Term
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Definition
-basic unit of structure&function in body
-highly organized molecular factory
*each cell maintains homeostasis |
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Term
| 3 Main Components of cells |
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Definition
Plasma Membrane
Cytoplasm (intersitial fluid)
Organelles |
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Term
| Function of the Plasma Membrane |
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Definition
-barrier between extracellular and intracellular enviornments
-determine movement of substances into and out of the cell (semi-permeable)
-recognition of and communication with other cells |
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Term
| Plasma Membrane composed of...(3) |
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Definition
*Lipids, 90-99% molecules (50% wt)
*Proteins, 1-10% molecules (50% wt)
*Carbohydrates (recognition of cell), rest, space leftover, glycolipids and glycoprotein, acts as covering |
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Term
Plasma Membrane:
Fluid-mosaic model |
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Definition
-formed by double layer of phospholipids
*shifts around
*selectively permeable
*restricts passage of polar compounds |
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Term
Plasma Membrane:
Purpose of Cholesterol |
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Definition
Stabilizes, w/o cholesterol everything could move freely
- more cholesterol=more rigid, less fluidity |
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Term
Plasma Membrane:
Purpose of Protein |
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Definition
-provide structural support
-serve as transporters, enzymes, receptors, and identity markers |
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Term
Plasma Membrane:
Purpose of Carbohydrates |
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Definition
in form of Glycoproteins and Glycolipids, part of outer surface
- polarity creates layers of water around cell |
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Term
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Definition
way cells move large molecules and particles across plasma membrane
- some cells use Phagocytosis to take in particulate matter
ex: white blood cells and macrophages |
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Term
Bulk Transport:
Endocytosis |
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Definition
- take in large compounds
*membrane invaginates to take a vesicle of extracellular substance
~Pinocytosis is non-specific intake |
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Term
Bulk Transport:
Receptor-mediated endocytosis |
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Definition
-uses receptors to take in specific compounds
1) plasma membrane pit forming
2) membrane pouching inward
3) vesicle forming
4) vesicle inside cell |
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Term
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Definition
Vesicle
fuse w/ membrane
move out of cell |
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Term
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Definition
| enters cell by receptor-mediated endocytosis |
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Term
| Familial Hypercholesterolemia |
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Definition
genetic
-high blood cholesterol
-no receptors or defective receptors |
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