Term
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Definition
| HIV antibody positive with CD4 count <200 or CDT4 cells consitute <14% total lymphocytes |
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Term
| What has the highest risk of exposure to HIV? the lowest? |
|
Definition
highest-transfusion of contaminated blood products
lowest-needle stick and sexual transmission |
|
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Term
| What is the most common route of transmission worldwide? |
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Definition
|
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Term
| What were the majority of occupational exposure to HIV caused by? |
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Definition
|
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Term
| which coreceptors play an important role in the fusion of the virus to the host cell? |
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Definition
|
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Term
| What serves as a strong independent predictor of the progression to AIDS? |
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Definition
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|
Term
| What serves as a great way to assess the current immunologic status? |
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Definition
|
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Term
| What is the HIV RNA levels in most acute cases? |
|
Definition
| >50,000 copies/ml, most >300,000 copies/ml |
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Term
| CD4 counts greater than what are indicated for good response to vaccines? |
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Definition
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Term
| What are the 4 classes of antiretroviral therapy meds? |
|
Definition
1) nucleoside reverse transcriptase inhitors (NRTIs)
2) nonnucleoside transcriptase inhibitors (NNRTI)
3) protease inhibitors
4) fusion inhibitors |
|
|
Term
| What is the recommended HIV tx regimens? |
|
Definition
1) combo of 2 NRTIs plus a protease inhibitor
2) 2 NRTIs plus NNRTI
3) 2 NRTIs plus 2 protease inhibitors |
|
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Term
| What regimens should be given for occupational exposure prophlaxis? |
|
Definition
1) Xidovudine w/ either lamivudine or emtrictabine
2) Tenofovir with either lamivudine or emtrictabine |
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|
Term
| when should C-sections be considered with HIV? |
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Definition
| when RNA levels are >1000 at time of delivery |
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