Term
a _ stem cell gives rise to immune system cells. it first gives rise to 2 other cells |
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Definition
pluripotent
common lymphoid progenitor myeloid progenitor |
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Term
NK cells share their lineage most closely with what other cell of immune system? |
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Definition
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Term
common lymphoid progenitor --> ? |
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Definition
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Term
common myeloid progenitor --> (6) |
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Definition
megakaryocyte RBC monocyte eosinophil basophil neutrophil |
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Term
hallmark of HIV infection is decrease in what kind of cells? |
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Definition
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Term
reticuloendothelial system 3 roles |
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Definition
-phagocytosis -cytokine production to recruit other inflammatory cells -peptide antigen presentation |
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Term
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Definition
monocytes macrophages dendritic cells Langerhans cells glial cells |
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Term
dendritic vs. langerhans cells --found where? |
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Definition
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Term
mast cells are the _ counterparts of _ |
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Definition
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Term
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Definition
monocytes macrophages neutrophils |
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Term
the first cells recruited to inflammatory sites |
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Definition
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Term
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Definition
neutrophils monocytes macrophages |
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Term
_ are phagocytes that are big on chemotaxis |
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Definition
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Term
"professional" antigen presenting cells (3) |
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Definition
macrophages dendritic cells B cells |
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Term
defense against parasites is by (3) |
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Definition
eosinophils basophils mast cells |
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Term
eosinophils defend against parasites and participate in _ _ reactions |
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Definition
cytotoxic hypersensitivity |
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Term
neutrophils do or don't do antigen presentation? |
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Definition
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Term
basophils/mast cells have receptors for _ antibodies |
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Definition
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Term
basophils/mast cells have granules that contain (2) |
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Definition
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Term
basophils / mast cells degranulate when... |
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Definition
cell-bound IgE antibodies are cross-linked by antigens |
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Term
macrophages are differentiated _ |
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Definition
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Term
_ provide a link between innate and adaptive immunity |
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Definition
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Term
dendritic cells present antigen to both |
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Definition
T helper T cytotoxic cells |
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Term
B cell class switching from Ig _ to ... is thought to require what cells' assistance? |
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Definition
IgM --> IgG, IgA, or IgE T helper cells |
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Term
every mature T cell expresses the _ molecule, (which is associated with the TCR) |
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Definition
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Term
~ are the primary regulators of T cell- and B cell- mediated responses |
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Definition
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Term
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Definition
B lymphocytes to become antibody-producing cells
effector T cells in cell-mediated immunity |
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Term
T helper cells express CD _ |
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Definition
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Term
T helper cells recognize foreign antigen complexed with ~ |
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Definition
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Term
T helper 1 cells aid in ... T helper 2 cells aid in ... |
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Definition
regulation of cellular immunity B cell production of certain classes of antibodies |
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Term
T cytotoxic cells are cytotoxic against (2) |
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Definition
tumor cells cells infected with intracellular pathogens |
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Term
cytotoxic T cells usu express CD |
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Definition
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Term
T cytotoxic cells destroy infected cells in an antigen-specific manner that is dependent upon the expression of ~ molecules on ~ cells |
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Definition
MHC class I antigen-presenting |
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Term
T suppressor cells suppress |
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Definition
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Term
T suppressor cells express _ molecules |
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Definition
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Term
NKT cells are actually _ cells that share properties of both |
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Definition
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Term
NKT cells recognize an antigen presenting molecule _ that binds to ... |
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Definition
CD1d self- and foreign lipids and glycolipids |
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Term
NK cells nonspecifically kill (2) |
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Definition
tumor cells virus-infected cells |
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Term
NK cells are able to kill _ in the absence of _ _ receptors |
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Definition
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Term
_ cells are especially effective against viral infected cells |
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Definition
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Term
NK cells secrete _ _ which is an effective immunoregulator |
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Definition
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Term
NK cells can kill via ~ using their _ receptors |
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Definition
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Term
antigen presenting cells are found primarily in (4) |
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Definition
skin, lymph nodes, spleen, thymus |
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Term
two cells in brain that can do phagocytosis |
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Definition
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Term
10 antigen presenting cells |
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Definition
monocytes macrophages langerhans cells dendritic cells B cells T cells astrocytes thyroid follicular cells endothelium fibroblasts |
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Term
antigen-driven proliferation and differentiation take place in _ lymphoid organs |
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Definition
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Term
B and T cells differentiate from stem cells in _ lymphoid organs |
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Definition
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Term
T lymphocytes learn to recognize self antigens as self where? |
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Definition
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Term
only _ % of maturing T lymphocytes survive and leave the thymus |
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Definition
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Term
B cells differentiate in the fetal _ |
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Definition
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Term
B cells differentiate in the adult _ |
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Definition
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Term
major secondary lymphoid organs; (2) others include (7) |
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Definition
spleen lymph nodes
tonsils appendix Peyer's patches MALT BALT GALT bone marrow |
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Term
lymph nodes have a _ cell cortex and a _ cell paracortex as well as a central medulla |
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Definition
B cell cortex T cell paracortex |
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Term
lymphoid tissue of spleen is in the _ pulp |
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Definition
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Term
white pulp of spleen is arranged around a _ _ as a _ |
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Definition
central arteriole periarteriolar lymphoid sheath PALS |
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Term
within the PALS (specifically, within its _ _) are (2) which present antigen |
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Definition
dendritic reticular cells phagocytic macrophages |
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Term
monocytes are circulating _ precursor |
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Definition
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Term
_ cells are responsible for initiation of adaptive responses |
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Definition
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Term
rank from most to least numerous in blood -- monocyte, basophil, neutrophil, eosinophil |
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Definition
neutrophil monocyte eosinophil basophil |
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Term
...are responsible for adaptive cell-mediated immunity |
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Definition
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Term
B cells process and present _ antigens |
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Definition
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