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Helminthes-Cestodes
UA, parasites, cestodes
49
Other
Undergraduate 3
06/16/2012

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Cards

Term
Diphillobothrium latum
Definition
broadfish tapeworm
Term
taenia solium
Definition
pork tapeworm
Term
taenia sanginata
Definition
beef tapeworm
Term
hymenolepsis nana
Definition
dwarf/rat tapeworm
Term
hymenolepsis dimunita
Definition
dwarf/rat tapeworm
Term
dipylidium caninum
Definition
dog and cat tapeworm
Term

diphobothrium latum

taenia solitum

taenia sanginata

hymenolepsis nana

hymenolepsis dimunata

dipylidium caninum

 

These are what kind of cestodes?

Definition
intestinal cestodes
Term
echinococcus granulosus
Definition
dog/hydatid tapeworm
Term
echinococcus multiocularis
Definition
hydatid disease
Term

echinococcus granulosis

echinococcus multiocularis

 

these are what type of cestodes

Definition
tissue cestodes
Term
cestodes or tapeworms belong to the phylum...
Definition
platyhelminth
Term

-known as flatworms

-dorsoventrally flattened and have solid bodies with no body cavity

-internal orans are imbedded in special tissue

-there are no respiratory or blood vascular systems

-life cycle of these organisms are generally indirect. they require at least one intermediate host to support larval development

Definition
Cestodes
Term
Internal organs of cestodes are embedded in tissue called
Definition
parenchyma
Term
Cestodes have an _________ host in which larval form lives and a __________ host in which adult worms live
Definition
intermediate, definitive
Term

Adult worm cestodes are characterized by segmented body parts:

Head or attachement portion is called ______ and has attachment mechanisms such as ______, ________, grooves or _____________.

reproductive structures contain uteri and intestine.

Definition
scolex, hooks, suckers, cutting plates
Term
__________ of tapeworms is highly absorptive and even releases digestive enzymes at its surface from specialized microvilli called_______
Definition
tegument (external surface), microtriches
Term
Why must adult cestodes absorb nutrients through the tegument? where are waste products release?
Definition
B/c they have no mouth, digestive tract, or vascular system. Wast products are also excreted through the tegument
Term

-ribbon like and flattened in cross section like a tape measure

-adult worm may range from a few millimeters to 20m in length

-anterior end of adult is modified for attachment to intestinal wall of the definitive host

-Scolex is usually equipped with four cup shaped suckers and some species also have a crown of hooks on the scolex to aid in attachment

Definition
Characteristics of cestodes
Term
Adult cestodes live in ________________ of vertabrate definitive host, wheras larval stage inhabits ________ of intermediate host
Definition
intestinal tract, tissue
Term
Usually equipped with four cup shaped suckers and some species also have a crown of hooks on this to aid in attachment
Definition
scolex
Term
entire body of tapeworm is termed
Definition
strobila
Term
cestodes body consist of segments called
Definition
proglottids
Term
In cestodes, each tapeworm is __________
Definition
hermaphroditic
Term
Reproductive organs in each proglottid mature gradually so the proglottids towards the terminus...
Definition
have fully developed reproductive organs and the uterus is filled with fertilized eggs
Term
proglottids break off from the chain are expelled...
Definition
in the feces
Term

 -an embryo seen with tapeworm eggs

-bears 6 tiny hooklets that facilitate entry of the embryo into the intestinal mucosa of the intermediate host

 

Definition
oncosphere
Term
where does the embryo go after it hatches from the eggshell
Definition
migrates through the intestinal wall and goes to a specific tissue site
Term

-broad fish tapeworm

-largest tapeworm affecting man (10m or more)

-infection is obtained by eating raw fish

Definition
epidemiology of diphyllobothrium latum
Term
minimal infection is usually picked up when large segments of worm are passed in the stool
Definition
diphyllobothrium latum
Term

-unembryonated eggs passed in feces

-eggs embryonate in water

-coracidia hatch from eggs and are ingested by crustaceans

-procercoid larvae in body cavity of crustaceans

-crustacean ingested by fish, procecroid larvae develops into plerocercoid larva

-human ingests raw or undercooked fish

-adults in small intestine

-proglottids release immature eggs

Definition
diphyllobothrium latum
Term

-identification of UNembryonated operculated eggs having an ab-opercular knob

-eggs passed in stool

-eggs measure 58-76um by 40-51  um

-eggs are often confused with the eggs of paragonamus westermani

-identification of worm segments passed in stool

-the characteristic morphology of the proglottid is that it is wider than it is long

-identification of the worm scolex (2 grooves)

