Term
Given the etiology, name the Coagulation Disorder associated with it:
Sex-linked DECREASED in Factor VIII:C, seen in males from carrier moms.
VIII:vWF NORMAL & Platelet Function NORMAL |
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Definition
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Term
Given the etiology, name the Coagulation Disorder associated with it:
Autosomal deficiency of VIII:C & VIII:vWF. Seen in Males & Females.
Type 1 has a variably reduced level of vWF & VIII |
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Definition
| von Willebrands Coagulation Disorder |
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Term
Given the etiology, name the Coagulation Disorder associated with it:
Sex-linked deficiency of factor IX |
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Definition
| Hemophila B (Christmas Disease) |
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Term
Given the etiology, name the Coagulation Disorder associated with it:
Inappropriate, uncontrolled fibrin formation throughout the body from damage to endothelial cells |
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Definition
| DIC / Consumption coagulopathy |
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Term
| What is the most common of all of the single factor genetic deficiencies? |
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Definition
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Term
| What is the most common type of von Willebrands coagulation disorder? |
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Definition
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Term
What does the following suggest:
1% factor VIII activity |
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Definition
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Term
What does the following suggest:
5-12% factor VIII activity |
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Definition
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Term
What does the following suggest:
3-5% factor VIII activity |
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Definition
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Term
| Hemophilia A Carriers have _____ factor VIII Activity |
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Definition
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Term
| What tests would you use to diagnose Hemophilia A? |
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Definition
Factor VIII Assay
INCREASED PTT
NORMAL PT |
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Term
True or False:
Hemophilia A will have an INCREASED PTT & a NORMAL PT |
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Definition
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Term
True or False:
When considering Hemophilia A, the Factor assay will correct with Absorbed Plasma |
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Definition
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Term
True or False:
When considering Hemophilia A, the Factor assay will NOT correct with Aged Serum |
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Definition
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Term
True or False:
When considering Hemophilia A, the Factor assay will correct with Aged Serum |
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Definition
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Term
True or False:
When considering Hemophilia A, the Factor assay will NOT correct with Absorbed Plasma |
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Definition
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Term
Given the clinical representation, name the Coagulation Disorder:
Severe bleeding, especially in joints or after trauma; Carriers have NO symptoms and a NORMAL PTT |
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Definition
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Term
| What test will distinguish Hemophilia A from vWD? |
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Definition
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Term
| How should/would you treat Hemophilia A? |
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Definition
| Factor VIII (AHF) concentrate or Cryo |
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Term
True or False:
AHF is safer than cryoprecipitate because the AHF concentrate can be virus inactivated. |
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Definition
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Term
Given the clinical representation, name the Coagulation Disorder:
Mucosal bleeding, bruising, bleeding after hemostatic challenge |
|
Definition
| von Willebrands Coagulation Disorder |
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Term
Given the clinical representation, name the Coagulation Disorder:
Similar to hemophilia A, but not as Severe |
|
Definition
| Hemophilia B (Christmas Disease) |
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Term
Given the clinical representation, name the Coagulation Disorder:
Life-threatening thrombosis and bleeding |
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Definition
|
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Term
| If bleeding warrants, how should/would you treat von Willebrands Coagulation Disorder? |
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Definition
| Desmopressin (DDVAP) or Cryoprecipitate |
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Term
| Why would you use Cryoprecipitate to reat von Willebrands Coagulation Disorder? |
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Definition
| Cry INCREASES Factor VIII activity higher than would be expected |
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Term
| How would/should you treat Hemophilia B (Christmas Disease)? |
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Definition
| Factor IX Concentrate, Prothrombin Complex Concentrate (PCC), or Fresh Frozen Plasma (FFP) |
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Term
| With Coagulation Disorder is associated with sepsis, obstetrical complications, trauma, and malignancies? |
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Definition
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Term
| How would/should you treat DIC? |
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Definition
| Support therapy, heparin, fibrinolysis inhibitors, and Cryo to restore fibrinogen. |
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Term
| What will the PT and PTT be for von Willebrands Coagulation Disorder? |
|
Definition
Slightly INCREASED PTT
NORMAL PT |
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Term
| What will the BT be for von Willebrands Coagulation Disorder? |
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Definition
|
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Term
| What test would you perform, other than PT, PTT, & BT, to diagnose von Willebrands Coagulation Disorder? |
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Definition
|
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Term
True or False:
There will be NO platelet aggregation with ristocetin for von Willebrands Coagulation Disorder. |
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Definition
|
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Term
| What will the PT & PTT be for Hemophilia B (Christmas Disease)? |
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Definition
|
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Term
| What other test would you use to diagnose Hemophilia B (Christmas Disease)? |
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Definition
|
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Term
True or False:
Hemophilia B (Christmas Disease) will Correct with Aged Serum |
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Definition
|
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Term
True or False:
Hemophilia B (Christmas Disease) will NOT Correct with Absorbed Plasma |
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Definition
|
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Term
True or False:
Hemophilia B (Christmas Disease) will NOT Correct with Aged Serum |
|
Definition
|
|
Term
True or False:
Hemophilia B (Christmas Disease) will Correct with Absorbed Plasma |
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Definition
|
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Term
| What will you see on the blood smear of a DIC Positive Patient? |
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Definition
|
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Term
| What will the D-Dimer test be for a patient who is Positive for DIC? |
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Definition
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Term
| What will the Fibrinogen and Platelet Count be for a patient who has DIC? |
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Definition
DECREASED Fibrinogen
DECREASED Platelet Count |
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Term
| What will the PT & PTT be for a patient who has DIC? |
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Definition
INCREASED PT
INCREASED PTT |
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Term
| What will the TT & FSP be for a patient who has DIC? |
|
Definition
INCREASED TT
INCREASED FSP |
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