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Human Physiology Test 5
Digestive System
83
Biology
Undergraduate 4
05/05/2013

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Term
What are the 5 process of the digestive system?
Definition
Ingestion
Digestion
Absorption
Compaction
Defecation
Term
What is the selective intake of food?
Definition
ingestion
Term
What is the mechanical, chemical disassembly of food into usable form?
Definition
digestion
Term
What is the uptake of molecules into epithelial cells, then into blood and lymph?
Definition
absorption
Term
What is the absorption of water and consolidating of indigestible residue into feces?
Definition
compaction
Term
What is the elimination of feces?
Definition
defecation
Term
What do digestive enzymes convert polysaccharides into?
Definition
monosaccharides
Term
What do digestive enzymes convert proteins into?
Definition
amino acids
Term
What do digestive enzymes convert fats into?
Definition
monoglycerides and fatty acids
Term
What do digestive enzymes convert nucleic acids into?
Definition
nucleotides
Term
What process do digestive enzymes use?
Definition
hydrolysis
Term
What nutrients are in absorbable forms?
Definition
vitamins, free amino acids, minerals, cholesterol, and water
Term
How much can the stomach hold after a typical meal?
Definition
~1.0-1.5 L
Term
What begins the chemical digestion of protein and fat?
Definition
the stomach
Term
What is a soupy mixture of semi-digested material?
Definition
chyme
Term
When does most digestion occur?
Definition
after the chyme passes to the small intestine
Term
Stretch stimulation and peristaltic contractions of swallowing are both examples of what?
Definition
myenteric reflexes
Term
Parasympathetic stimulation of digestive motility and secretion is an example of what?
Definition
vagal reflexes
Term
What are the 3 things that contribute to GI regulation?
Definition
neural control, hormones, and paracrine secretions
Term
WHere does all blood drained from the stomach and intestines go?
Definition
enters the hepatic portal of the liver and returns to heart
Term
What does the small intestines absorb?
Definition
Everything because it has no barriers
Term
What are the 6 types of gastric glands?
Definition
Parietal cells
Chief cells
Gastric Juice
Enteroendocrine cells
Regenerative (stem) cells
Mucus Neck (goblet) cells
Term
What secretes hydrochloric acid, intrinsic factor, and the hunger hormone (ghrelin)?
Definition
parietal cells
Term
What secretes gastric lipase and pepsinogen (inactive pepsin)?
Definition
chief cells
Term
What has G-cells and paracrines?
Definition
enteroendocrine cells
Term
What does serotonin do?
Definition
increase motility
Term
What is an example of a paracrine?
Definition
serotonin
Term
How much gastric juice is produced in a day?
Definition
~2-3 L/day
Term
What is the pH of HCl in gastric juice?
Definition
<1
Term
What are the 4 functions of HCl?
Definition
Breaks up CT and plant cell walls
Convert ingested Fe3+ to Fe2+
Activates pepsin
Nonspecific immunity
Term
What is essential for the absorption of vitamin B12 by the small intestine?
Definition
intrinsic factor
Term
What does B12 prevent?
Definition
pernicious anemia
Term
What induces vomiting?
Definition
over stretching of the stomach/duodenum
chemical irritants
and visceral trauma, pain, or psych
Term
How does the stomach mucosa get replaced?
Definition
through mitosis
Term
How often does the stomach mucosa get replaced?
Definition
every 3-6 days
Term
What is gastric juice composed of
Definition
mainly water, HCl and pepsinogen
Term
What secretes mucus?
Definition
mucus neck (goblet) cells
Term
What divides rapidly and produces a continuous supply of new cells to replace the ones that die in the stomach?
Definition
regenerative (stem) cells
Term
Which gastric gland cell is the most numerous?
Definition
chief cells
Term
Where does the stomach receive parasympathetic nerve fibers from?
Definition
the vagus nerves
Term
Where does the stomach receive sympathetic fibers from?
Definition
the celiac ganglia
Term
What are the 3 ways the stomach is protected?
