Term
Cell membrane structures and functions |
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Definition
Membranes form fluid body compartments
Membranes are barriers and gateways
Membranes distribute water and solutes in cells and the body
Chemical and electrical imbalances
Membrane permeability and changes |
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Term
Fluid Mosaic Model Contains |
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Definition
Phospholipids
Integral Proteins
Peripheral Proteins
Glycoproteins - MHC and Glycolipids
Cholesterol |
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Term
Inorder for something to pass through the phospholipid bilayer |
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Definition
It needs to be very small
Needs to be a lipid - nonpolar |
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Definition
are gate, channel pores
5 protein glob
can pass medium size molecular weight
water - polar molecules
ions |
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Term
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Definition
1. Protein hormones bond to the peripheral protein causing a shape change
2. When the integral protein changes shape the internal 3. peripheral protein changes shape
4. Adenylate Cyclase converts ATP
ATP converts to CAMP + PO4 |
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Definition
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When the internal peripheral protein changes shape |
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Definition
Major Histocompatability Complex |
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Term
3 types of passive transport |
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Definition
1. Simple diffusion
2. Osmosis
3. Facilitated diffucion (mediated transport) |
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Term
3 types of active transport |
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Definition
1. co-transport
2. vesicular transport
3. receptor mediated transport |
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Term
Concentration from high to low across a semi permiable membrane, no external energy needed? |
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Definition
Simple diffusion is from high to low concentration |
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Term
Properties of simple diffusion |
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Definition
uses energy of the concentration gradient
movement occurs till equilibrium is reached
direct correlation to temp
indirect correlation to molecule size
slower diffusion with increased distance
lipophilic molecules can diffuse through the phospholipid bilayer |
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Term
In ..... diffusion the protein gate helps push the molecule across the membrane. |
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Definition
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Definition
The number of particles in a solution |
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Term
The movement of water from high concentration to low concentration |
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Definition
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Low concentration of particles to high concentration of particles |
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Definition
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Definition
Moves from low concentration to high concentration
ATP is needed
creates a state of disequilibrium
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Term
1 degree active transport |
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Definition
ATP energy directly fuels transport
uniport and antiport |
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Term
2 degree indirect active transport |
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Definition
uses concentration gradient for energy
symport and antiport |
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Term
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Definition
molecules are carried in same direction
examples Glucose and Na |
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Definition
Molecules are carried in opposite directions |
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Term
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Definition
Movement of macromolecules across cell membrane |
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Term
Properties of Vesicular Transport |
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Definition
1. Phagocytosis - macrophage or phagocytes
2. Pinocytosis - cell drinking
3. Receptor mediated endocytosis - down regulation
4. Exocytosis |
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Properties of Phagocytosis |
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Definition
requires energy
cell engulfs particle into vesicle via pseudopodia formation
vesicles formed are larger than those formed by endocytosis
phagosomes fuse with lysosome |
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Definition
nonselective - pinocytosis for fluids and dissolved substances
selective - receptor mediated endocytosis via clathrin coated pits. ie. LDL cholesterol and familial hypercholesterolemia |
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Term
Receptor Mediated Endocytosis |
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Definition
No 1. uptake method in most cells
receptors and the substance is internalized
clathrin coated vesicle
down regulated |
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Term
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Definition
intracellular vesicle fuses with cell membrane
requires ATP and Ca2+
used on waste removal |
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