Definition
diphyllobothrium latum
Term

-cow is the intermediate host

-infection obtained from eating undercooked infected beef

Definition
taenia saginata
Term

-minimal except for mild GI disturbance

-sparganosis will occasionally occur when man is infected with the egg and larvae encyst in various tissues including brain, but this is rare

Definition
taenia saginata
Term

-identification of eggs measuring 31-43um with radial pattern on the egg wall

-identification of adult worm (up to 5m long)

-scolex has 4 suckers for attachment

-proglottids with 15-20 uterine branches are also diagnostic

Definition
taenia saginata
Term

-gets its name since the pig is the intermediate host

-man may be definitive host by eating infected pork with man being the host to adult worm

-man may be intermediate host by ingesting eggs and becoming the host to the larval stage of the parasite

 

Definition
taneia solium
Term

-minimal symptoms when man is the host to the adult worm which lives in the intestine

-cystercosis

-man ingest eggswhich produce larvae that migrate to various host tissues including the brain

-here they encyst and stimulate vigorous inflammatory response

-lesions eventually are fibrosed off and calcify

-patients have seizures and other CNS symptoms during the acute inflammation period and after lesions calcify

 

Definition
taenia solium
Term

-egss in stool have thick walls with radical striations

-adult wom parts are also diagnostic

-scolex characterized by crown of hooks and 4 suckers

-proglottids shed in stool that have 7-13 uterine branches

-adult worms reach up to 3m long

Definition
taenia solium
Term

-infection by ingestion of eggs or by igestionn of beetles with cystecerci

-worldwide problem

-most common tapeworm infection is seen in children

-infects rat and mice, rarely seen in humans

 

Definition
Hymenolepsis nana and hymnolepsis diminuta
Term
-infection well tolerated with very few symptoms
Definition
hymenolepsis nana and hymenolepsis diminuta
Term

-eggs in stool are thin shelled, have six hook oncosphere and polar filaments

-measures 30-47um and 60-79 um

-scolex has 4 suckers with hooklets- rarely see adult worm in stool

Definition
Hymenolepsis nana and hymenolepsis diminuta
Term

-infects children with close dog/cat contact

-gravid proglottids or membrane bound egg packs are the diagnostic forms

-each egg measures 25-40um and contain six hooked oncosphere

Definition
dipylidium caninum
Term

-very small tapeworm (3-5 segments)

-the dog is the primary host, humans are accidental hosts

-dogs shed infective cysts in stool

-sheep or other herbivores ingest the cysts which hatch and infect tissues

-infection in humans results from eating infected tissues or eggs

-echinococcus hatches in the bowel and then migrate from the intestine to seed more tissues where cysts form containing infective scolexes

Definition
echinococcus granulosus (hydatid cyst)
Term

-diagnosis generally made based on serology

-diagnosis may also be made on the identification of the short tapeworms in the hydatid sand or biopsy

Definition
echinococcus granulosus (hydatid cyst)
Term

-causes alveolar hydatid cyst disease

-most lethal form of helminthic diseases with radical surgery still being the only curative therapy

-most cases are diagnosed in rural residents suggesting direct or indirect contact with fecal material from foxes and dogs

 

Definition
echinococcus multilocularis
Term

-adult worm 1.2-3.7 m

-eggs similar to taenia species and very resistant to cold

-cyst composed of many irregular cavities with little or no fluid, rare or no free scolexes and often central necrosis and cavitation of the lesion

-definitive host tends to be dogs, foxes, and cats and wolves while the intermediate host have been identified as field mice, house mice, squirrels and shrews.

Definition
echinococcus multilocularis
Term

-found in tissues, liver being most common

-disease may resemble a slowly growing carcinoma and may present symptoms of intrahepatic hypertension

-there may be hepatosplenomegaly, splenomegaly, jaundice and ascites

Definition
echinococcus multilocularis
Term

diagnosis of alveolar hydatid cyst disease may be difficult unless there is a presumptive diagnosis made based on history

diagnosis can be missed on autopsy

serology can be helpful

PCR developed for specific m-RNA from fine needle bioposy

Definition
Echinococcus multilocularis
Term

-surgical removal of cyst is almost impossible due to no limiting capsule

-mebendozale is parisitostatic; patients usually respond well even with recurrence

-gamma and alpha interferon levels are decreased in patients w/ echinococcosis so addition of gamma therapy can help halt progression of disease

-overally prognosis usually grave

Definition
echinococcus multilocularis
Term
At present, what two helminth diseases require surgery?
Definition
-hydatid cysts and cysticercosis
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