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Immumnohistochemistry, Basic immunology, organs and function
For test on 7/8
44
Histology
Not Applicable
07/07/2011

Additional Histology Flashcards

 


 

Cards

Term
Immunology
Definition
The study of immune system and its response
Term
Antigen
Definition
Any substance or cell capable of stimulating a immune response
Term
Epitope
Definition
Smallest unitof Antigen capiable of producing an immune response, size varys on type of Anitgen
Term
Antibody
Definition
Substance produced in the body that specifically conteracts the effects of the disease producing organism/material
Term
What will bind to the Antibody to form a complex?
Definition
Type T and B lymphocytes or an antibody
Term
What are Antibodies also called?
Definition
Immunoglobulins (are capable of a specific combination with an Antigen)
Term
Antibodies are produced by what type of lymphocyte?
Definition
B lymphocyte
Term
What does the Immune Sytem do?
Definition
Responsible for fighting off foreign material and infectious agents
Term
Where are the lymph nodes located?
Definition
Arranged in groups in various locations throughout the body
Term
How many lymphnodes can be in a group?
Definition
Groups can have anywhere from 3-100 individual nodes
Term
Where is the spleen located?
Definition
In the left upper hyochondriac region of the abdomen (protected by rib cage)
Term
What are the cervical lymph nodes responsible for?
Definition
Draining various parts of head and neck
Term
What is the epithelium of the tonsil?
Definition
Stratified squamous non-keratinizing
Term
Where are the Axillary Lymph nodes located?
Definition
the armpit
Term
What do the axillary lymph nodes do?
Definition
Drain upper extremities and breasts
Term
Where are the Tracheobronchial lymph nodes located?
Definition
Near trachea and larger bronchial tubes
Term
Where are the Mesenteric lymph nodes located?
Definition
Between the two layers of the perioneum that form the mesentery
Term
Where are the inguinal Lymph nodes located?
Definition
The groin area
Term
What do the Inguinal Lymph nodes do?
Definition
Drain the lower extermities and genital organs
Term
Where are the abdominal lymph nodes located??
Definition
Various locations of the abdominal cavity
Term
Where is the Thymus located?
Definition
Upper Thorax beneth the sternum
Term
Where is the Tonsils located?
Definition
The back of the throat
Term
What is the Palatine tonsils?
Definition
Tonsils
Term
What is the Pharyngeal tonsils?
Definition
Adenoids
Term
What is the Lingual tonsils?
Definition
Located at the base of the tongue
Term
Where is bone marrow found?
Definition
Found in the center of all long bones, sterum, ribs and pelvis
Term
What does blood consists of?
Definition

Red blood cells

Platelets

White blood cells

Term
(type of white blood cells) What is Neutrophils?
Definition
Ingest and kill pathogens (bacteria and fungus).  They die after ingesting and create pus
Term
(type of white blood cell) What is Eosinophils?
Definition
They have a role against parasites and hypersensitivity (allergic reactions), role in suppression of inflammation
Term
(type of white blood cell) What is Basophils?
Definition
Against parasites and allergica reactions.  Called mast cells, have heparin and hisamine.
Term
(type of white blood cell) What is a Monocyte?
Definition
Macrophages- ingest and kill microorganisms.  They survive after ingestion and become Anitgen presenting cells!  This means a portion of anitgen is expressed in the macrophages membrane and is recongized by lymphcytes. (memory cells!!)
Term
(type of white blood cell) WHat is lymphocyte?
Definition
T and B lymphocytes responsible for humoral and cell mediated immunity
Term
What does the Thymus produce?
Definition
T cells!
Term
What are T cells reponsible for?
Definition
Cell mediated immunity! And have sufaces markers that are specific to an individual antigen
Term
What are they types of T cells?
Definition
T-Helper(killer) T-Suppressor, and T-Cytotoxic
Term
Where are B- Cells produced?
Definition
Lymphoid organs
Term
What are B-cells responsible for?
Definition
Antibody production = Humoral Immunity
Term
What do B- cells produce?
Definition
Antibodies that are called plasma cells
Term
What happends after an immune response? (having to do with B-cells)
Definition
A few plasma cells remain and become memory cells! Ready to start another response if the same antigen enters the body again.
Term
What is the Epithelium of the endothelium of lymphatic vessels?
Definition
Simple squamous epithelium
Term

How the immune system destoys a virus..

 

Definition

1. White blood cells (macrophages) encounter a virus

2. Macrophage is a phagocytic cells and consumes the virus.

3. Other virus molecules infect nearby cells

4. The macrophages digest the virus and display the antigen on its surface

5. The nearby cells are now infected

6. T-helper cells revongnize the anitgen and binds to the macrophage

7.The binding of the T-helper simulates the production of a intercellular communication

8. The chemical produced then instructs other T-cellers and the Tcell killer to multiply

9.The more T-helper cells that release substances cause the B-cells to multiply and produce antibodies

10.  The killer T-cells being shooting holes in the host cells that have the virus

11.The anitbodies realased by B-Cells bind to the antigens

12. Signals blood components, complements, to poke holes in virus.

13. As the infection is under control the activated T-B cells are turned off by suppressor T-Cells

14. Few memory cells stay behind incase the virus attacks again

Term
How is lymphatic tissue classified?
Definition

Diffuse lymphoid tissue (GI tract)

Dense Lympoid tissue (lymph nodes, peyers patches)

Term
Cells responsible for phagocytces..
Definition
Nuetrophils and Macrophages
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