Shared Flashcard Set

Details

Hypertension Beta Blockers
Hypertension Beta Blockers
30
Pharmacology
Professional
09/09/2012

Additional Pharmacology Flashcards

 


 

Cards

Term
What are beta blockers used for?
Definition

HTN

Post-MI

HF

Migraine Prophylaxis

 

First line use for HTN now being discouraged

Term

What is the primary alpha + beta blocking agent used for HF and HTN?

Definition
Carvedilol
Term
What other beta blocker is commonly used for HF and HTN?
Definition
Metoprolol XL
Term

Which beta blocker (that also increases nitric oxide) is indicated for HTN and used off-label for HF

Definition
Nebivolol
Term
Beta blockers with ISA activity?
Definition

CAPP:

 

Carteolol

Acebutolol

Penbutolol

Pindolol

Term
Betab blockers with Beta-1 selectivity?
Definition

AMEBBA:

 

Atenolol

Metoprolol

Esmolol

Bisoprolol

Betaxolol

Acebutolol

[image][image][image][image]

Term
Beta blockers with more lipid solubility have more what?
Definition

more CNS side effects; higher sedation, cognitive effects, depression with lipid-soluble agents

Term
Which beta blocker has high lipid solubility?
Definition
Propanolol
Term
Should carvedilol be taken with or without food?
Definition
With food (even the CR version)
Term
Are doses of Carvedilol CR equivalent to Carvedilol IR?
Definition

NO. Carvedilol is less bioavailable than Carvedilol IR, therefore, dose conversions are not me per mg

Term
Which beta blokcer is often used as first line for HTN in pregnancy?
Definition

Labetolol

 

Nifedipine also used. Methyldopa can be used and was used historicaly, but has many side effects

Term
What symptoms of hypoglycemia do beta blockers mask?
Definition

symptoms of shakiness and anxiety - this occurs mostly with the non-selective agents

Term
What symptoms of hypoglycemia do beta blockers not cover up?
Definition
sweating (diaphoresis) and hunger
Term
Which beta blocker is normally used for stage freight?
Definition
Propanolol
Term

Use caution with breathing problems (asthma, COPD). Choose beta - 1 selective agents, and keep at selective dosing

Definition
Statment. Not a question.
Term
Brand name for Atenolol?
Definition
Tenormin
Term
Betaxolol
Definition
Kerione
Term
Brand name for Metoprolol tartate
Definition
Lopressor
Term
Brand name for Metoprolol succinate ext release
Definition
Lopressor XL, Toprol XL
Term
[image]
Definition
Statement. Not a question.
Term
Brand name for Nebivolol?
Definition
Bystolic
Term
[image]
Definition
Statement. Not a question.
Term
Brand name for Propranolol?
Definition
Inderal LA, InnoPran XL
Term
How do ISA agents affect HR?
Definition
ISA agents do not decrease HR as much as others
Term
[image]
Definition
Statement. Not a question.
Term
Brand name for Carvedilol
Definition
Coreg, Coreg CR
Term
Decrease the dose of Carvedilol when heart rate < ____
Definition
55
Term
[image]
Definition
Statement. Not a question.
Term
Beta blockers can enhance the effects of ___ and ______
Definition

insulin and oral hypoglycemic

 

Term
Carvedilol's serum concentration is lowered by 70% by which drug?
Definition
rifampin
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