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Immunity
Immunity
20
Anatomy
Undergraduate 1
03/23/2012

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Cards

Term
2 types of immunity
Definition
innate (nonspecific) and adaptive
Term
How does innate immunity function
Definition
Functions the same each time
Term
First line of innate immunity
Definition
Physical barries (skin, mucuous membrane) and chemical barriers (digestive enzymes)
Term
2nd line of innate immunity
Definition
Fever, Inflammation, chemotaxis, cytokines, phagocytosis, natural killer cells, interferons
Term
how many lines of innate immunity defense are there
Definition
2
Term
What does a fever do
Definition
kills off pathogens that grow better at cooler temps
Term
What do Natural Killer Cells do?
Definition
They release perforins which target cancer and virus cells and cause them to lyse
Term
What do interferons do
Definition
They stop viral replication and activate microphages and NK cells
Term
What is chemotaxis
Definition
method by which leukocytes respond to damaged tissues
Term
How is chemotaxis achieved
Definition
by damaged tissues releasing cytokines which are chemical messengers
Term
What is the process by which WBCs squeeze through capillary slits in reponse cytokines
Definition
diapedsis
Term
what is the third line of defense
Definition
Adaptive responses
Term
What is in adaptive repsonses
Definition
anti-body mediated responses and cell mediated repsonses
Term
what is antibody mediated repsonse in response to
Definition
specific invading antigen
Term
Substance that stimulates adaptive immunity
Definition
Antigen
Term
How does antibody mediated immunity work
Definition

On the first exposure of the antigen to the B Cell, the B Cell divides and grows into plasma cells, which release antigens, and Memory B cells.

 

On the Second exposure, the memory B cells  rapidly divide and produce antigens and a bigger response

Term
What type of immunity results from a vaccine being given to a person which exposes them to a pathogen and then the body produces antibodies for that pathogen
Definition
Active immnity
Term
What type of immunity results from antibodies being recieved from another source, not producin them themselves
Definition
Passive Immunity
Term
How does cell mediated immunity work
Definition
A  macrophage captures the non-self cell.  then a helper T cell release's cytokines, which causes cytotoxic T cells to destroy the nonself cell through chemotaxis
Term
When is cell mediated immunity used over antibody mediated immunity.
Definition
When the invader is inside the cell because antibodies cant cross the plasma membrane
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