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diphobothrium latum
taenia solitum
taenia sanginata
hymenolepsis nana
hymenolepsis dimunata
dipylidium caninum
These are what kind of cestodes? |
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echinococcus multiocularis |
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echinococcus granulosis
echinococcus multiocularis
these are what type of cestodes |
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cestodes or tapeworms belong to the phylum... |
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-known as flatworms
-dorsoventrally flattened and have solid bodies with no body cavity
-internal orans are imbedded in special tissue
-there are no respiratory or blood vascular systems
-life cycle of these organisms are generally indirect. they require at least one intermediate host to support larval development |
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Internal organs of cestodes are embedded in tissue called |
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Cestodes have an _________ host in which larval form lives and a __________ host in which adult worms live |
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Adult worm cestodes are characterized by segmented body parts:
Head or attachement portion is called ______ and has attachment mechanisms such as ______, ________, grooves or _____________.
reproductive structures contain uteri and intestine. |
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scolex, hooks, suckers, cutting plates |
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__________ of tapeworms is highly absorptive and even releases digestive enzymes at its surface from specialized microvilli called_______ |
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tegument (external surface), microtriches |
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Why must adult cestodes absorb nutrients through the tegument? where are waste products release? |
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B/c they have no mouth, digestive tract, or vascular system. Wast products are also excreted through the tegument |
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-ribbon like and flattened in cross section like a tape measure
-adult worm may range from a few millimeters to 20m in length
-anterior end of adult is modified for attachment to intestinal wall of the definitive host
-Scolex is usually equipped with four cup shaped suckers and some species also have a crown of hooks on the scolex to aid in attachment |
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Characteristics of cestodes |
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Adult cestodes live in ________________ of vertabrate definitive host, wheras larval stage inhabits ________ of intermediate host |
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Usually equipped with four cup shaped suckers and some species also have a crown of hooks on this to aid in attachment |
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entire body of tapeworm is termed |
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cestodes body consist of segments called |
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In cestodes, each tapeworm is __________ |
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Reproductive organs in each proglottid mature gradually so the proglottids towards the terminus... |
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have fully developed reproductive organs and the uterus is filled with fertilized eggs |
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proglottids break off from the chain are expelled... |
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-an embryo seen with tapeworm eggs
-bears 6 tiny hooklets that facilitate entry of the embryo into the intestinal mucosa of the intermediate host
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where does the embryo go after it hatches from the eggshell |
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migrates through the intestinal wall and goes to a specific tissue site |
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-broad fish tapeworm
-largest tapeworm affecting man (10m or more)
-infection is obtained by eating raw fish |
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epidemiology of diphyllobothrium latum |
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minimal infection is usually picked up when large segments of worm are passed in the stool |
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-unembryonated eggs passed in feces
-eggs embryonate in water
-coracidia hatch from eggs and are ingested by crustaceans
-procercoid larvae in body cavity of crustaceans
-crustacean ingested by fish, procecroid larvae develops into plerocercoid larva
-human ingests raw or undercooked fish
-adults in small intestine
-proglottids release immature eggs |
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-identification of UNembryonated operculated eggs having an ab-opercular knob
-eggs passed in stool
-eggs measure 58-76um by 40-51 um
-eggs are often confused with the eggs of paragonamus westermani
-identification of worm segments passed in stool
-the characteristic morphology of the proglottid is that it is wider than it is long
-identification of the worm scolex (2 grooves) |
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-cow is the intermediate host
-infection obtained from eating undercooked infected beef |
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-minimal except for mild GI disturbance
-sparganosis will occasionally occur when man is infected with the egg and larvae encyst in various tissues including brain, but this is rare |
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-identification of eggs measuring 31-43um with radial pattern on the egg wall
-identification of adult worm (up to 5m long)
-scolex has 4 suckers for attachment
-proglottids with 15-20 uterine branches are also diagnostic |
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-gets its name since the pig is the intermediate host
-man may be definitive host by eating infected pork with man being the host to adult worm
-man may be intermediate host by ingesting eggs and becoming the host to the larval stage of the parasite
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-minimal symptoms when man is the host to the adult worm which lives in the intestine
-cystercosis
-man ingest eggswhich produce larvae that migrate to various host tissues including the brain
-here they encyst and stimulate vigorous inflammatory response
-lesions eventually are fibrosed off and calcify
-patients have seizures and other CNS symptoms during the acute inflammation period and after lesions calcify
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-egss in stool have thick walls with radical striations
-adult wom parts are also diagnostic
-scolex characterized by crown of hooks and 4 suckers
-proglottids shed in stool that have 7-13 uterine branches
-adult worms reach up to 3m long |
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-infection by ingestion of eggs or by igestionn of beetles with cystecerci
-worldwide problem
-most common tapeworm infection is seen in children
-infects rat and mice, rarely seen in humans
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Hymenolepsis nana and hymnolepsis diminuta |
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-infection well tolerated with very few symptoms |
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hymenolepsis nana and hymenolepsis diminuta |
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-eggs in stool are thin shelled, have six hook oncosphere and polar filaments
-measures 30-47um and 60-79 um
-scolex has 4 suckers with hooklets- rarely see adult worm in stool |
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Hymenolepsis nana and hymenolepsis diminuta |
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-infects children with close dog/cat contact
-gravid proglottids or membrane bound egg packs are the diagnostic forms
-each egg measures 25-40um and contain six hooked oncosphere |
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-very small tapeworm (3-5 segments)
-the dog is the primary host, humans are accidental hosts
-dogs shed infective cysts in stool
-sheep or other herbivores ingest the cysts which hatch and infect tissues
-infection in humans results from eating infected tissues or eggs
-echinococcus hatches in the bowel and then migrate from the intestine to seed more tissues where cysts form containing infective scolexes |
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echinococcus granulosus (hydatid cyst) |
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-diagnosis generally made based on serology
-diagnosis may also be made on the identification of the short tapeworms in the hydatid sand or biopsy |
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echinococcus granulosus (hydatid cyst) |
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-causes alveolar hydatid cyst disease
-most lethal form of helminthic diseases with radical surgery still being the only curative therapy
-most cases are diagnosed in rural residents suggesting direct or indirect contact with fecal material from foxes and dogs
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echinococcus multilocularis |
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-adult worm 1.2-3.7 m
-eggs similar to taenia species and very resistant to cold
-cyst composed of many irregular cavities with little or no fluid, rare or no free scolexes and often central necrosis and cavitation of the lesion
-definitive host tends to be dogs, foxes, and cats and wolves while the intermediate host have been identified as field mice, house mice, squirrels and shrews. |
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echinococcus multilocularis |
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-found in tissues, liver being most common
-disease may resemble a slowly growing carcinoma and may present symptoms of intrahepatic hypertension
-there may be hepatosplenomegaly, splenomegaly, jaundice and ascites |
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echinococcus multilocularis |
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diagnosis of alveolar hydatid cyst disease may be difficult unless there is a presumptive diagnosis made based on history
diagnosis can be missed on autopsy
serology can be helpful
PCR developed for specific m-RNA from fine needle bioposy |
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Echinococcus multilocularis |
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-surgical removal of cyst is almost impossible due to no limiting capsule
-mebendozale is parisitostatic; patients usually respond well even with recurrence
-gamma and alpha interferon levels are decreased in patients w/ echinococcosis so addition of gamma therapy can help halt progression of disease
-overally prognosis usually grave |
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echinococcus multilocularis |
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At present, what two helminth diseases require surgery? |
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-hydatid cysts and cysticercosis |
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