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Histology Exam 1
Lecture 4 (Epithelium)
20
Other
Not Applicable
06/06/2008

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Term
characteristics of epithelium
Definition
form tight sheets
cover external body surface
all substances entering/leaving body must cross sheet
vital role in immune/inflammatory response
1st line of defense
no blood vessels, but has nerves
Term
nonkeratinized epithelium
Definition
have nuclei
protection against dessication, abrasion, chemical and bacteria
found in esophagus, vagina, cornea and oral cavity
Term
keratinized epithelium
Definition
no nuclei
protects against environment, dessication, abrasion, chemical and bacteria
found in epidermis of skin, some regions of gingiva and hard palate
Term
apical domain
Definition
free surfaces of cell
faces internal space/lumen or external environment
has microvilli, cilia, and sterocilia
Term
microvilli
Definition
contain microtubules
project into lumen
increase surface area
foundin small intestine and corneal epithelial cells
Term
cilia
Definition
contain microtubles and proteins that allow movement/beating
move particles along lumen
found in oviduct and respiratory tract
Term
stereocilia
Definition
contain microfilaments
found in hair cells of middle ear and epididymal duct of male testes
Term
lateral domain
Definition
cell-cell contact
has occluding junctions, anchoring junctions,and communicating junctions
Term
occluding junctions or tight junctions
Definition
located where two cells touch near lumen
regulate paracellular pathway/movement of ions btwn cells
Term
anchoring junctions
Definition
desmosomes/macula adherens and zonula adherens
Term
desmosomes
Definition
aka macula adherens
connect outside of cell to keratin inside cell
Term
zonula adherens
Definition
zone of adhesion btwn cells
holds cells together by connecting outside of cell to actin filaments inside cell
Term
communicating junctions
Definition
gap junction
Term
gap junction
Definition
channels in plasma membrane
Term
basal domain
Definition
contact basal lamina
Term
hemidesmosomes
Definition
anchoring junction found only when cell touches basal lamina
connects basal lamina outside cell to keratin intermediate filaments inside cell
Term
epidermal ridges/rete pegs
Definition
found in some part of gingiva and hard palate
columns of epithelium cells grow into connective tissues
surrounded by basal lamina
function to hold sheet to connective tissues in areas of high friction or abrasion
Term
epidermal ridges/rete pegs
Definition
found in some part of gingiva and hard palate
columns of epithelium cells grow into connective tissues
surrounded by basal lamina
function to hold sheet to connective tissues in areas of high friction or abrasion
Term
cytoskeleton of epithelial cells
Definition
actin
microtubules
keratins
Term
keratins
Definition
aka intermediate filaments, cytokeratins, tonofiliments, and tonofibrils
epithelial cell disease may involve problems w/this function
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