Term
| The 4 cardinal signs of inflammation |
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Definition
1) calor
2) Rubor
3) tumor
4) dolor |
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Term
| 4 responses of the inflammation phase |
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Definition
1) vasoconstriction
2) Vasodilation
3) Clot Formation
4) Phagocytosis |
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Term
| Increased Redness and temperature |
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Definition
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Term
| What is caused by increased permeability and vasodilation of blood vessels and infiltration of fluid to the interstitial space |
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Definition
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Term
| Results from pressure of swelling and irritation by chemicals released from damaged cells |
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Definition
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Term
| Mediators that act to control inflammatory phase |
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Definition
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Term
| What cells predominate after an injury |
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Definition
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Term
| Neutrophils are replaced with 2 days after an injury |
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Definition
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Term
| Last for 5-10 min in an attempt to minimize blood loss |
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Definition
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Term
| last for up to 1 hour and is initiated by histamine |
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Definition
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Term
| Factor that activates coagulation and causes vaosconstriction |
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Definition
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Term
1) Breaks down fibrin
2) augments vascular permeability
3) activates hageman factor |
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Definition
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Term
| Released in response to any damage to the cell membrane |
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Definition
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Term
| Inhibits prostogladin synthesis |
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Definition
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Term
| Prostogladin that Increases vascular permeability by antagonizing vasoconstriction |
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Definition
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Term
Prostogladin that
1) Attracts leukocytes
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Definition
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Term
| Responsible for febrile state |
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Definition
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Term
| Process by which neutrophils break away from central cellular column of blood |
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Definition
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Term
| 3 phases in the attraction of blood to the vessel walls |
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Definition
1)Extravastion
2) Pavementing
3) Margination |
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Term
| Squezzing of Neutrophils through the cell walls |
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Definition
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Term
| process of leukocyte migration from the blood vessel to the perivascualar tissue |
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Definition
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Term
| accumulation of fluid in the extravascular sapce |
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Definition
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Term
| edema is resulting from 4 things |
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Definition
1) increased capiallry hydostatic pressure
2) incresed interstitial osmotic pressure
3) increased venule permeability
4) overwhemed lympatic system |
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Term
| fluid made up of few cells. little protien, dissolved elctrolytes and water |
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Definition
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Term
| cloudy viscous fluid with plasm protiens, high content of lipids. Eg blisters |
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Definition
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Term
| what is reduced in the vessels from the loss of protien rich fluid |
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Definition
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Term
| fluid with incresed leukocytes |
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Definition
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Term
| supportive exudate occuring in a solid tissue |
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Definition
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Term
1) endothelial cell contration
2) direct endothelia injury
3) leukocyte dependent endothelial injury
4) regenerting capilaries |
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Definition
| mechanisms for leakage and distribution |
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Term
| response that controls blood loss when vessels are damaged |
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Definition
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Term
| from a temporary plug which confines teh inflammtion phase to 1 area |
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Definition
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Term
| accumulation of blood in the tissue or organ |
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Definition
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Term
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Definition
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Term
| leukocyte that rids the area of debris by phagocytosis |
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Definition
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Term
| leukocyte that releases histamine |
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Definition
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Term
| considerd the most important cell in teh inflammatroy phase and is essential for wound healing |
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Definition
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Term
| most importatn plama protien system of inflammation |
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Definition
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Term
| system that increases vascular permeability, stimulates phagocytosis and acts as a chemostatic stimuli for leukocytes |
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Definition
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Term
| phase that is for strenght to the injury site and cover the wound |
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Definition
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Term
| four processes of the proliferation phase |
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Definition
1)epithelialization
2) collagen production
3) wound contraction
4) neovascularization |
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Term
| reestablishemnt of the epidermis, provide protective barrier to prevent fluid and electrolyte loss |
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Definition
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Term
| tissue containing newly formed capilaries, fibroblasts and myofibroblasts |
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Definition
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Term
| draws water into the area, increases the amount of intracellular matrix, and facilitates cellular migration |
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Definition
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Term
The relationship of _____ and ____ dictate the scar architecture |
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Definition
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Term
| what day is the collagen at the max |
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Definition
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Term
| how strong is a wound 6 wks after an injury |
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Definition
| 805 of its fulle strength |
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Term
| primary cells responsible for wound contraction |
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Definition
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Term
| If wound contraction is too fast then it can result in the formation of ? |
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Definition
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Term
| Neovascularization, the development of a new blood supply to the injured area |
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Definition
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Term
| primary collagen found in bone, skin, & tendon |
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Definition
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Term
| predominant collagen found in cartilage |
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Definition
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Term
| this collagen GI tract, uterus, & blood vessels, the 1st type of collagen to be deposited during the healing process |
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Definition
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Term
| rate of collagen production is much greater lysis |
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Definition
| keloid or hypertrophic scar |
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Term
| although raised, remain within the margins within the original wound |
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Definition
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Term
| scar attempts to mimic the characteristic of the tissue it is healing |
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Definition
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Term
| internal & external stresses placed on the injured area during the maturation phase determine the final tissue structure |
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Definition
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Term
| simultaneous progression of active inflammation, tissue destruction, and healing |
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Definition
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Term
| primary cells present during chronic inflammation |
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Definition
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Term
| a limited ability to heal because it lacks lymphatics, blood vessels, and nerves |
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Definition
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Term
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Definition
| synovial sheath is injured |
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Term
| Bone goes through 4 histologically distinct stages in the healing process |
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Definition
•1. inflammation, 2. soft callus, 3. hard callus, 4. bone remodeling |
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Term
| stage when cells that possess osteogenic capabilities are activated |
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Definition
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Term
| stabilize the fracture site, decrease pain, lessen the likelihood of a fat embolism |
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Definition
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Term
| begins when pain & swelling subside & lasts until the bony fragments are united |
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Definition
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Term
| begins when a sticky, hard callus covers the ends of the fracture & ends when new bone unites with the fragments |
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Definition
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