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Monocyte
Monocytes are the blood and bone
marrow located precursors of
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–Sheets of cells without intercellular connective tissue, only extracellular fluid
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–Rest on a BASEMENT MEMBRANE
–Avascular
– nutrition by diffusion of nutrients from the vascularized connective tissue seated under the basement membrane
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Term
Specialized layer of extracellular matrix materials (Type IV collagen)
Separates the epithelium from the underlying tissue
Nutrients, O2 and metabolites must diffuse through the basement membrane
Adhesion interface
Selective barrier against cell displacement.
Control cell organization, differentiation, cell polarity, regenereration
Molecular sieve |
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Integrin beta1 staining of formalin fixed, paraffin embedded skin. Note membrane staining of basal cells and basement membrane.
� |
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Squamous cells
Plateepitel |
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Columnar cells
Sylinderepitel |
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Cuboidal cells
Kubisk epitel |
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–Synchronized movement
–Lungs: transportation of mucus and dust particles towards the farynx (svelget)
–Egg transport in the uterin tubes
–Sperm transport to epididymis (bistestikkel)
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–Increased surface for absorption; space for transport molecules
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Squamoums epithelium
(Plateepitel) |
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Definition
Function: One layer: Barrier, passive absorption,
Stratified: Barrier, protective, areas of constant abrasion
[image]flat, unkaretinized stratified
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Cuboidal epithelium
(Kubisk epitel) |
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Definition
[image]
In sweat glands, breast and male urethra
Cube shaped, centrally placed nucleus
Barrier, absorption, secretion, transcellular active transport
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Columnar epithelium
(Sylinderepitel) |
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[image]
Parts ofurethra, conjuctiva, ductsofsome glands
Columnar, basally located nucleus. Apical specialisations: cilia, microvilli, stereocilia
Barrier, absorbtion, secretion, transcellular transport
Cilia: transport
Microvilli: suraface
Stereocilia: suraface
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Pseudostratified epithelium
(Pseudolagdelt
epitel) |
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[image]
Columnar, basally located nucleus,
(un-)ciliated
Barrier, absorbtion, secretion, transcellular transport
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| Stratified Squamous Epithelium |
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[image]
well suited for areas of the body subject to constant abrasion
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| Stratefied squamous epithelium |
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[image]
[image]
Simple cuboidal epithelium provide protection and may be active or passive
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| Psuedostratified epithelium |
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[image]
Function in secretion and absorption
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(wound contraction, scaring, shape of intestinal crypts and villi)
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| Intima, media, and advent |
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Mucosa
Columnarepithelium: mucus, bicarbonate
Lamina propria with glands ofacidproducingcells (parietalcells) and pepsinogen-producingcells (chief cells)
Muscularismucosawithinnercircular and outer longitudinal smoothmusclelayers
Submucosa
Looseconnectivetissuewith large vessels and nerves
Muscularisexterna
Inneroblique, middlecircular and outer longitudinal smoothmusclelayers
Serosa
The peritoneum – connectivetissue and mesothelium
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| Small intestine (picture) |
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Definition
[image]
1.Goblet cell.
2.Lamina propria
3.Lieberkuhn gland
4.Paneth cells
5.Muscularis mucosa
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| Small intestine description |
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Mucosa
Simple columnarepitheliumEnterocyteswithmicrovilli
Mucouscells (Gobletcells)
Panethcells (Eosinophilic granula)
Lamina propria - Glands
Muscularismucosa- Circular and longitudinal layers
Submucosa
looseconnectivetissuewithvessels and nerves.
Glands only in duodenum.
Muscularisexterna
Innercircular and outer longitudinal layers
Serosa
The peritoneum
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Mucosa(noplicacirculares, novilli)
Simple columnarepitheliumEnterocyteswithmicrovilli
Abundant mucouscells (Gobletcells)
Lamina propria – Lieberkuhn glands, lymphoidfolicles
Muscularismucosa- Circular and longitudinal layers – smoothmuscle
Submucosa
looseconnectivetissuewithvessels and nerves.
Muscularisexterna(smoothmuscle)
Innercircularlayer
Outer longitudinal layer is incomplete
and forms threeseperate longitudinal
ribbons
Serosa
The peritoneum
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[image]
Stratified, unkeratinized squamous epithelium
Simple columnar epithelium
Simple columnar epithelium, microvilli
Simple columnar epithelium, microvilli
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| Simple cubodial epithelium, |
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Ciliated pseudostratified epithelium
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| Stratified squamous epithelium |
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From left to right, top row then bottom row
Neutrophil, Monocyte, Eosinophil
Basophil, lymphocyte |
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