Definition
alkaline mucus coat
tight junctions
and
epithelial cell replacement
Term
How does the alkaline mucus coat protect the stomach?
Definition
it resists the action of acid and enzymes
Term
How do tight junctions protect the stomach?
Definition
prevents gastric juices from seeping between them and digestion the connective tissue of the lamina propria
Term
What can the breakdown of the protective mechanisms of the stomach result in?
Definition
inflammation and peptic ulcers
Term
Where are intestinal crypts located?
Definition
at the base of the villi
Term
What is another name for intestinal crypts?
Definition
crypts of Lieberkuhn
Term
What does the upper half of the crypt contain?
Definition
enterocytes and goblet cells
Term
What does the lower half of the intestinal crypts contain?
Definition
stem cells that replace the epithelial cells
Term
What clusters near the base of the intestinal crypts?
Definition
Paneth cells
Term
What secretes lysozyme, phospholipase, and defensins?
Definition
paneth cells
Term
What do defensins do?
Definition
defensive proteins that resist bacterial invasions of the mucosa
Term
Where are the duodenal glands located?
Definition
submucosa
Term
What secretes an abundance of bicarbonate-rich mucus that helps neutralize the HCl from the stomach?
Definition
duodenal glands
Term
Where is a large population of lymphocytes located?
Definition
throughout the lamina peoria and submucossa of the small intestines
Term
What do lymphocytes do?
Definition
intercept pathogens
Term
What are they called when lymphocytes are aggregated into conspicuous lymphatic nodules in the ileum?
Definition
Peyer patches
Term
What does chyme stimulate the release of?
Definition
secretin and cholecystokin
Term
What does chyme do?
Definition
stimulate the pancreas and gall bladder, and suppress gastric secretion
Term
What stimulates insulin secretion?
Definition
glucose-dependent insulin secretion (GIP)
Term
What are the 3 organs that provide the small intestines with secretions that are critical for digestion?
Definition
liver,
gallbladder,
and
pancreas
Term
How does the liver help with digestion?
Definition
produces bile
Term
How does the gallbladder help with digestion?
Definition
stores bile
Term
How does the pancreas help with digestion?
Definition
most digestive enzymes are created here
Term
What is the triad consist of?
Definition
small branch of hepatic artery,
small branch of hepatic portal vein,
and
bile duct
Term
What does the small branch of the hepatic artery do?
Definition
carry oxygenated blood to the liver cells
Term
What does the small branch of hepatic portal vein do?
Definition
carry blood from the GI tract
Term
What does the Bile Duct do?
Definition
collects and transports bild to hepatic ducts and gallbladder
Term
What parts of the triad passes over the hepatocytes of the sinusoids?
Definition
the hepatic artery and hepatic portal vein
Term
What is both an endocrine and exocrine gland?
Definition
pancreas
Term
What part of the pancreas is endocrine?
Definition
islets of Langerhans (1%)
Term
What part of the pancreas is exocrine?
Definition
ancinar cells (99%)
Term
What makes up the islets of Langerhans?
Definition
alpha cells and beta cells
Term
What releases glucagon which in turn increases blood glucose?
Definition
alpha cells
Term
What releases insulin which in turn decreases blood glucose?
Definition
beta cells
Term
What types of cells are present in diabetes?
Definition
beta cells
Term
What produces pancreatin?
Definition
acinar cells
Term
What are the pancreatic zymogens?
Definition
the enzymes trypsinogen and carboxypeptidase
Term
What does trysinogen do?
Definition
digests peptide bonds
Term
What does carboxypeptidase do?
Definition
removes amino acids one by one
Term
What pancreatic enzyme beings remainder of starch (50%) digestion?
Definition
pancreatic amylase
Term
What pancreatic enzyme is responsible for most of the fat digestion?
Definition
pancreatic lipase
Term
Which pancreatic enzyme digests RNA and DNA?
Definition
ribonuclease and deoxyribonuclease
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