Shared Flashcard Set

Details

heme/onc
heme/onc medicine module
15
Medical
Professional
04/11/2008

Additional Medical Flashcards

 


 

Cards

Term
megaloblastic anemia
Definition

pathophys- disturbance in dna synthesis

morphology- oval macrocytes, teardrop polkilocytosis, hypersegmented polys 

Term
iron deficiency
Definition

pathophys- disturbance in hgn synthesis (lack or iron)

morph- hypochromic, microcytic 

Term
hereditary spherocytosis
Definition

pathophys- membrane defect

morph- spherocytes 

Term
hereditary elliptocytosis
Definition

pathophys - membrane defect

morph - elliptocytes 

Term
hemoglobin c dz
Definition

pathophys - abnormal globin chain

morph - target cells, rhomboid crystals (HgbC) 

Term
acanthocytosis
Definition

pathophys - membrane lipid defect (abetalipoproteinmemia)

morph - irregular spiculation (similar to spur cells of liver dz) 

Term
DIC, TTP, heart valve prothesis sequela
Definition

pathophys - mechanical damage to erythrocytes

morph - schistocytes 

Term
sickle cell dz
Definition

pathophys - abnormal globin chain

morph - sickle cells 

Term
thalassemia
Definition

pathophys - disturbance in hemoglobin synthesis (defect of globin chain)

morph - hypochromic, microcytic, poikilocytosis, basophilic stippling 

Term
myelophthisic anemia
Definition

pathophys - marrow replacement of infiltration

morph - teardrop poikilocytosis, immature wbc and rbc, large platelets 

Term
anemia of chronic dz
Definition

pathophys - block in utilization of storage iron

morph - normochromic, normocytic to mild hypochromic, microcytic 

Term
sideroblastic anemia
Definition

pathophys - defect in porphyrin and heme synthesis

morph - bimorphic population (normal and microcytic), pappenheimer bodies 

Term
anemia of renal dz
Definition

pathophys - multifactoral

morph - burr cells (uniform marginal scalloping) 

Term
autoimmune hemolytic anemia
Definition

pathophys - rbc destruction mediated by antibodies

morph - spherocytes 

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