gene expression for a speciļ¬c set of proteins. |
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Term
| Plasma membrane receptors are grouped into these categories: |
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Definition
1) ion channel receptors
2) receptors that are kinases or bind kinases
3) receptors that work through second messengers |
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Term
| How many membrane spanning alpha-helices do heptathelical receptors contain? |
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Definition
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Term
| These receptors work through second messengers, which are small nonprotein compounds, generated in the cell in response to the messenger binding to the receptor? |
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Definition
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Term
| These are present in low concentrations so their concentration and hence their message can be rapidly initiated and terminated. |
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Definition
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